We have 49 protein purification PhD Projects, Programmes & Scholarships

The research group of Dr. Katja Zieske invites applications for a. PhD position (f/m/d). for the project. Biophotonic Characterization of Living matter from the Bottom-Up. Read more

Supervisor: Dr KZ Zieske

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Waste-to-protein recovery through protein separation and purification

King’s College London School of Natural & Mathematical Sciences

The plant-sourced and animal-sourced proteins are resource-demand and carbon-intensive. This combined with increasing protein demands highlight the complex challenge on providing protein security. Read more

Supervisors: Dr M Guo, Prof C Lorenz

1 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Better together: constructing tuneable fluorescent protein sensors for cellular imaging of protein-protein interactions

Cardiff University Cardiff School of Biosciences

Project Description. Protein-protein interactions (PPIs) commonly occur in biology with ~650,000 contributing to processes critical to human life. Read more

Supervisors: Prof D Jones, Dr PD Watson, Dr G Menzies, Dr R Clarkson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Membrane protein-metabolite interactions important in mitochondrial energy metabolism for burning fat as heat (CRICHTON_U24DTP)

University of East Anglia Norwich Medical School

Primary supervisor - Dr Paul Crichton . Secondary supervisor - Prof. Tom Clarke (UEA) . Mitochondria in our cells harness energy through the breakdown of nutrients to produce ATP through oxidative phosphorylation. Read more

Supervisor: Dr P Crichton

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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From structure and dynamics to controlled gel formation of sustainable food proteins from plant seeds

Malmö University Department of Biomedical Science

Research Project. The PhD will be enrolled at the Division of Physical Chemistry at Lund University due to a change of affiliation of the supervisor Felix Roosen-Runge. Read more

Supervisor: Dr F Roosen-Runge

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

University of Sheffield School of Biosciences

Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more

Supervisor: Dr C Guo

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identification and characterisation of bacteriocins from environmental samples active against strains of Clostridium difficile.

University of Nottingham School of Life Sciences

Clostridiodes difficile is a cause of neonatal enteritis in livestock such as pigs, cattle and horses. Affected animals develop respiratory problems, abdominal distention and bloody diarrhoea leading to weight loss and in extreme cases mortality. Read more

Supervisors: Dr C Penfold, Dr K Winzer

Year round applications PhD Research Project Self-Funded PhD Students Only

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How do RNA-binding proteins control splice site selection? A multi-disciplinary approach

University of Leicester Molecular and Cell Biology

Almost every protein-coding gene in vertebrates can and does express multiple proteins. This is achieved primarily by RNA splicing, which is an essential step in gene expression in mammals and generates incredible diversity. Read more

Supervisors: Prof I Eperon, Prof A Hudson, Dr C Dominguez

Year round applications PhD Research Project Self-Funded PhD Students Only

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Unlocking immune cells with tick-borne pathogens

University of Bristol Faculty of Health Sciences

In this project we will use tick-borne pathogenic bacteria as a molecular tool-kit for unlocking immune cells. These discoveries will help us combat tick-borne disease and provide a basis for manipulating immune cells, impacting on a wide range of diseases. Read more

Supervisors: Dr I Cadby, Dr J Mann, Dr E Ballou

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Investigating the interaction of La related proteins with colliding ribosomes

The University of Manchester Faculty of Biology, Medicine and Health

Translation of mRNA into proteins is a critical cellular biological process for all life. This requires ribosomes to act with an array of translation factors to decode mRNA sequences. Read more

Supervisors: Prof G D Pavitt, Dr A Roseman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Obtaining an integrated understanding of oncogenic RAS signalling

University of Leicester Molecular and Cell Biology

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more

Supervisor: Dr K Tanaka

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Supervisors: Dr M Young, Dr J Parker

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding control of genome folding by cohesin

University of Leicester Molecular and Cell Biology

Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more

Supervisors: Prof D Panne, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Fully funded PhD student position in structural biology of viruses

Umeå University Chemistry Department

PhD position in the structural biology of viruses. The Department of Chemistry is opening a PhD position in Chemistry with a specialization in structural biology. Read more

Supervisor: Dr M Renner

2 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Molecular dissection of horizontal gene transfer mechanisms in mycobacteria

University of Leicester Molecular and Cell Biology

A fully funded PhD position is available within the lab of Dr Abhinav KV at Leicester Institute of Structural and Chemical Biology (LISCB), University of Leicester, UK to carry out structural studies on large macromolecular machines that undertake horizontal gene transfer (HGT) in mycobacteria. Read more

Supervisors: Dr A Koyamangalath Vadakkepat , Prof J Schwabe

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

The University of Manchester Department of Physics and Astronomy

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Supervisor: Prof J Lu

28 June 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Structural basis of two-component system signaling

Max Planck Institute for Chemical Ecology International Max Planck Research School

Background: . As bacteria explore new habitats, go to war with competitors or collaborate against common enemies, they rely heavily on intra- and interspecies communication and precise molecular scouting of their environment. Read more

Supervisors: Prof UH Hellmich, Prof S.E.O. O'Connor

18 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Unravelling the mechanisms behind plant stress sensing

University of Oxford Department of Biology

Agricultural production and food security are severely threatened by the loss of arable land and climate change, with increasingly harsher droughts, floods, and heat waves reducing crop productivity by more than 50%. Read more

Supervisors: Dr J Bolla, Dr EBG Baena-Gonzalez

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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PhD in Chemistry: Improving protease performance

Cardiff University Cardiff School of Chemistry

An industrially funded studentship is available in the research group of Regius Professor Graham Hutchings and Professor Stuart Taylor together with Professor Nigel Richards to work on protease enzymes. Read more

Supervisors: Prof G J Hutchings, Prof S Taylor

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Targeting Ras palmitoylation for the treatment of cancer

University of Dundee School of Medicine

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Supervisor: Dr N Fraser

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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4-year PhD Studentship: Combatting bacterial zoonoses through multi-disciplinary studies of virulence factors

University of Bristol Bristol Veterinary School

Vector-borne diseases, including bacterial zoonoses, pose a significant threat to human and animal health and to livestock industries, particularly in low and middle-income countries. Read more

Supervisor: Dr T Cogan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Fully-funded PhD in Biology EPSRC iCASE with FUJIFILM Diosynth Biotechnologies (FDBK): Development of modular chromatography strategies for the straight through purification of biotherapeutic recombinant proteins from E.coli

University of York Department of Biology

Lead supervisor: Dr Michael Plevin (Department of Biology). Co-supervisors: Dr John Oyekan (Department of Computer Science) and Christopher Fox (Fujifilm Diosynth Biotechnologies). Read more

Supervisor: Dr M Plevin

22 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

Supervisors: Dr H O'Hare, Dr N Garton

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more

Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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‘Payload-Releasing Electrophiles’ – a new disease-selective delivery strategy for diagnostics and therapeutics

University of Leicester Department of Chemistry

Graduate Teaching Assistantship. This is a Graduate Training Assistantship (GTA), which means that you will be required to do some teaching, particularly lab demonstrating, as part of your training. Read more

Supervisors: Dr R Hopkinson, Dr K Tanaka

22 April 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Building new nano-biosensors for healthcare: Linking biology to the world of carbon nanotechnology through synthetic biology

Cardiff University Cardiff School of Biosciences

Project Descriptions. Proteins are nature’s very own molecular machines carrying out functions ranging from catalysis to molecular recognition to energy conversion. Read more

Supervisors: Prof D Jones, Dr M Palma, Dr WK Kelton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using lipid nano-particles to study G-protein-coupled receptors (GPCRs).

Coventry University Centre for Health and Life Sciences

This exciting PhD project in the laboratory of Professor Mark Wheatley, Professor of Biochemical Pharmacology is a joint PhD between Coventry University and Stellenbosch University with the student being registered for a PhD at both universities. Read more

Supervisor: Prof M Wheatley

6 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology

Ever wondered how nature maintains balance of gene expression between sex chromosomes? Well, the 46th chromosome of XX females, the second X, has to be switched off. Read more

Supervisors: Dr Y Markaki, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy

Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 49 protein purification PhD Projects, Programmes & Scholarships

protein purification PhD Projects, Programmes & Scholarships

We have 49 protein purification PhD Projects, Programmes & Scholarships

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