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We have 95 disorder PhD Projects, Programmes & Scholarships

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disorder PhD Projects, Programmes & Scholarships

We have 95 disorder PhD Projects, Programmes & Scholarships

Understanding the factors that influence psychosocial functioning in older people with bipolar disorder

Bipolar disorder is classified as a lifelong, recurrent condition, associated with functional decline and a reduction in quality of life (Michalak et al., 2005; Bonnín et al., 2012). Older adults are estimated to represent approximately 25% of people diagnosed with bipolar disorder (Ljubic et al., 2021). Read more

Funded PhD - Determining the genetic and circadian basis of bipolar disorder

This project will be part of the University of Bristol - University of Kent Cotutelle Programme. It will be jointly supervised by Prof James Hodge (http://www.bristol.ac.uk/phys-pharm-neuro/people-new/hodge/) and Dr Alice French at the University of Bristol, and by Prof Gurprit Lall at University of Kent. Read more

MScR - Determining the genetic and circadian basis of bipolar disorder using Drosophila

Circadian rhythms and sleep are evolutionarily conserved from fruit flies (Drosophila) and are fundamental as well as vital to biology and health (Jagannath et al., 2017; Menet and Rosbash, 2011). Read more

Understanding how mutations in the kinase TLK2 cause a neurodevelopmental disorder

Tousled-like kinase 2 (TLK2) was recently identified as a novel genetic locus for a neurodevelopmental disorder. Patients predominantly possess de novo mutations in TLK2, leading to a reduction in its expression or kinase activity. Read more

Studying disordered materials by 3D electron diffraction

Structural disorder in materials can be an important method of understanding their properties for a wide range of applications. However detecting and modelling disorder at the nanoscale can be a difficult undertaking. Read more

Investigating monogenic disorders of the protein synthesis machinery

Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more

Novel disease genes in brain development and decline

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Understanding the neural basis of ADHD

Attention Deficit Hyperactivity Disorder (ADHD) is the most prevalent neurodevelopmental disorder, however the neural changes that underlie the disorder are poorly understood. Read more

Advancing translational cell therapy for Hirschsprung disease

Clinical disorders characterised by neuronal loss or dysfunction in the gastrointestinal tract remain some of the most challenging to manage, with considerable morbidity and mortality and very limited treatments. Read more

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