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We have 104 pathogens PhD Projects, Programmes & Scholarships

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pathogens PhD Projects, Programmes & Scholarships

We have 104 pathogens PhD Projects, Programmes & Scholarships

Discovery and functional investigation of the shared molecular mechanisms of host immunoregulation by the pathogens that cause malaria and sepsis.

Infectious diseases cause enormous humanitarian and economic burdens worldwide. Designing interventions that prevent, cure, or control many infections is difficult because pathogens have evolved sophisticated ways of subverting host immunity. Read more

Identify novel approaches to combat multi drug resistant pathogens

Our research is focused on recalcitrant ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, andEnterobacter species) pathogens; especially hard-to-treat clinical isolates involved in multidrug resistance, biofilm infections and persistence. Read more

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Unlocking immune cells with tick-borne pathogens

In this project we will use tick-borne pathogenic bacteria as a molecular tool-kit for unlocking immune cells. These discoveries will help us combat tick-borne disease and provide a basis for manipulating immune cells, impacting on a wide range of diseases. Read more

How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Optimizing phage-antibiotic-synergies to kill bacterial pathogens

Phage therapy, the use of viruses that only infect bacterial cells and kill them, is a promising potential solution to the antimicrobial resistance crisis that is threatening modern medicine1. Read more

Plant Nematology

Introduction. The Plant Nematology Laboratory is an internationally recognised group working to understand the interactions between parasitic nematodes and their plant hosts. Read more

Predicting the Evolution of Influenza and SARS-CoV-2 Viruses

Our research focus is to design and develop analytical, computational, and mathematical methods to understand the fundamental processes that govern the evolution of influenza and SARS-CoV-2 viruses. Read more

Regulation of virulence and biofilm formation by quorum sensing and the "stress alarmone" ppGpp in gram-negative pathogenic bacteria.

We are investigating the complex interplay between cell-cell signalling (quorum sensing), microbial lifestyle (i.e., free-living planktonic cultures vs sessile biofilm communities), growth phase and virulence in gram-negative bacteria. Read more

Manipulation of neuroimmune responses and behaviour by infectious agents

This project is available exclusively to self-funded students who wish to commence study for a PhD in the academic year 2023/24. The project focuses on how infectious agents modify the individuals that they infect and how neuroimmune responses to infection moderate behaviour changes in warm-blooded animals and humans. Read more

Understanding the soil microbiome under controlled light conditions

Our research group is working within a consortium that is testing semi-transparent solar installations on crop growth-houses, to enhance biological and financial resilience in protected farming. Read more

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