We have 160 rna PhD Projects, Programmes & Scholarships

Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more

Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Defining the molecular mechanisms of leukaemia chemotherapies

The University of Manchester Faculty of Biology, Medicine and Health

Chemotherapies are usually the backbone of cancer treatment for either curative or palliative patient care. Multiple therapies can be used for the same disease, with the choice of drug dependent on parameters such as the patient’s age and fitness. Read more

Supervisors: Dr JK Knight, Dr K Batta, Dr D Wiseman

Year round applications PhD Research Project Self-Funded PhD Students Only

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cGAS-STING involvement in respiratory viral infections

Cardiff University Cardiff School of Medicine

This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£42,000 total). Read more

Supervisor: Dr M Triantafilou

31 May 2024 PhD Research Project Self-Funded PhD Students Only

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Application and development of bioinformatics and network theory methods in cardiovascular disease research and pharmacovigilance

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

To be able to discover novel drug targets we aim to develop software based on network theoretic approaches that are capable to identify mediators and pathways involved in the pathomechanism of various cardiovascular diseases by the analysis of datasets assessed with high throughput molecular biological techniques (e.g. Read more

Supervisor: Dr B Ágg

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Computational RNA Biology PhD: CRISPR functional genomics and long-read nanopore sequencing

Garvan Institute of Medical Research Genomics and Cellular Biology

The field of CRISPR technology is ushering in a new era in our understanding of the root causes of diseases. Read more

Supervisor: Dr R Weatheritt

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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MSc By Research: Unravelling the mechanisms controlling anterior eye development

Aberdeen University School of Medicine, Medical Sciences & Nutrition

The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more

Supervisors: Prof L Erskine, Prof N Vargesson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structure-function analysis of a plant virus RNA transport protein

The James Hutton Institute Postgraduate Training

Background. Plants form the basis of human nutrition but crop yields are increasingly under threat from climate change and the associated shifts in pathogen distributions. Read more

Supervisors: Dr J Tilsner, Dr J Bos

14 June 2024 PhD Research Project Competition Funded PhD Project (European/UK Students Only)

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Controlling greenhouse gas emissions by targeting bacterial G-quadruplex DNA/RNA structures (GATES_U24DTP)

University of East Anglia School of Biological Sciences

Primary supervisor - Dr Andrew Gates . Secondary supervisor - Dr Yiliang Ding (JIC) . As well as carbon dioxide (CO2), other important climate-active gases are known to drive global warming. Read more

Supervisor: Dr A Gates

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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How do RNA-binding proteins control splice site selection? A multi-disciplinary approach

University of Leicester Molecular and Cell Biology

Almost every protein-coding gene in vertebrates can and does express multiple proteins. This is achieved primarily by RNA splicing, which is an essential step in gene expression in mammals and generates incredible diversity. Read more

Supervisors: Prof I Eperon, Prof A Hudson, Dr C Dominguez

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of RNA secondary structure in plant transposable elements

Durham University Department of Biosciences

Transposable elements (TEs), often referred to as jumping genes, are mobile genetic elements that can be found ubiquitously across the tree of life. Read more

Supervisor: Dr J Cho

17 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Ensuring a social license to operate for the use of RNA based bio pesticides for agriculture

Curtin University Curtin Institute for Energy Transition

The Australia Research Council (ARC) Industrial Transformation Research Program (ITRP) Research Hub for Sustainable Crop Protection is taking on the global challenge of transforming crop protection technology by delivering non-GM, non- toxic RNAi based fungicides for specific fungal diseases of crops. Read more

Supervisor: Prof PA Ashworth

24 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Investigating the role of RNA dependent DNA repair in childhood cancer

University of Dundee School of Medicine

Damage to our genetic material DNA is responsible for a wide range of human diseases including neurodegenerative diseases, haematological diseases, immune deficiencies, early ageing and cancers. Read more

Supervisor: Prof K Hiom

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Self-funded MSc R- The mechanisms driving heterogeneity and stemness during cellular transformation.

University of Bristol School of Cellular and Molecular Medicine

The mechanisms driving heterogeneity and stemness during cellular transformation. Read more

Supervisor: Dr A Essafi

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded PhD- The mechanisms driving heterogeneity and stemness during cellular transformation.

University of Bristol School of Cellular and Molecular Medicine

The mechanisms driving heterogeneity and stemness during cellular transformation. Read more

Supervisor: Dr A Essafi

Year round applications PhD Research Project Self-Funded PhD Students Only

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Short and long-term genetic and behavioural consequences of traumatic brain injury in fruit flies

University of Leicester Department of Genetics and Genome Biology

General background . How many fingers am I holding up? What day of the week is it? Follow my finger? These three questions are designed to test your sensory, memory and motor neural abilities following an accident; all three systems are affected by a severe deceleration of your brain. Read more

Supervisors: Dr B Warren, Dr E Rosato, Dr R Feuda

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology

Ever wondered how nature maintains balance of gene expression between sex chromosomes? Well, the 46th chromosome of XX females, the second X, has to be switched off. Read more

Supervisors: Dr Y Markaki, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular characterization of Sam68-driven cytoskeletal reorganization

University of Leicester Molecular and Cell Biology

The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more

Supervisors: Dr C Dominguez, Prof A Fry

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Human Genetics, Genomics and Disease: Understanding how nuclear architecture affects neuronal function in health and disease

University of Edinburgh College of Medicine and Veterinary Medicine

Research Group: MRC Human Genetics Unit

Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center Berlin Institute for Medical Systems Biology, Berlin, Germany. Read more

Supervisor: Prof N Gilbert

19 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Control and inhibition of virus replication

University of Leeds Faculty of Biological Sciences

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more

Supervisor: Dr A.K Tuplin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

University of Liverpool Institute of Life Course and Medical Sciences

Immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) affect millions of people worldwide and cause debilitating and disabling musculoskeletal disease. Read more

Supervisors: Dr HL Wright, Prof MJ Peffers

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the role of spliceosome gene mutations in disease

The University of Manchester Faculty of Biology, Medicine and Health

The DNA of a cell is copied into a pre-messenger RNA (pre-mRNA) that the cell uses as a template for protein production. Some of the information contained in DNA is not required for making proteins, therefore, unwanted information must be removed before a protein is made. Read more

Supervisors: Prof R O'Keefe, Prof B Newman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Engineering extracellular vesicles/exosomes for the treatment of ocular disease

Cardiff University Cardiff School of Optometry & Vision Sciences

Extracellular vesicles, also referred to as exosomes, are membrane‐bound particles containing huge numbers of proteins as well as genetic material in the form of RNA (mRNA and miRNA). Read more

Supervisor: Dr B Mead

5 August 2024 PhD Research Project Self-Funded PhD Students Only

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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy

Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Novel disease genes in brain development and decline

University of Otago Department of Biochemistry

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Supervisor: Assoc Prof L Bicknell

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology

More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more

Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson

Year round applications PhD Research Project Self-Funded PhD Students Only

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A deep-learning approach to genomic regulation of tissue-specific alternative splicing

The University of Manchester Faculty of Biology, Medicine and Health

Each human gene is a blueprint for multiple distinct RNA transcripts that can be produced in differing quantities based on the localisation of the transcribing… Read more

Supervisors: Dr JE Eales, Prof T Papamarkou

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of integrated microfluidic chips for making mRNA nanomedicines

University of Adelaide School of Chemical Engineering

Project. Recent mRNA vaccine success has heralded a new era of RNA nanomedicines. We are pleased to announce a fully funded PhD position with a scholarship focused on the development of integrated microfluidic chips for making mRNA nanomedicines. Read more

Supervisor: Prof CXZ Zhao

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Transcriptome homeostasis in cellular ageing and cancer

Queen Mary University of London Institute of Dentistry

Project Summary. We have previously established the oncogenic mechanisms of the transcription factor FOXM1 in perturbation of genome stability (1, 2), epigenome (3, 4) and adult progenitor epithelial stem cell proliferation (5). Read more

Supervisor: Dr M T Teh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Transgenerational epigenetic consequences of pollution exposure.

University of Leicester Department of Genetics and Genome Biology

Project background. Environmental insults such as pollution can cause transgenerational negative health outcomes in both wild animal populations and humans. Read more

Supervisor: Dr H Marshall

Year round applications PhD Research Project Self-Funded PhD Students Only

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(BRC) Nailfold capillary imaging in the idiopathic inflammatory myopathies (Non-Clinical)

The University of Manchester Faculty of Biology, Medicine and Health

The idiopathic inflammatory myopathies (IIMs) are rare conditions characterised by distinct clinical subtypes and varied multisystem involvement. Read more

Supervisors: Dr A Murray, Dr H Chinoy, Dr J Lamb

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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We have 160 rna PhD Projects, Programmes & Scholarships

rna PhD Projects, Programmes & Scholarships

We have 160 rna PhD Projects, Programmes & Scholarships

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