peptides PhD Projects, Programmes & Scholarships

PhD in Chemistry: Computer simulation of metal-amyloid interaction and its role in plaque formation

Cardiff University Cardiff School of Chemistry

Alzheimer’s disease is one of the greatest healthcare challenges facing 21st century society. AD is associated with formation of fibrils and plaques in brain tissue that impair proper functioning of neurons. Read more

Supervisor: Prof J Platts

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design and engineering of peptides and proteins to create artificial metalloenzymes

Cardiff University Cardiff School of Chemistry

The Rhys lab is an exciting new lab looking to recruit new students to design and engineer peptides and proteins for new applications (rhyslab.com). Read more

Supervisor: Dr G Rhys

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the interactions of incretin hormone mimetics with hypothalamo-neurohypophysial system arginine vasopressin and oxytocin release

University of Bristol Bristol Medical School

Our research focus over decades has been the osmoregulatory function of a special collection of neurones in a part of the brain called the hypothalamus. Read more

Supervisor: Prof D Murphy

Year round applications PhD Research Project Self-Funded PhD Students Only

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PhD in Supramolecular Chemistry: Metallo-Peptide Cages - Peptides as Adaptable Building Blocks in Metal-Organic Supramolecular Self-Assembly

King’s College London Department of Chemistry

We are a synthetic chemistry group working in supramolecular and biological chemistry, and nanotechnology. We work in the Francis Crick Institute in London, and at King's College London - find more details at https://www.mcternanresearchgroup.com/. Read more

Supervisor: Dr CMT McTernan

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Maastricht University Cardiovascular Research Institute Maastricht (CARIM)

Applications can only be submitted via our website. The specific position for Doctoral Candidate 6 (DC6) in the consortium, which is part of Work Package 2 (WP2), aims. Read more

Supervisor: Dr G Nicolaes

30 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Unravelling the Intricacies of Stress Hormone Regulation

University of Reading Department of Biomedical Sciences

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

Supervisor: Dr A B Bicknell

Year round applications PhD Research Project Self-Funded PhD Students Only

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ThAnoS: thiopeptide antibiotics biosynthesis (GHILAROV_J24DTP)

John Innes Centre Graduate Programme

Background. The acute problem of antimicrobial resistance incentivises us to develop innovative approaches to antibiotic discovery & production. Read more

Supervisor: Dr D Ghilarov

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Biomedicines from the hidden animal world: The microbiome and immune system of micro-metazoans and the potential for antimicrobial discovery

University of Plymouth Faculty of Health

Applications are invited for a three-year PhD studentship. The studentship will start on 1 October 2024. Project Description. Read more

Supervisor: Dr M Banton

22 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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An Interdisciplinary Approach to Developing of Macrocyclic Inhibitors of the MAPK Pathway

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team: Prof Ali Tavassoli . Project Description. We are seekign an outstanding chemistry student with an interest in chemical biology to work on a project to develop cyclic peptide inhibitors of a protein-protein interaction that is heavily implicated in the development and growth of tumours. . Read more

Supervisor: Prof A Tavassoli

31 August 2024 PhD Research Project Competition Funded PhD Project (European/UK Students Only)

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Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation

The University of Manchester Faculty of Biology, Medicine and Health

This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more

Supervisors: Dr HS Shokr, Dr CT Tapeinos, Dr H Aojula

Year round applications PhD Research Project Self-Funded PhD Students Only

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How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

The University of Manchester Department of Physics and Astronomy

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Supervisor: Prof J Lu

28 June 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

Queen’s University Belfast School of Pharmacy

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

Supervisor: Dr G Laverty

Year round applications PhD Research Project Self-Funded PhD Students Only

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Maximising the potential of fragmented bone to gain new insights into the coexistence of Neanderthals and Homo sapiens in Central and Southeast Europe.

University of Reading School of Archaeology

Applications are invited for a research studentship in the field of archaeological science (proteomics, near-infrared spectroscopy, radiocarbon dating) leading to the award of a PhD degree. Read more

Supervisor: Dr K J Ruebens

31 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Developing multifunctional biomaterials: an anti-infective and pro-endothelialisation polymer graft

University of Strathclyde Pure and Applied Chemistry

This project is one of 14 four year PhD Studentships funded by Medical Research Scotland (MRS) (https://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and External Partner Organisation (EPO). Read more

Supervisor: Dr K.H.A Lau

1 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more

Supervisors: Dr M Hussain, Dr T Nasim, Prof MR Boyett

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using chemical-genetics to inhibit and characterise “undruggable” enzymes

University of Dundee School of Medicine

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Developing the next generation of MALDI mass spectrometry

University of Reading School of Chemistry & Food

Project Overview: This project aims to make step changes in mass spectrometry (MS) by combining the advantages of MALDI with those of electrospray… Read more

Supervisor: Prof R K Cramer

31 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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‘Payload-Releasing Electrophiles’ – a new disease-selective delivery strategy for diagnostics and therapeutics

University of Leicester Department of Chemistry

Graduate Teaching Assistantship. This is a Graduate Training Assistantship (GTA), which means that you will be required to do some teaching, particularly lab demonstrating, as part of your training. Read more

Supervisors: Dr R Hopkinson, Dr K Tanaka

22 April 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Microfluidic Encapsulation of biologics into Nanomedicines

Queen’s University Belfast School of Pharmacy

Progress in drug design has led to the development of new peptides, proteins, and drug molecules. However, the limited ability to deliver selectively these molecules at well-defined dosing regimens and without invoking drug-resistance remains a significant challenge. Read more

Supervisor: Prof D Lamprou

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Painting living matrices: developing tools for spatio-temporal patterning of biomaterials

University of Leeds Faculty of Engineering and Physical Sciences

Research Group: School of Physics and Astronomy

This PhD project opportunity is part of an ambitious European Research Council research project which aims to exploit protein networks for future applications. Read more

Supervisors: Prof L Dougan, Prof D B Brockwell, Prof N Kapur

31 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Development of one- and two-dimensional chromatographic methods coupled to mass spectrometry for proteomic analyses and analysis of protein biopharmaceuticals

Charles University Faculty of Pharmacy

Faculty of Pharmacy, Charles University, Department of Analytical Chemistry . Read more

Supervisors: Assoc Prof H Sklenářová, Dr J Lenčo

30 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

University of Liverpool Institute of Life Course and Medical Sciences

Immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) affect millions of people worldwide and cause debilitating and disabling musculoskeletal disease. Read more

Supervisors: Dr HL Wright, Prof MJ Peffers

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting Ras palmitoylation for the treatment of cancer

University of Dundee School of Medicine

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Supervisor: Dr N Fraser

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Engineering extracellular vesicles/exosomes for the treatment of ocular disease

Cardiff University Cardiff School of Optometry & Vision Sciences

Extracellular vesicles, also referred to as exosomes, are membrane‐bound particles containing huge numbers of proteins as well as genetic material in the form of RNA (mRNA and miRNA). Read more

Supervisor: Dr B Mead

5 August 2024 PhD Research Project Self-Funded PhD Students Only

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Genetic Engineering of Immune Effector Cells for CAR therapies using a Peptide Technology

Queen’s University Belfast School of Pharmacy

Chimeric antigen receptor (CAR)-T therapies have demonstrated remarkable treatment outcomes and several CAR-T therapies now approved for treatment of haematological malignancies. Read more

Supervisors: Dr E McErlean, Prof H McCarthy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

University of Portsmouth School of Pharmacy and Biomedical Sciences

Applications are invited for a self-funded, 3 year full-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. Read more

Supervisors: Dr R Hadianamrei, Dr S Hafizi

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding and preventing the denaturation of proteins on surfaces in manufacture, storage and delivery of biotherapeutics

The University of Manchester Department of Materials

Protein and peptide therapeutics are pharmaceutical drug treatments derived from natural sources. They are applied to a range of diseases from diabetes to novel cancer therapies. Read more

Supervisors: Dr A Thomas, Prof A Saiani

Year round applications PhD Research Project Self-Funded PhD Students Only

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Engineering Ice-Binding Proteins

The University of Manchester Department of Chemistry

Ice-binding proteins are produced by extremophiles to help them survive in the worlds coldest places. They have many potential applications, from the storage of cells/tissue to transport infrastructure. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding L1 ORF1p and Pin1 interaction to exploit it as a therapeutic strategy for liver cancer (ref: SF22/HLS/APP/SHUKLA)

Northumbria University Faculty of Health and Life Sciences

Primary liver cancer, predominantly hepatocellular carcinoma (HCC), is the 4th commonest cause of cancer death globally. Read more

Supervisor: Dr R Shukla

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 31 peptides PhD Projects, Programmes & Scholarships

peptides PhD Projects, Programmes & Scholarships

We have 31 peptides PhD Projects, Programmes & Scholarships

PhD in Chemistry: Computer simulation of metal-amyloid interaction and its role in plaque formation

Design and engineering of peptides and proteins to create artificial metalloenzymes

Investigating the interactions of incretin hormone mimetics with hypothalamo-neurohypophysial system arginine vasopressin and oxytocin release

PhD in Supramolecular Chemistry: Metallo-Peptide Cages - Peptides as Adaptable Building Blocks in Metal-Organic Supramolecular Self-Assembly

In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Unravelling the Intricacies of Stress Hormone Regulation

ThAnoS: thiopeptide antibiotics biosynthesis (GHILAROV_J24DTP)

Biomedicines from the hidden animal world: The microbiome and immune system of micro-metazoans and the potential for antimicrobial discovery

An Interdisciplinary Approach to Developing of Macrocyclic Inhibitors of the MAPK Pathway

Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation

How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

Maximising the potential of fragmented bone to gain new insights into the coexistence of Neanderthals and Homo sapiens in Central and Southeast Europe.

Developing multifunctional biomaterials: an anti-infective and pro-endothelialisation polymer graft

Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

Using chemical-genetics to inhibit and characterise “undruggable” enzymes

Developing the next generation of MALDI mass spectrometry

‘Payload-Releasing Electrophiles’ – a new disease-selective delivery strategy for diagnostics and therapeutics

Microfluidic Encapsulation of biologics into Nanomedicines

Painting living matrices: developing tools for spatio-temporal patterning of biomaterials

Development of one- and two-dimensional chromatographic methods coupled to mass spectrometry for proteomic analyses and analysis of protein biopharmaceuticals

Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

Targeting Ras palmitoylation for the treatment of cancer

Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

Engineering extracellular vesicles/exosomes for the treatment of ocular disease

Genetic Engineering of Immune Effector Cells for CAR therapies using a Peptide Technology

Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

Understanding and preventing the denaturation of proteins on surfaces in manufacture, storage and delivery of biotherapeutics

Engineering Ice-Binding Proteins

Understanding L1 ORF1p and Pin1 interaction to exploit it as a therapeutic strategy for liver cancer (ref: SF22/HLS/APP/SHUKLA)

We have 31 peptides PhD Projects, Programmes & Scholarships

peptides PhD Projects, Programmes & Scholarships

We have 31 peptides PhD Projects, Programmes & Scholarships

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