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We have 21 kidney PhD Projects, Programmes & Scholarships

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kidney PhD Projects, Programmes & Scholarships

We have 21 kidney PhD Projects, Programmes & Scholarships

Endothelial glycocalyx damage as a therapeutic target in sepsis-associated Acute Kidney Injury

Sepsis is the leading cause of acute kidney injury (sAKI), associated with high morbidity and mortality.1,2 Unfortunately, there is no treatment for sAKI, current therapies are nonspecific and supportive of the vital organ systems in the hope the kidney will recover. Read more

Investigating the role of thymosin beta 10 in feline chronic kidney disease

Chronic kidney disease is an extremely common but heterogeneous condition in cats that adversely affects their health and welfare and is the most frequent cause of death in cats over five years of age. Read more

Understanding the role of adiponectin in kidney disease development at a population level

Reduced circulating adiponectin levels are associated with poor outcome in patients with diabetic kidney disease (DKD) (1). Adiponectin has been shown to be protective against the development of DKD in Type 2 diabetic models (2, 3, 4). Read more
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Promoting positive behaviour change in early stage Chronic Kidney Disease (CKD)

The kidneys are specialised organs in the body that filter the body of waste and toxic substances. However, these organs sometimes go wrong and, due to different reasons, lead to dysfunction. Read more

Investigating the link between chronic kidney disease and cardiovascular disease.

Research interests/description of main research theme.  Patients with chronic kidney disease are 40% more likely to develop cardiovascular disease, however, mechanisms driving the cardiovascular pathogenesis are unclear. Read more

Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Preclinical testing of collagen synthesis inhibitors for fibrotic disease

Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

  Research Group: Chemistry and Biosciences
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Glycan sensing technology for early and accurate cancer diagnosis

The Mendes group (https://www.birmingham.ac.uk/research/healthcare-technologies/research/nanoengineering-surface-chemistry/index.aspx) in the School of Chemical Engineering, University of Birmingham welcomes applications from prospective PhD students to conduct work in the area of glycan sensing technology for cancer diagnosis. Read more

Understanding the transcriptional regulation of BK polyomavirus

As obligate intracellular pathogens, viruses rely on host-cell machinery to facilitate their lifecycle. Nuclear-replicating DNA viruses are exposed to factors that can dictate the transcriptional output of the invading viral genome and ultimately influence infection outcome. Read more
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