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We have 52 antibiotic PhD Projects, Programmes & Scholarships

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antibiotic PhD Projects, Programmes & Scholarships

We have 52 antibiotic PhD Projects, Programmes & Scholarships

Optimizing phage-antibiotic-synergies to kill bacterial pathogens

Phage therapy, the use of viruses that only infect bacterial cells and kill them, is a promising potential solution to the antimicrobial resistance crisis that is threatening modern medicine1. Read more

Microbiology of Hip Arthroplasty Cements

  Research Group: Centre for Skin Sciences
Replacement hip and knee arthroplasties are common surgeries, with 31,000 hip and 90,000 knee replacements performed in England in 2020-21. Read more

Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

  Research Group: Astbury Centre for Structural Molecular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more

Data science and child health inequalities

We are excited to share this application for a 4-year PhD studentship based in the Division of Child Health, University of Liverpool, in conjunction with Alder Hey Children’s Hospital, Liverpool, and Imperial College London. Read more

Vitamin B12 conjugates for the targeted uptake of antibiotics

About the Project. Join us in the innovative project “Developing vitamin B. 12. conjugates for the targeted uptake of antibiotics in resistant Gram-negative pathogens”. Read more

Novel strategy for treatment of chronic wounds via multi-functional liposomal nanocarriers

  Research Group: Medicines Development and Pharmaceutical Sciences
A confounding issue of non-healing skin wounds is the presence of pathogenic bacteria, that protect themselves from conventional antibiotic treatments by encasing themselves within protective shields (biofilms). Read more

Modification of antibiotics to improve efficacy / safety

With increasing concern over antibiotic resistance, antibacterial agents such as chloramphenicol and colistin, which have frequently been passed over in the past because of concerns over toxicity, are now becoming more important to tackle resistant bacterial strains. . Read more

Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more

Self-funded PhD- Understanding the molecular mechanism of a bacterial genome defence system and its synergy with CRISPR-Cas

Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well-studied of which are the Restriction-Modification and the CRISPR-Cas enzymes. Read more

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