drug discovery PhD Projects, Programmes & Scholarships

Data-driven realisation of molecular editing for drug discovery

University of Leeds Faculty of Engineering and Physical Sciences

Drug discovery pipelines are driven by iterative cycles in which molecules are designed, synthesised, purified and tested. A remarkably limited toolkit… Read more

Supervisors: Prof A Nelson, Prof S Marsden

6 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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MSc by Research: Clustering the protein universe across the Tree of Life to enhance drug discovery

University of Dundee School of Life Sciences

Drug discovery is the systematic process of identifying and optimizing molecular compounds to develop targeted medications for medical conditions. Read more

Supervisors: Dr H Drost, Prof G J Barton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of a novel automatised platform for drug discovery in relevant human tissue models

University College London UCL Great Ormond Street Institute of Child Health

A 4-year funded PhD studentship is available in the UCL GOS Institute of Child Health “Developmental Biology and Cancer” department. Read more

Supervisors: Dr D Stoyanov, Prof P De Coppi, Dr GGG Giobbe

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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NUAcT PhD Studentship: Drug discovery in Motor Neuron Disease

Newcastle University Translational and Clinical Research Institute

Award summary. An annual stipend equivalent to UKRI doctoral stipend (23/24 rate at £18,622). Full fees at the UK home rate. International candidates will need to pay the difference between home and international fees. Read more

Supervisor: Dr HED Devine

26 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

The University of Manchester Faculty of Biology, Medicine and Health

Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more

Supervisors: Dr A Politis, Dr CP Pliotas

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Phosphine Oxides as Rising Stars in Drug Discovery

Imperial College London Institute of Chemical Biology

Phosphine oxides represent a noticeably underrepresented chemotype in drug discovery. Read more

Supervisor: Dr J Bull

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Maastricht University Cardiovascular Research Institute Maastricht (CARIM)

Applications can only be submitted via our website. The specific position for Doctoral Candidate 6 (DC6) in the consortium, which is part of Work Package 2 (WP2), aims. Read more

Supervisor: Dr G Nicolaes

30 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Combining CRISPR-screens and AI to Identify Novel Therapeutic Strategies to Target Cancer-Stroma Interactions

Queen Mary University of London Digital Environment Research Institute

A fully funded PhD Studentship is available to work with Dr Angus Cameron, Reader in Cell Signalling and Tumour Cell Biology, Barts Cancer Institute at Queen Mary University London, Dr Otto Morris, Senior Biological Data Scientist at Exscientia, and Professor Pedro Cutillas, Professor of Cell Signalling and Proteomics, QMUL, Barts Cancer Institute at Queen Mary University London. Read more

Supervisor: Dr A Cameron

6 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Small molecule cancer drug discovery targeting resistant disease.

Cardiff University Cardiff School of Pharmacy and Pharmaceutical Sciences

Despite continuous advances in targeted cancer therapy in recent years, there remains a major challenge to combat drug resistance and poor levels of efficacy in areas of unmet medical need, such as advanced colorectal and breast cancer. Read more

Supervisor: Prof A Westwell

17 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Supervisor: Dr Muhammad Wahajuddin

Year round applications PhD Research Project Self-Funded PhD Students Only

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AI-based Identification of New Drug Targets for Personalised Oncology

Queen Mary University of London Digital Environment Research Institute

A fully funded PhD Studentship is available to work with Professor Francesca Ciccarelli, Lead of the Centre for Cancer Genomics and Computational Biology, Bart's Cancer Institute at Queen Mary University of London. Read more

Supervisor: Prof F Ciccarelli

6 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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PhD in Pre-Clinical Drug Discovery

Lancaster University Biomedical and Life Sciences

Antibiotic resistance presents a significant global challenge, with profound consequences for public health, economic burdens, and human lives. Read more

Supervisors: Dr D Clancy, Dr M Munir, Prof D Middleton

31 July 2024 PhD Research Project Self-Funded PhD Students Only

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Photoredox molecular editing for enhanced drug discovery

The University of Manchester Department of Chemistry

Molecular editing platforms, the process by which single atoms can be inserted or deleted selectively in or around a molecule’s skeleton, are transformative to synthetic chemists across industry and academia for the streamlined development of new drugs. Read more

Supervisor: Dr A Trowbridge

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

University of Leeds Faculty of Biological Sciences

Research Group: Astbury Centre for Structural Molecular Biology

Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more

Supervisors: Prof A O'Neill, Dr M McPhillie, Prof C Fishwick

Year round applications PhD Research Project Self-Funded PhD Students Only

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Towards new antibacterial drugs to treat infections caused by multidrug-resistant bacteria: identification and characterization of novel natural product antibiotics

University of Leeds Faculty of Biological Sciences

Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to the average human lifespan. Read more

Supervisor: Prof A O'Neill

Year round applications PhD Research Project Self-Funded PhD Students Only

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Interrogation of the digital biopharmaceutics toolbox: Predictions of biorelevant solubility and dissolution profiles

University of Strathclyde Strathclyde Institute of Pharmacy & Biomedical Sciences

Digital tools play a crucial role in various aspects of pharmaceutical research, aiding in data analysis, modelling and simulation. Read more

Supervisor: Prof HB Batchelor

Year round applications PhD Research Project Self-Funded PhD Students Only

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Transcriptome biomarkers and mechanisms of chemoresistance

Queen Mary University of London Institute of Dentistry

Project Summary. This project aims to identify biomarkers linked to the most potent multimodal anticancer therapy with the least toxicity to counteract hemoresistance in head and neck squamous cell carcinoma (HNSCC). Read more

Supervisor: Dr M T Teh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Towards the development of a novel class of broad-spectrum anti-infective drugs

University of Strathclyde Department of Pure and Applied Chemistry

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more

Supervisor: Dr FS Scott

Year round applications PhD Research Project Self-Funded PhD Students Only

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Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Coronavirus now labelled as Covid-19 has become a global pandemic affecting around 200 countries. Currently neither any cure nor any vaccine for Covid-19 has been established. Read more

Supervisor: Dr T Nasim

Year round applications PhD Research Project Self-Funded PhD Students Only

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Transcriptome homeostasis in cellular ageing and cancer

Queen Mary University of London Institute of Dentistry

Project Summary. We have previously established the oncogenic mechanisms of the transcription factor FOXM1 in perturbation of genome stability (1, 2), epigenome (3, 4) and adult progenitor epithelial stem cell proliferation (5). Read more

Supervisor: Dr M T Teh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Testing the translational power of zebrafish for studying human heart failure. Ref: 5101

University of Exeter BBSRC South West Doctoral Training Partnership

Supervisors. Dr Matthew Winter, University of Exeter. Dr Yosuke Ono, University of Exeter. Location. Biosciences, Streatham Campus, Exeter. Read more

Supervisors: Dr M Winter, Dr YO Ono

22 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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An Investigation into the role of Altered Molecular Signalling in Drug Resistance Prostate Cancer

University of Sunderland Faculty of Health Sciences and Wellbeing

University of Sunderland, John Dawson Drug Discovery and Development Research Institute. 3-year Funded PhD studentship. Supervisors. Read more

Supervisors: Dr S Darby, Dr NC Carter

25 July 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and Development of Small Molecule Modulators of the Hippo Signalling Pathway for Enhanced Cancer Immunotherapy

Kingston University Faculty of Health, Science, Social Care and Education

Candidates are invited to join the Kadri Lab, where our research focuses on developing innovative chemical approaches for discovering novel therapeutics to address unmet global health needs. Read more

Supervisor: Dr H Kadri

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Predicting drug solubility in different solvents using molecular simulation and machine learning

University of Strathclyde Department of Chemical and Process Engineering

Predicting the solubility of complex drug-like molecules is crucial at several stages of the drug discovery and manufacture. In particular, solvent selection has been highlighted as a crucial step in process design and optimisation [1]. Read more

Supervisors: Dr M Jorge, Prof C Price

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

University of Liverpool Institute of Life Course and Medical Sciences

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

Supervisor: Dr VPV Pekovic-Vaughan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Harnessing Breast Cancer Therapy: Innovative Formulation Strategies for Repurposing Medicines to Overcome Resistance

Kingston University Faculty of Health, Science, Social Care and Education

Background. Research in the Kadri group focuses on developing innovative chemical approaches for the discovery of novel therapeutics to address unmet global health needs. Read more

Supervisor: Dr H Kadri

Year round applications PhD Research Project Self-Funded PhD Students Only

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The use of Drosophila melanogaster to identify novel therapeutic agents for Alzheimer’s disease

University of Nottingham School of Life Sciences

Since 2003, our understanding of the causes of Alzheimer’s disease (AD) have improved considerably, however, in that time only one new drug treatment has been approved. Read more

Supervisors: Dr M Georgiou, Dr Z Zhu

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular Glues as Novel Tools for Tackling Big Challenges in Human Health

University of Leicester Department of Chemistry

Background. The need for new medicines is greater than ever because of an ageing population and the complex clinical challenges brought about by drug resistance and/or side effects. Read more

Supervisors: Dr RD Doveston, Prof S Macip

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Treating Glioblastoma: Tricyclic antidepressants repositioned and administered as a cancer therapy by a novel nanoparticle delivery system in vitro

Kingston University Faculty of Health, Science, Social Care and Education

Cancer is a disease that is rapidly increasing. The initiation and progression of cancer is a central topic of countless research with discoveries of multiple pathways implicated in formation and advancement of this debilitating disease. Read more

Supervisor: Dr A Elbediwy

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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We have 99 drug discovery PhD Projects, Programmes & Scholarships

drug discovery PhD Projects, Programmes & Scholarships

We have 99 drug discovery PhD Projects, Programmes & Scholarships

Data-driven realisation of molecular editing for drug discovery

MSc by Research: Clustering the protein universe across the Tree of Life to enhance drug discovery

Development of a novel automatised platform for drug discovery in relevant human tissue models

NUAcT PhD Studentship: Drug discovery in Motor Neuron Disease

(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

Phosphine Oxides as Rising Stars in Drug Discovery

In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Combining CRISPR-screens and AI to Identify Novel Therapeutic Strategies to Target Cancer-Stroma Interactions

Small molecule cancer drug discovery targeting resistant disease.

Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

AI-based Identification of New Drug Targets for Personalised Oncology

PhD in Pre-Clinical Drug Discovery

Photoredox molecular editing for enhanced drug discovery

Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

Towards new antibacterial drugs to treat infections caused by multidrug-resistant bacteria: identification and characterization of novel natural product antibiotics

Interrogation of the digital biopharmaceutics toolbox: Predictions of biorelevant solubility and dissolution profiles

Transcriptome biomarkers and mechanisms of chemoresistance

Towards the development of a novel class of broad-spectrum anti-infective drugs

Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

Transcriptome homeostasis in cellular ageing and cancer

Testing the translational power of zebrafish for studying human heart failure. Ref: 5101

An Investigation into the role of Altered Molecular Signalling in Drug Resistance Prostate Cancer

Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

Discovery and Development of Small Molecule Modulators of the Hippo Signalling Pathway for Enhanced Cancer Immunotherapy

Predicting drug solubility in different solvents using molecular simulation and machine learning

Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

Harnessing Breast Cancer Therapy: Innovative Formulation Strategies for Repurposing Medicines to Overcome Resistance

The use of Drosophila melanogaster to identify novel therapeutic agents for Alzheimer’s disease

Molecular Glues as Novel Tools for Tackling Big Challenges in Human Health

Treating Glioblastoma: Tricyclic antidepressants repositioned and administered as a cancer therapy by a novel nanoparticle delivery system in vitro

We have 99 drug discovery PhD Projects, Programmes & Scholarships

drug discovery PhD Projects, Programmes & Scholarships

We have 99 drug discovery PhD Projects, Programmes & Scholarships

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