infection model PhD Projects, Programmes & Scholarships

CRISPR/Cas9 probing of virulence factors in dermatophytes

University of Bath Department of Life Sciences

One of the most widespread fungal infections affecting 20-25% of the global population is dermatophytosis. This is caused by fungi that infect the skin, nails, and hair, leading to common conditions such as athlete’s foot or ringworm. Read more

Supervisor: Dr A Bolhuis

Year round applications PhD Research Project Self-Funded PhD Students Only

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4-year PhD Studentship: A novel, bacterial quorum sensor-infused nanocarrier drug delivery system to tackle antimicrobial resistant fungi

University of Bristol Bristol Dental School

Healthcare associated infections (HAI) remain an unresolved clinical issue that significantly impacts patients’ lives and global economies. Read more

Supervisors: Dr N Bandara, Dr A Nobbs

Year round applications PhD Research Project Self-Funded PhD Students Only

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Competition and cooperation relationships within human microbial communities.

University of Nottingham School of Life Sciences

Typical studies of the human microbiome identify dysbiosis by sampling from healthy individuals, comparing them to individuals with a particular disease state, and reporting changes in the presence and/or abundance of bacterial species. Read more

Supervisors: Dr F Whelan, Dr K Hardie

Year round applications PhD Research Project Self-Funded PhD Students Only

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Mapping CD4+ T cell fate decisions and functional coordination within tissues during infection

The University of Manchester Faculty of Biology, Medicine and Health

CD4+ T cells are essential components of the immune system, orchestrating protection against infection. Read more

Supervisors: Dr K Couper, Prof DD Dyer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Host Pathogen Interaction: Investigating the function of Natural Killer Cells in Bacterial Infection

Cardiff Metropolitan University Cardiff School of Sport and Health Sciences

Natural Killer (NK) cells are immune cells that are critical for controlling intracellular pathogens, including viruses and intracellular bacteria (e.g. Read more

Supervisors: Dr R Aicheler, Dr M Beeton, Dr J Blaxland, Dr S Maddocks

Year round applications PhD Research Project Self-Funded PhD Students Only

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The impact of nutritional scavenging on host-pathogen interactions, antifungal efficacy and emergence of antifungal resistance

The University of Manchester Faculty of Biology, Medicine and Health

Infections caused by Aspergillus fumigatus (Af) cause more deaths globally than any other fungal disease. Over 20 million are affected annually with four million having life threatening invasive and chronic infections with high morbidity and mortality up to 90%. Read more

Supervisors: Dr N.V.R Van Rhijn, Dr M Bromley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Greenwich School of Pharmacy (Medway Campus)

Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more

Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves

Year round applications PhD Research Project Self-Funded PhD Students Only

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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Kent Medway School of Pharmacy

Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more

Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves

Year round applications PhD Research Project Self-Funded PhD Students Only

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The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

The University of Manchester Faculty of Biology, Medicine and Health

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more

Supervisors: Dr R Hager, Dr M Harte, Dr J Glazier

Year round applications PhD Research Project Self-Funded PhD Students Only

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Microbial Community Dynamics and Biocide Susceptibility Profiles in Chronic Wound Biofilms

Sheffield Hallam University Biomolecular Sciences Research Centre

The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more

Supervisors: Dr S Forbes, Dr KM Miller, Dr N Aberdein, Dr F Clegg

10 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

University of York York Biomedical Research Institute

Viruses, these tiny but potent life forms, are all around us, infecting various organisms and directly affecting human health. Although in most cases, viral infection is not life threatening, in the minority of cases it leads to long-term disorders including cancer. Read more

Supervisors: Prof F Antson, Dr J Gordeeva, Dr P Bardy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

University of Birmingham School of Biosciences

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Supervisor: Dr M Soller

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

University of Leeds Faculty of Medicine and Health

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Supervisors: Prof M Wilcox, Dr K Davies, Dr A Buckley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

University of Leeds Faculty of Medicine and Health

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Supervisors: Prof M Wilcox, Prof A O'Neill, Dr J Freeman, Dr I Moura

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

Queen’s University Belfast School of Pharmacy

The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more

Supervisor: Prof M Tunney

Year round applications PhD Research Project Self-Funded PhD Students Only

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Modelling the respiratory microbiome in chronic lung disease and healthy ageing

University of Birmingham Institute of Microbiology and Infection

The Respiratory Microbiome Group seeks to understand the interactions between complex communities of bacteria, fungi and viruses with the human respiratory tract in both disease (acute infections and chronic lung disease) and in health or healthy ageing. Read more

Supervisors: Dr MJ Cox, Dr K Belchamber

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) Determination of the role of viruses in the microbiome of biofilms formed in the ear of patients with otitis media

The University of Manchester Faculty of Biology, Medicine and Health

Otitis media (OM) is a very common infection of the middle ear characterised by redness, swelling and build-up of fluid behind the eardrum. Read more

Supervisors: Prof P Vallely, Prof P Klapper, Prof S Lovell, Mrs JN Nichani

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Systemic infections accelerate tau spreading by promoting glial activation

University of Southampton School of Biological Sciences

Alzheimer’s disease (AD) is a neurodegenerative disease, with a complex biology. In this PhD project, we aim to explore the cellular and molecular mechanisms underlying tau pathology. Read more

Supervisor: Prof J Teeling

17 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigation the role of p62-dependent P-bodies in models of neurodegeneration

University of Plymouth Peninsula Medical School

Applications are invited for a three-year PhD studentship. The studentship will start on 1st Oct 2024. . Project Description. Read more

Supervisors: Dr H Stephenson, Prof S Luo, Dr C Barros

31 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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NIHR Leeds BRC: Using health data to flip the inverse care law in polymyalgia rheumatica

University of Leeds Faculty of Medicine and Health

Polymyalgia rheumatica (PMR) is a common inflammatory musculoskeletal disease affecting older people. It is treated in primary care with long-term corticosteroids (prednisolone). Read more

Supervisors: Dr S Mackie, Prof A Clegg, Dr K Best

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Fully funded PhD student position in structural biology of viruses

Umeå University Chemistry Department

PhD position in the structural biology of viruses. The Department of Chemistry is opening a PhD position in Chemistry with a specialization in structural biology. Read more

Supervisor: Dr M Renner

2 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Developing a novel drug screening platform for schistosomes using the free-living flatworm Schmidtea mediterranea

Kingston University Faculty of Health, Science, Social Care and Education

Schistosoma mansoni is one of three major schistosome species that infect over 240 million people across 70 developing countries, with an additional 0.6 billion at risk of infection. Read more

Supervisor: Dr E Shakir

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Modulation of host immune response by secreted proteins from parasitic worms

University of York York Biomedical Research Institute

Background. To establish chronic infection, parasitic worms manipulate their mammalian hosts’ immune system. This immune modulation is often mediated by excreted or secreted parasite glycoproteins (ES proteins). Read more

Supervisors: Dr CR Crosnier, Dr J Hewitson, Dr A Kay

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of regulatory evolution in phage ecology

The University of Manchester Faculty of Biology, Medicine and Health

The regulation of genes crucially determines the fitness and function of all organisms. This is particularly relevant for bacteriophages, the viruses that infect bacteria, as they rely on a tightly scheduled program for a successful infection. Read more

Supervisors: Dr M Lagator, Dr CI Igler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Developing 3D models to understand how interactions between bacterial biofilm and the host environment impact antimicrobial efficacy in a chronic infected wound

Cardiff Metropolitan University Cardiff School of Sport and Health Sciences

2.8 million people in the UK have a chronic wound which persist for months or years, causing pain, isolation, odour, and decreased mobility; patients with chronic wounds regularly report a deterioration in quality of life. Polymicrobial biofilms are present in greater than 70% of chronic wounds, making effective treatment incredibly challenging. Read more

Supervisors: Dr S Maddocks, Dr M Beeton, Dr R Aicheler, Prof L Robins

Year round applications PhD Research Project Self-Funded PhD Students Only

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Virology: Unique Antiviral Therapy targeting Zika and Related Viruses

University of Leeds Faculty of Medicine and Health

Zika Virus (ZIKV) has emerged as a new mosquito-borne threat to public health after the devastating South American outbreak. Read more

Supervisors: Dr S Griffin, Dr A Kalli, Dr C McKimmie

Year round applications PhD Research Project Self-Funded PhD Students Only

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Adaptive Security Threat Detection for Small Footprint Computing Devices within Industrial Control Systems, Intelligent Homes, Medical Devices & Smart Infrastructure

Anglia Ruskin University ARU School of Computing and Information Science

Research Group: Computing, Informatics and Applications Research Group

Research Group. Cyber Security and Networking Research Group. Proposed supervisory team. Adrian Winckles (adrian.winckles@anglia.ac.uk). Read more

Supervisor: Dr A Winckles

Year round applications PhD Research Project Self-Funded PhD Students Only

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Developing an in silico method for endodontic restoration of human molar teeth

University of Liverpool School of Engineering

The proposed PhD project seeks to address the complex, multi-factorial issue of dental caries and its implications for endodontic treatment. Read more

Supervisors: Dr RR Readioff, Dr A Sharp, Dr N Longridge, Prof FJ Jarad, Dr EM Moawad

Year round applications PhD Research Project Self-Funded PhD Students Only

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Evaluating the Prevalence and Clinical Significance of Genotypic Antibiotic Tolerance Among Important Bacterial Pathogens

University of St Andrews School of Biology

Antibiotic resistance jeopardises our ability to effectively treat bacterial infections, yet it is not the only survival strategy pathogenic bacteria use to evade killing by antibiotics. Read more

Supervisors: Dr J Hobbs, Dr J pearson, Dr B Parcell

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Last chance to apply

Impact of immunity on olfactory circuits in flies and ants

Max Planck Institute for Chemical Ecology International Max Planck Research School

Background. Chemosensation and immunity play a key role to combat and prevent infections with pathogens. Both systems involve highly sophisticated mechanisms which share significant similarities as the two systems are capable of detecting specific cues from infectious microbes in the environment via dedicated receptors. Read more

Supervisors: Dr S Sachse, Dr Y Ulrich

18 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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We have 34 infection model PhD Projects, Programmes & Scholarships

infection model PhD Projects, Programmes & Scholarships

We have 34 infection model PhD Projects, Programmes & Scholarships

CRISPR/Cas9 probing of virulence factors in dermatophytes

4-year PhD Studentship: A novel, bacterial quorum sensor-infused nanocarrier drug delivery system to tackle antimicrobial resistant fungi

Competition and cooperation relationships within human microbial communities.

Mapping CD4+ T cell fate decisions and functional coordination within tissues during infection

Host Pathogen Interaction: Investigating the function of Natural Killer Cells in Bacterial Infection

The impact of nutritional scavenging on host-pathogen interactions, antifungal efficacy and emergence of antifungal resistance

Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

Microbial Community Dynamics and Biocide Susceptibility Profiles in Chronic Wound Biofilms

Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

Modelling the respiratory microbiome in chronic lung disease and healthy ageing

(MRC DTP CASE) Determination of the role of viruses in the microbiome of biofilms formed in the ear of patients with otitis media

Systemic infections accelerate tau spreading by promoting glial activation

Investigation the role of p62-dependent P-bodies in models of neurodegeneration

NIHR Leeds BRC: Using health data to flip the inverse care law in polymyalgia rheumatica

Fully funded PhD student position in structural biology of viruses

Developing a novel drug screening platform for schistosomes using the free-living flatworm Schmidtea mediterranea

Modulation of host immune response by secreted proteins from parasitic worms

The role of regulatory evolution in phage ecology

Developing 3D models to understand how interactions between bacterial biofilm and the host environment impact antimicrobial efficacy in a chronic infected wound

Virology: Unique Antiviral Therapy targeting Zika and Related Viruses

Adaptive Security Threat Detection for Small Footprint Computing Devices within Industrial Control Systems, Intelligent Homes, Medical Devices & Smart Infrastructure

Developing an in silico method for endodontic restoration of human molar teeth

Evaluating the Prevalence and Clinical Significance of Genotypic Antibiotic Tolerance Among Important Bacterial Pathogens

Impact of immunity on olfactory circuits in flies and ants

We have 34 infection model PhD Projects, Programmes & Scholarships

infection model PhD Projects, Programmes & Scholarships

We have 34 infection model PhD Projects, Programmes & Scholarships

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