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arthritis PhD Projects, Programmes & Scholarships

We have 27 arthritis PhD Projects, Programmes & Scholarships

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Inflammatory Arthritis in Childhood: Impact, Outcomes and Safety of Treatment

The University of Manchester Faculty of Biology, Medicine and Health
Juvenile Idiopathic Arthritis is the most common inflammatory arthritis of childhood. Although less common than arthritis in adults, a diagnosis of arthritis in a child can have lasting impacts on that child and their families through their entire lifespan. Read more
 Supervisors: Prof K Hyrich, Dr L Kearsley-Fleet
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identifying critical pathways regulating autoimmunity in immuno-oncology and arthritis patients. Short title: IPADS (Immune PAthways for Drug Side-effects)

The University of Manchester Faculty of Biology, Medicine and Health
Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies (inc. Read more
 Supervisors: Dr S Viatte, Prof A Barton, Mr P Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Early life factors in the development of Juvenile idiopathic arthritis

The University of Manchester Faculty of Biology, Medicine and Health
Juvenile idiopathic arthritis (JIA) is an autoimmune inflammatory arthritis with disease onset before the age of 16. Children and young people with this condition develop painful swollen joints and untreated it can lead to long term disability. It may also be associated with comorbid conditions such as uveitis. Read more
 Supervisors: Dr J Humphreys, Dr J Bowes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identification and characterization of disease-specific subsets of antigen-presenting cells (APC) in inflammatory arthritis

The University of Manchester Faculty of Biology, Medicine and Health
Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies. Read more
 Supervisors: Dr S Viatte, Prof A Barton, Mr P Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Adverse Events to Methotrexate in Inflammatory Arthritis: Does Age Matter?

The University of Manchester Faculty of Biology, Medicine and Health
A consistent top-5 research priority for both children and adults with inflammatory arthritis is the tailoring of treatments to prevent or lessen adverse events. Read more
 Supervisors: Dr S Shoop-Worrall, Prof K Hyrich, Dr S Verstappen
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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NIHR Leeds BRC: Unravelling the pre-clinical immunology of the IL-23/1L-17 axis in axial inflammation in psoriatic arthritis towards optimal disease prevention

University of Leeds Faculty of Medicine and Health
Psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are key disorders within the seronegative spondylarthropathy (SpA) that was first described in… Read more
 Supervisors: Prof D McGonagle, Dr H Marzo-Ortego, Dr T Macleod
 26 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Determining the biological basis of observed clinical outcomes in juvenile idiopathic arthritis using genetics and multiomics

The University of Manchester Faculty of Biology, Medicine and Health
Juvenile idiopathic arthritis (JIA) is a chronic inflammatory arthritis affecting children and young people with an age of disease onset less than 16 years of age. Read more
 Supervisors: Dr J Bowes, Dr J Humphreys
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences
Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more
 Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Pain increases disability; disability increases pain: Understanding the vicious cycle.

University of Nottingham School of Medicine
Arthritis affects 10 million people in the UK, and is on the rise. Many do not respond adequately to treatment. Pain is the main symptom, a leading cause of disability and worsens the risk of developing other health issues. Read more
 Supervisors: Dr SS Smith, Dr M Piasecki, Assoc Prof FM Moffatt
 30 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Clinical assessment and prediction of outcome post shoulder joint replacement using a smart device

University of York School of Physics, Engineering and Technology
More than 8000 shoulder replacements are performed annually in the UK alone, with numbers continuing to grow. Read more
 Supervisor: Dr P Ellison
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Improving access to work for people with Rheumatic and Musculoskeletal Diseases

University of Salford School of Health and Society
Over recent years, the Centre for Human Movement and Rehabilitation (CHMR) has received extensive investment allowing us to develop world-class research facilities for PhD study. Read more
 Supervisor: Dr Y Prior
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The Survivin Interactome in Health and Disease

University of Nottingham School of Life Sciences
Survivin is a small protein that is essential for life but that also contributes to disease, most notably cancer, in which its abnormal overexpression is linked to therapeutic resistance and metastasis. Read more
 Supervisor: Dr S Wheatley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The University of Manchester Faculty of Biology, Medicine and Health
The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more
 Supervisors: Dr MM Mennon, Prof MH Buch
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Biomechanics of internal fixation methods for ankle fusion

University of Sheffield Department of Mechanical Engineering
Ankle fusion is a common treatment for advanced ankle arthritis to relieve pain and improve functional outcomes. However, there is a reported non-union rate of 5-37%, requiring further surgery or an ankle replacement. Read more
 Supervisors: Dr V S Cheong, Prof C Brocket
 18 June 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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NIHR Leeds BRC: Targeting systemic inflammation to treat joint pain

University of Leeds Faculty of Medicine and Health
Osteoarthritis (OA) is the commonest arthritis and affects >530 million people globally; prevalent cases increased 113% since 1990. Read more
 Supervisors: Prof P Conaghan, Dr S Kingsbury
 26 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

University of Liverpool Institute of Life Course and Medical Sciences
Immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) affect millions of people worldwide and cause debilitating and disabling musculoskeletal disease. Read more
 Supervisors: Dr HL Wright, Prof MJ Peffers
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of neutrophil-mediated tissue damage in a model of lupus nephritis

University of Liverpool Institute of Life Course and Medical Sciences
Systemic lupus erythematosus (SLE) is a rare autoimmune disease that affects around 5 million people worldwide. It disproportionately affects women and is incurable. Read more
 Supervisors: Dr HL Wright, Dr D Wilkinson, Dr D Turner
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Translating biomarkers towards clinical trial application in osteoarthritis

Imperial College London Department of Immunology & Inflammation
Stipend. Standard Research Council London Rate + Tuition Fees (Home rate) for 3 years. A consumables budget is also provided. Applications are invited for a 3-year PhD studentship based in the Centre for Inflammatory Disease, Department of Immunology & Inflammation at Imperial College London. Read more
 Supervisor: Dr F Watt
 5 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Interdisciplinary investigation of a large effect of sulfasalazine on HbA1c

University of Dundee School of Medicine
The anti-inflammatory drug sulfasalazine, which is used in rheumatoid arthritis and inflammatory bowel disease, was reported earlier to suppress HbA1c in a small cohort of patients [1]. Read more
 Supervisors: Prof G Rena, Prof E Pearson
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more
 Supervisors: Dr M Hussain, Dr M Katsikogianni, Dr N Javid
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Helminth products as macrophage “trainers”: a novel tool to induce anti-inflammatory trained immunity

Kingston University Faculty of Health, Science, Social Care and Education
The innate immune system can display characteristics of immunological memory. This phenomenon, termed “trained immunity”, refers to the long-term functional reprogramming of innate immune cells after the encounter with infectious or non-infectious agents that influences their capacity to respond to a secondary stimulus. Read more
 Supervisor: Dr N Garrido Mesa
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Microneedle delivery systems for next-generation antibody therapeutics

Queen’s University Belfast School of Pharmacy
Microneedle arrays are minimally-invasive devices that painlessly, and without drawing blood, penetrate the skin’s stratum corneum barrier. Read more
 Supervisor: Prof R Donnelly
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating mechanical mechanisms underlying osteoarthritis

Cardiff University Cardiff School of Biosciences
Project Description. Osteoarthritis is the major global cause of pain and disability affecting nearly 30million people in the US and 10 million in the UK. Read more
 Supervisors: Dr D Mason, Dr SJG Gilbert
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular Mechanisms of Resolution of Inflammation

University of Birmingham Institute of Inflammation and Ageing
We are seeking talented, motivated students to join the research group led by Professor Andy Clark (https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/clark-andy.aspx), a member of the University of Birmingham’s Rheumatology Research Group (https://www.birmingham.ac.uk/research/inflammation-ageing/research/rheumatology-research-group/index.aspx). Read more
 Supervisor: Prof A Clark
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the genetic basis of immunological overlap between inflammatory diseases

The University of Manchester Faculty of Biology, Medicine and Health
Genetic studies have identified numerous variants within the human genome associated with susceptibility to common complex inflammatory diseases, such as rheumatoid arthritis (RA) and ulcerative colitis (UC). Read more
 Supervisors: Mr P Martin, Prof S Eyre, Prof A Morris
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Circadian mechanisms in psoriasis: therapeutic opportunities

The University of Manchester Faculty of Biology, Medicine and Health
Hallmark features of psoriasis symptoms vary through time, suggesting an important role for circadian circuits in driving disease expression, and offering the potential of chronotherapy. Read more
 Supervisors: Dr H Young, Dr I Iqbal, Prof D Ray
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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3 Year Funded Kennedy Trust IMPACT Inflammation MB-PhD

The University of Manchester Faculty of Biology, Medicine and Health
Combine the vocational training of a medical degree with the research expertise of a PhD. The Kennedy Trust IMPACT Inflammation MB-PhD is a funded three-year programme for undergraduate medical students who wish to train as clinician scientists. Read more
 Funded PhD Programme (Students Worldwide)  Clinical PhD Programme
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