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cell culture PhD Projects, Programmes & Scholarships

We have 255 cell culture PhD Projects, Programmes & Scholarships

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Diagnostics for FMF patients and carrier survival in pandemics

The University of Manchester Faculty of Biology, Medicine and Health
Background. Familial Mediterranean Fever (FMF) is a rare inherited genetic disease where patients acquire a mutation on the pyrin gene leading to excessive inflammasome activation and excessive inflammation. Read more
 Supervisors: Dr P Arkwright, Dr G Lopez-Castejon, Dr J Cavet
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of myocardial ischemic adaptation in the presence of comorbidity factors on in vitro cell culture models

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy
Metabolic derangements, such as obesity or diabetes, are major risk factors of cardiovascular diseases. Read more
 Supervisor: Dr A Görbe
 Year round applications  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Characterisation of how pro-peptide regions of collagen control extracellular matrix homeostasis, in health and musculoskeletal diseases

The University of Manchester Faculty of Biology, Medicine and Health
Collagen-I (‘collagen’ from hereon) is the most abundant protein in the human body (circa 25% of total protein mass), providing structure to organs with very different functions (e.g. Read more
 Supervisors: Dr JC Chang, Dr TZ Zacharchenko, Prof C Baldock
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Study of early pathological changes in calcified cartilage in osteoarthritis and alkaptonuria

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
We are seeking a motivated individual to work on this exciting project investigating the role that the calcified cartilage has in rare and common joint osteoarthritis, using novel approaches such as gene silencing and establishment of a 3D chondrocyte cell culture model. Read more
 Supervisor: Dr JH Hughes
 10 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Investigating immune contributions to frontotemporal dementia and motor neuron disease

The University of Manchester Faculty of Biology, Medicine and Health
Frontotemporal dementia (FTD) is the 2nd most common form of dementia affecting younger people, with a typical age of onset in the mid-late 50s. Read more
 Supervisors: Dr SR Ryan, Prof D Brough
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Possible role of mutant vimentin in cancer progression and metastasis

Queen Mary University of London Institute of Dentistry
Background. This project will investigate the role of the cytoskeletal protein vimentin in cancer progression and metastasis using cell and molecular biology approaches. Read more
 Supervisors: Prof A Waseem, Dr F Flores-Borja, Dr H Tummala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

University of Bristol Bristol Medical School
Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 T-cell responses. Read more
 Supervisor: Dr P Maghsoudlou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genomic actions of RAR and VDR ligands

Medical University of Vienna Institute for Pathophysiologie and Allergy
The Doctoral Candidate (DC) will determine whether the combination of RARγ antagonist and VDR agonist is suitable as a differentiation therapy against acute myeloid leukaemia (AML). Read more
 Supervisor: Prof E Marcinkowska
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Sensitizing AML cells to RAR and VDR ligands (vitamin A and D derivatives) to prevent leukaemia relapse

Medical University of Vienna Institute for Pathophysiologie and Allergy
The doctoral candidate (DC) will perform basic research on leukaemia cell biology in vitro and in vivo at the Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel. Read more
 Supervisor: Dr MD Danilenko
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

University of Portsmouth School of Pharmacy and Biomedical Sciences
Applications are invited for a self-funded, 3 year full-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. Read more
 Supervisors: Dr R Hadianamrei, Dr S Hafizi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding the link between fibrosis, inflammation, and breast cancer initiation

University of Leicester Molecular and Cell Biology
Understanding the fundamental molecular events that result in tumour initiation is critical to the prevention and treatment of human cancers. Read more
 Supervisor: Dr C Switzer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Importance of RARγ for malignant potential of AML blasts

Medical University of Vienna Institute for Pathophysiologie and Allergy
The Doctoral Candidate (DC) will determine the roles of retinoic acid receptors (RAR) α and γ in the development of acute myeloid leukaemia (AML). Read more
 Supervisor: Prof E Marcinkowska
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Engineering extracellular vesicles/exosomes for the treatment of ocular disease

Cardiff University Cardiff School of Optometry & Vision Sciences
Extracellular vesicles, also referred to as exosomes, are membrane‐bound particles containing huge numbers of proteins as well as genetic material in the form of RNA (mRNA and miRNA). Read more
 Supervisor: Dr B Mead
 5 August 2024  PhD Research Project  Self-Funded PhD Students Only
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MSc By Research: Assessing health benefits of gut microbiota using host-microbe interaction models of the human gut

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Dr S Gratz, Prof K Scott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating mechanisms of extra-cellular matrix remodelling and fibrosis in the gastrointestinal tract

University of Dundee School of Medicine
Inflammatory bowel diseases, such as Crohn's disease, are increasing in prevalence globally. These are caused by chronic inflammation in the gut, there is no cure and medications are not effective for all. Read more
 Supervisor: Dr M Mclean
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Elucidation of a new pathological mechanism for brittle bone disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
The incidence of the brittle bone disease osteogenesis imperfecta (OI) is estimated to be around 1 in 10,000 individuals. The phenotypic spectrum of OI ranges from mild to perinatal lethal and includes extra-skeletal connective tissue manifestations. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of vitamin D3 in treating skin cancer and preventing drug resistance

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
During the last decade numerous studies have alluded to vitamin D. 3. playing a role in the prevention of cancer. Recent clinical trials looking at the potential role of vitamin D. Read more
 Supervisors: Dr M Sutherland, Dr H Sheldrake, Dr S Kauser
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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4-year PhD Studentship: A novel, bacterial quorum sensor-infused nanocarrier drug delivery system to tackle antimicrobial resistant fungi

University of Bristol Bristol Dental School
Healthcare associated infections (HAI) remain an unresolved clinical issue that significantly impacts patients’ lives and global economies. Read more
 Supervisors: Dr N Bandara, Dr A Nobbs
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Preventing Ovarian Cancer, Colorectal Cancer, and Related Metastases

Medical University of Vienna Institute for Pathophysiologie and Allergy
The doctoral candidate (DC) will perform basic molecular biology research on in vitro and in vivo cancer models at the Medical University of Vienna, Austria. Read more
 Supervisors: Dr MSch Schepelmann, Prof E K Kallay
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks

Nottingham Trent University School of Science & Technology
The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children. Read more
 Supervisor: Dr A Antonysunil
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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What is the interrelationship between cell mitosis and cell polarity during apical-basal polarisation of epithelial organs?

The University of Manchester Faculty of Biology, Medicine and Health
My group strives to uncover how mechanics and biochemical signalling work together to shape epithelial organs during development. Read more
 Supervisors: Dr C.B Buckley, Dr S Woolner
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology
What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more
 Supervisors: Dr JF Fox, Dr JH Hodgkinson
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Optogenetic sculpting of next-generation organoids for disease modelling of congenital malformations including spina bifida

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
The ability to generate human induced pluripotent stem cells (iPSC) from adult cell types has revolutionised regenerative medicine research. Read more
 Supervisors: Dr G Galea, Prof J Sowden
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Treatment of Breast Cancer and Preventing Relapse

Medical University of Vienna Institute for Pathophysiologie and Allergy
The doctoral candidate (DC) The DC will perform biological basic research on cancer in vitro and in vivo at the CIMUS-University of Santiago de Compostela (Spain). Read more
 Supervisor: Prof RPF Pérez-Fernández
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Molecular Mechanisms of Receptor and Ion Channel Regulation in Pain and Inflammation

University of Reading School of Pharmacy
Are you ready to delve into the captivating world of molecular signaling and unravel the mysteries of the cardiovascular and nervous systems? We are thrilled to offer an exhilarating PhD opportunity at the forefront of scientific exploration. Read more
 Supervisors: Dr G Cottrell, Prof D Widera, Dr S Amadesi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding the role of spliceosome gene mutations in disease

The University of Manchester Faculty of Biology, Medicine and Health
The DNA of a cell is copied into a pre-messenger RNA (pre-mRNA) that the cell uses as a template for protein production. Some of the information contained in DNA is not required for making proteins, therefore, unwanted information must be removed before a protein is made. Read more
 Supervisors: Prof R O'Keefe, Prof B Newman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Advancing our understanding of mycoplasma and ureaplasma infections among humans and animals

Cardiff Metropolitan University Cardiff School of Sport and Health Sciences
The Mycoplasma and Ureaplasma Group based at Cardiff Metropolitan University is seeking motivated and enthusiastic students to undertake research projects on various aspects of Mycoplasma and Ureaplasma spp infection. Read more
 Supervisors: Dr M Beeton, Dr R Aicheler, Dr J Blaxland, Dr S Maddocks
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Nuclear and transcriptional dysregulations during cellular senescence

University of Leicester Molecular and Cell Biology
Cellular senescence, which is characterised by a proliferation arrest, is a driver of ageing (1). Several stresses can induce cellular senescence, including persistent DNA damage, telomere dysfunction, and oncogene activation. Read more
 Supervisors: Dr MT Tellier, Dr Y Markaki
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Evaluating the impact of genotoxic aldehyde stress in premature ageing

University of Leicester Department of Chemistry
Aldehydes are highly reactive chemicals that are common pollutants and human metabolites. However, the vast majority of aldehydes’ biological functions are unknown. Read more
 Supervisors: Dr R Hopkinson, Dr K Tanaka
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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NUAcT PhD Studentship: Drug discovery in Motor Neuron Disease

Newcastle University Translational and Clinical Research Institute
Award summary. An annual stipend equivalent to UKRI doctoral stipend (23/24 rate at £18,622). Full fees at the UK home rate. International candidates will need to pay the difference between home and international fees. Read more
 Supervisor: Dr HED Devine
 26 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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