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We have 292 therapeutic PhD Projects, Programmes & Scholarships

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therapeutic PhD Projects, Programmes & Scholarships

We have 292 therapeutic PhD Projects, Programmes & Scholarships

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Investigation of the role of STAMBP as a therapeutic target in oesophageal cancer

  Research Group: The Patrick G Johnston Centre for Cancer Research
Publicly available data from CRISPR knock out screens in hundreds of cell lines suggests a strong dependency on STAMBP in oesophageal cancer. Read more

Therapeutic potential of neurosteroids in the treatment of anxiety and social avoidance

Neurosteroids are naturally occurring steroid compounds produced by the brain in response to stressful events, and they may serve a protective function by reducing the adverse consequences of stress, such as maladaptive increases in avoidance behaviour and anxiety that interfere with daily life. Read more

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

One in two people will develop cancer in their lifetime and it is a leading cause of death.  While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. . Read more

Developing novel targeted therapeutic approaches through induced-proximity of proteins

Protein post-translational code is at the heart of protein function and signal transduction in cells. Enzymes catalyse the addition or removal of post-translational modifications (PTM), such as phosphorylation, methylation, acetylation, and ubiquitylation, on proteins. Read more

A Hybrid Plasma Accelerator for Therapeutic Electron Beams

Would you like to join us at the University of Manchester to change the future of particle accelerators?. Using the available studentship, you will explore combining mature electron production technology with new plasma-based acceleration. Read more

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

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