toxicity PhD Projects, Programmes & Scholarships

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Understanding the emissions and toxicity from domestic burning in the UK

University of York Department of Chemistry

Poor air quality is the biggest environmental factor contributing to premature mortality globally. Read more

Supervisors: Prof J Hamilton, Dr A R Rickard

1 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Determining the dietary accumulation and toxicity of nanoplastics and co-contaminants (zinc oxide nanomaterials) in fish

University of Plymouth Faculty of Health

Applications are invited for a four-year PhD studentship. The studentship will start on 01 October 2024. Project Description. Plastic pollution represents a global environmental challenge. Read more

Supervisor: Dr N Clark

1 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Uncovering the mechanisms of cryoprotectant toxicity and improving cryopreservation protocols

University of Birmingham Institute of Inflammation and Ageing

Cryopreservation is the process of placing cells, organs or even whole organisms at low temperatures so that they remain in a state of suspended animation and function is preserved. Read more

Supervisor: Prof JP Magalhaes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Manganese is essential to human health and development. However, excess manganese is neurotoxic causing manganism, a neurodegenerative disorder characterised by dystonia-parkinsonism. Read more

Supervisors: Dr K Tuschl, Dr P Mills, Dr WH Heywood

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Leveraging metabolomics to reduce copper toxicity in dairy cattle

Harper Adams University Department of Agriculture and Environment

Successful candidates will receive a yearly stipend (paid monthly) set at the UKRI rate - for 2024/5 this will be £19,237. Read more

Supervisor: Dr J McCaughern

17 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

University of Liverpool Department of Pharmacology and Therapeutics

Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Read more

Supervisors: Dr M Cross, Prof C Goldring

Year round applications PhD Research Project Self-Funded PhD Students Only

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Alpha-synuclein amyloid in Parkinson's disease: using Nanoinjection as a tool to study alpha-synuclein amyloid toxicity inside neurons

University of Leeds Faculty of Biological Sciences

Intraneuronal inclusions known as Lewy bodies are a hallmark of Parkinson’s disease. Amyloid fibrils formed by the misfolding of alpha-synuclein are the principal component of Lewy Bodies. Read more

Supervisors: Dr E W Hewitt, Prof S E Radford, Dr P Actis

Year round applications PhD Research Project Self-Funded PhD Students Only

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Analysing the role of statins in cardiovascular protection

University of Liverpool Department of Pharmacology and Therapeutics

Drug-induced cardiovascular toxicity is a major problem affecting a number of cancer chemotherapy drugs (Cross et al., 2015). Read more

Supervisors: Dr M Cross, Dr B Wilm, Dr AM Mondru

Year round applications PhD Research Project Self-Funded PhD Students Only

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Metal-based Antimicrobials: Tackling Resistance with Catalytic Redox Stressors

University of York York Biomedical Research Institute

Background. New antibiotics are urgently needed to combat the widespread rise in resistance. However, only very few of the drug candidates in clinical development represent new structural classes. Read more

Supervisors: Prof A-K Duhme-Klair, Prof G Thomas, Prof G Barlow

Year round applications PhD Research Project Self-Funded PhD Students Only

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Fully funded studentship in Plastivore Plasticity: characterising metabolic flexibility in an emerging biotechnological system to manage plastic waste

Brunel University London Life Sciences

Applications are invited from high-calibre and passionate students seeking to pursue an exciting career in analytical and environmental science research, with a focus to tackle a growing concern with respect to managing plastic waste. Read more

Supervisor: Dr TM Miller

10 June 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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Development of antibody-drug conjugates (ADCs) for oncology indications

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more

Supervisors: Prof K Pors, Dr Muhammad Wahajuddin, Prof R Falconer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Hepatic Models to personalise cancer chemotherapy

University of Liverpool Department of Pharmacology and Therapeutics

The most commonly used chemotherapy regimens for colorectal cancer with liver metastases are oxaliplatin combined with 5-FU and leucovorin, i.e. Read more

Supervisors: Prof C Goldring, Dr A Chadwick, Prof IC Copple, Dr S Pushpakom

Year round applications PhD Research Project Self-Funded PhD Students Only

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Shell-doped quantum dots as smart “on-off” catalysts for thermally sensitive organic transformations

Kingston University Faculty of Health, Science, Social Care and Education

Quantum dots (QDs) are photoluminescent nanoparticles which reside at the cutting edge of opto-electronic device development, with the 2023 Nobel prize in chemistry awarded to 3 of the most prominent scientists in the field. Read more

Supervisor: Dr J Bear

Year round applications PhD Research Project Self-Funded PhD Students Only

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Harnessing Breast Cancer Therapy: Innovative Formulation Strategies for Repurposing Medicines to Overcome Resistance

Kingston University Faculty of Health, Science, Social Care and Education

Background. Research in the Kadri group focuses on developing innovative chemical approaches for the discovery of novel therapeutics to address unmet global health needs. Read more

Supervisor: Dr H Kadri

Year round applications PhD Research Project Self-Funded PhD Students Only

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Modification of antibiotics to improve efficacy / safety

Kingston University Faculty of Health, Science, Social Care and Education

With increasing concern over antibiotic resistance, antibacterial agents such as chloramphenicol and colistin, which have frequently been passed over in the past because of concerns over toxicity, are now becoming more important to tackle resistant bacterial strains. . Read more

Supervisor: Dr I Beadham

Year round applications PhD Research Project Self-Funded PhD Students Only

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Enhancing PMMA Bone Cement Performance and Biocompatibility using Metal-Organic Frameworks

University of Portsmouth School of Pharmacy and Biomedical Sciences

Applications are invited for a self-funded, 3 year full-time or 6 year part-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Sciences and will be supervised by Dr Marta Roldo and Professor Paul Cox. Read more

Supervisors: Dr M Roldo, Prof P Cox

Year round applications PhD Research Project Self-Funded PhD Students Only

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Degradable and resorbable polymeric cryoprotectants

The University of Manchester Department of Chemistry

Extremophiles have evolved to survive in the world’s coldest environments, through the production of specialised macromolecules, such as antifreeze proteins and ‘ice nucleating proteins. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Ultra-long coherence time diamond nanoparticles

Cardiff University Cardiff School of Physics and Astronomy

Cardiff Diamond Foundry / Cardiff University is seeking an enthusiastic PhD student to study the properties of diamond nanoparticles and their application in quantum technologies (especially healthcare). Read more

Supervisors: Prof O Williams, Dr N Gunasekar

24 June 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Novel nanocomposites based on green resin chemistries reinforced with 2D nanofillers and natural fibres

University of Sunderland Faculty of Technology

Applications are invited for a fully funded studentship to start in October 2024. About the project. Nanocomposites based on thermosetting resin matrices are one of the most promising lightweight materials to replace metal components and reduce energy and greenhouse gas emissions in the transport industries. Read more

Supervisor: Dr P Karagiannidis

14 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Linking metabolism and metal resistance in pathogenic bacteria (SULLIVANM_U24AMSSCI)

University of East Anglia School of Biological Sciences

Primary supervisor - Dr Matthew Sullivan. Group B Streptococcus (GBS) is an effective pathogen of humans and animals and is well known as the leading cause of often-fatal infections in newborn infants. Read more

Supervisor: Dr MS Sullivan

31 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Designing Peptide hydrogels as vehicles for targeted and localised in-vivo therapeutics delivery

The University of Manchester Faculty of Biology, Medicine and Health

One of the key engineering challenges in the life-science and biomedical sectors is the design and manufacturing of bespoke hydrogels for 3D cell culture, tissue engineering and cell/drug delivery. Read more

Supervisors: Prof A Saiani, Dr K Finegan

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Delivery and misdelivery of outer membrane proteins to the BAM complex using cryoEM

University of Leeds Faculty of Biological Sciences

The BAM complex folds membrane proteins into the outer membrane of Gram-negative bacteria, proteins whose functions are essential for bacterial viability, pathogenicity and virulence. Read more

Supervisors: Prof N A Ranson, Prof S E Radford

Year round applications PhD Research Project Self-Funded PhD Students Only

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Tailoring Unspecific Peroxygenases (UPOs) for Applications in Synthetic Organic Chemistry

University of York Department of Chemistry

Background. The oxygenation of organic compounds presents an ongoing challenge to synthetic chemistry as conventional reagents present difficulties with toxicity, harsh conditions and poor selectivity. Read more

Supervisors: Prof G J Grogan, Dr W Unsworth, Dr J Cartwright

20 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Smart nutrient sensor networks using miniaturised optical and electrochemical detection

University of Plymouth Faculty of Science and Engineering

Applications are invited for a 3.5 years PhD studentship within the Environmental Intelligence doctoral training programme at the University of Plymouth. Read more

Supervisor: Dr S Ussher

26 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Molecular characterization of Marine Plastic Leachates and Associated Environmental Impacts

Atlantic Technological University Research

This PhD project is part of the Postgraduate Research Training Programme COASTAL CONNECTIVITY, which offers 12 PhD research scholarships to commence in 2024. Read more

Supervisors: Dr JF Frias , Dr S O'Reilly, Dr EG Gibney

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Establishing the effect of microplastic and nanoplastic exposure on inflammatory bowel disease

University of Plymouth Faculty of Health

Applications are invited for a three-year PhD studentship. The studentship will start on 01 October 2024. Project Description. Microplastics (<5 mm) are contaminating our food and mineral water. Read more

Supervisor: Dr N Clark

8 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Integration of AI to improve engagement from underserved groups with Digital Mental Health Pathways

Sheffield Hallam University Computing and Informatics

The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more

Supervisors: Dr MLDG Davila-Garcia, Prof H Soltani, Dr CR Roast

10 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Microfluidic technologies applied to respiratory diseases

Queen’s University Belfast School of Pharmacy

Subject area. 3D Printing, lab-on-a-chip, Drug Delivery, Pharmaceutical Technology. In Preclinical studies, a large number of molecules and biomolecules, in a very short time, have to be evaluated in terms of efficacy and toxicity. Read more

Supervisors: Prof D Lamprou, Prof M Tunney

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Microplastics and Nanoplastics as Emerging Risk Factors in Neurodevelopmental and Neurodegenerative Condition

University of Reading Department of Biomedical Sciences

Project Overview. Microplastics (MPs) and nanoplastics (NPs) are ubiquitous environmental pollutants raising concerns due to their potential adverse effects on human health. Read more

Supervisor: Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 60 toxicity PhD Projects, Programmes & Scholarships

toxicity PhD Projects, Programmes & Scholarships

We have 60 toxicity PhD Projects, Programmes & Scholarships

Understanding the emissions and toxicity from domestic burning in the UK

Determining the dietary accumulation and toxicity of nanoplastics and co-contaminants (zinc oxide nanomaterials) in fish

Uncovering the mechanisms of cryoprotectant toxicity and improving cryopreservation protocols

Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Leveraging metabolomics to reduce copper toxicity in dairy cattle

Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

Alpha-synuclein amyloid in Parkinson's disease: using Nanoinjection as a tool to study alpha-synuclein amyloid toxicity inside neurons

Analysing the role of statins in cardiovascular protection

Metal-based Antimicrobials: Tackling Resistance with Catalytic Redox Stressors

Fully funded studentship in Plastivore Plasticity: characterising metabolic flexibility in an emerging biotechnological system to manage plastic waste

Development of antibody-drug conjugates (ADCs) for oncology indications

Hepatic Models to personalise cancer chemotherapy

Shell-doped quantum dots as smart “on-off” catalysts for thermally sensitive organic transformations

Harnessing Breast Cancer Therapy: Innovative Formulation Strategies for Repurposing Medicines to Overcome Resistance

Modification of antibiotics to improve efficacy / safety

Enhancing PMMA Bone Cement Performance and Biocompatibility using Metal-Organic Frameworks

Degradable and resorbable polymeric cryoprotectants

Ultra-long coherence time diamond nanoparticles

Novel nanocomposites based on green resin chemistries reinforced with 2D nanofillers and natural fibres

Linking metabolism and metal resistance in pathogenic bacteria (SULLIVANM_U24AMSSCI)

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

(MRC DTP CASE) Designing Peptide hydrogels as vehicles for targeted and localised in-vivo therapeutics delivery

Delivery and misdelivery of outer membrane proteins to the BAM complex using cryoEM

Tailoring Unspecific Peroxygenases (UPOs) for Applications in Synthetic Organic Chemistry

Smart nutrient sensor networks using miniaturised optical and electrochemical detection

Molecular characterization of Marine Plastic Leachates and Associated Environmental Impacts

Establishing the effect of microplastic and nanoplastic exposure on inflammatory bowel disease

Integration of AI to improve engagement from underserved groups with Digital Mental Health Pathways

Microfluidic technologies applied to respiratory diseases

Microplastics and Nanoplastics as Emerging Risk Factors in Neurodevelopmental and Neurodegenerative Condition

We have 60 toxicity PhD Projects, Programmes & Scholarships

toxicity PhD Projects, Programmes & Scholarships

We have 60 toxicity PhD Projects, Programmes & Scholarships

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