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We have 460 heart PhD Projects, Programmes & Scholarships

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heart PhD Projects, Programmes & Scholarships

We have 460 heart PhD Projects, Programmes & Scholarships

Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more

Biomechanical signalling in human heart disease

About the Project. The human heart undergoes more than 2 billion beats throughout an individual's lifetime, with its rhythm precisely regulated by signalling events that continuously adapt to the biomechanical stress exerted on the ventricular walls. Read more

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

  Research Group: Chemistry and Biosciences
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

The Role of Reactive Sulfur Species in the Ageing Heart

Second Supervisor. Prof Melanie Madhani, University of Birmingham. Background . Ageing is a natural and complex biological process that involves the gradual deterioration of cells, tissues, and organ systems over time, thus leading to an increased susceptibility to diseases and mortality. Read more

AI Powered Personalized Virtual Heart Modelling

Supervisory Team: Dr Lei Li, Prof. Age Chapman. Project description. In this unique PhD project, we aim to develop advanced AI models for creating cardiac digital twins, i.e., virtual heart models. Read more

Regulation of protein palmitoylation in the heart by persulphidation

Hydrogen sulphide (H2S) is known to have cardioprotective qualities. Persulphidation is a reversible post-translational modification (PTM) in which a persulphide group is formed by the reaction of H2S with the thiol groups of cysteine residues in proteins. Read more

Investigating the metabolic link between leukaemia and heart failure (RUSHWORTHS_U24BIGC)

Primary supervisor - Dr Stuart Rushworth. Secondary supervisor - Dr James Smith. Rushworth Lab. This 4-year PhD project funded by the Big C cancer charity represents an exciting opportunity to develop and conduct research at the forefront of cancer research. Read more

Ageing to Arrhythmias

Cardiac arrhythmias are a leading cause of sudden death and morbidity. This project aims to identify why they occur in the elderly and novel routes to therapies. Read more

Exploring cardio-renal-metabolic interactions in patients with heart failure

Recent years have highlighted the connections and shared pathophysiology between heart failure, renal impairment, diabetes and obesity, particularly with the evidence of benefit in all of these areas with SGLT2 inhibitors and GLP1-receptor agonists. Read more

Cardiac Harmony: Modelling Heart Beats with Stem Cells and Code

Despite significant advancements in cardiac research, heart disease remains a leading cause of mortality globally. Unexpected cardiac events can occur even in young, fit individuals engaged in routine activities. Read more

Towards developing novel actuation method of soft robotic devices towards medical applications

  Research Group: Healthcare Engineering
Beating-heart procedures represent a less invasive alternative to standard open-heart surgery with fewer perioperative complications, and shorter recovery time. Read more

NIHR Leeds BRC: Force sensing mechanisms of haemostasis in heart failure and diabetes

Since the original identification of the role of PIEZO1 in vascular integrity and endothelial cell biology by our group in Leeds in 2014, there have been many publications on the role of PIEZO1 in endothelial function and its role in processes such as atherosclerosis, hypertension, cell-cell junctions, vascular permeability and leukocyte diapedesis. Read more

Disease mechanisms in the heart

We are seeking talented, motivated students with a passion for research in inherited cardiac conditions (cardiomyopathies) and biomechanical stress signalling led by Dr Katja Gehmlich (https://www.birmingham.ac.uk/staff/profiles/cardiovascular-sciences/gehmlich-katja.aspx). Read more

Investigating the mechanisms for cardiac fibrosis development and reversal

Research interests/description of main research theme. Fibrosis is a hard to treat condition of major socioeconomic importance, with ~45% of all deaths in the developed world being attributed to some type of chronic fibro-proliferative disease and is exemplified by heart disease. Read more

Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

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