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We have 34 infection model PhD Projects, Programmes & Scholarships

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infection model PhD Projects, Programmes & Scholarships

We have 34 infection model PhD Projects, Programmes & Scholarships

CRISPR/Cas9 probing of virulence factors in dermatophytes

One of the most widespread fungal infections affecting 20-25% of the global population is dermatophytosis. This is caused by fungi that infect the skin, nails, and hair, leading to common conditions such as athlete’s foot or ringworm. Read more

Competition and cooperation relationships within human microbial communities.

Typical studies of the human microbiome identify dysbiosis by sampling from healthy individuals, comparing them to individuals with a particular disease state, and reporting changes in the presence and/or abundance of bacterial species. Read more

The impact of nutritional scavenging on host-pathogen interactions, antifungal efficacy and emergence of antifungal resistance

Infections caused by Aspergillus fumigatus (Af) cause more deaths globally than any other fungal disease. Over 20 million are affected annually with four million having life threatening invasive and chronic infections with high morbidity and mortality up to 90%. Read more

The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more

Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

Viruses, these tiny but potent life forms, are all around us, infecting various organisms and directly affecting human health. Although in most cases, viral infection is not life threatening, in the minority of cases it leads to long-term disorders including cancer. Read more

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more

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