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We have 16 Other PhD Projects, Programmes & Scholarships in Belfast

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Other PhD Projects, Programmes & Scholarships in Belfast

We have 16 Other PhD Projects, Programmes & Scholarships in Belfast

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Freeze-dried bacteriophage formulations against antibiotic-resistant bacteria

Queen’s University Belfast School of Pharmacy
Antimicrobial resistance (AMR) presents a significant global public health issue. Read more
 Supervisors: Dr T Skvortsov, Prof K Malcolm, Dr V Kett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Multipurpose gel formulations containing antiretroviral-loaded lactoferrin nanoparticles and antibiotics for combination HIV prevention and treatment of bacterial vaginosis

Queen’s University Belfast School of Pharmacy
This is an exemplar PhD project co-supervised by Dr. Sheiliza Carmali (School of Pharmacy) and Prof. Karl Malcolm (School or Pharmacy). Read more
 Supervisors: Dr S Carmali, Prof K Malcolm
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Dissecting the interface between Klebsiella pneumoniae and lung immune cells in vivo and the effect of new therapeutics.

Queen’s University Belfast School of Medicine, Dentistry & Biomedical Sciences
  Research Group: Wellcome-Wolfson Institute for Experimental Medicine
This collaborative PhD between GSK-Siena and the laboratory of Professor Jose Bengoechea at Queen’s University Belfast, is aimed at undertaking a multidisciplinary… Read more
 Supervisor: Prof J Bengoechea
 22 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Microfluidic Encapsulation of biologics into Nanomedicines

Queen’s University Belfast School of Pharmacy
Progress in drug design has led to the development of new peptides, proteins, and drug molecules. However, the limited ability to deliver selectively these molecules at well-defined dosing regimens and without invoking drug-resistance remains a significant challenge. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Designing and evaluating novel nanotherapeutics to enhance the effectiveness of radiotherapy in the treatment of solid cancers.

Queen’s University Belfast School of Pharmacy
One in two cancer patients will receive radiotherapy as part of their treatment. For patients with a localised cancer diagnosis effective radiotherapy represents the best chance of a curative outcome, however, is not without risk. Read more
 Supervisor: Dr J Coulter
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy
Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more
 Supervisor: Prof L Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Peptide-based nanoparticles for brain targeted gene delivery.

Queen’s University Belfast School of Pharmacy
Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more
 Supervisors: Dr E McErlean, Prof H McCarthy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genetic Engineering of Immune Effector Cells for CAR therapies using a Peptide Technology

Queen’s University Belfast School of Pharmacy
Chimeric antigen receptor (CAR)-T therapies have demonstrated remarkable treatment outcomes and several CAR-T therapies now approved for treatment of haematological malignancies. Read more
 Supervisors: Dr E McErlean, Prof H McCarthy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of the role of STAMBP as a therapeutic target in oesophageal cancer

Queen’s University Belfast School of Medicine, Dentistry & Biomedical Sciences
  Research Group: The Patrick G Johnston Centre for Cancer Research
Publicly available data from CRISPR knock out screens in hundreds of cell lines suggests a strong dependency on STAMBP in oesophageal cancer. Read more
 Supervisor: Prof R Kennedy
 1 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Targeting IRF4 in Multiple Myeloma using Molecular Glues

Queen’s University Belfast School of Medicine, Dentistry & Biomedical Sciences
  Research Group: The Patrick G Johnston Centre for Cancer Research
The IRF4 transcription factor represents a potential novel target in multiple myeloma but to date, it has not been druggable. This project aims to identify molecular glues that can lead to the specific degradation of IRF4. Read more
 Supervisor: Prof R Kennedy
 1 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Developing biodegradable long acting drug delivery systems for the treatment of chronic conditions

Queen’s University Belfast School of Pharmacy
Non-adherence to treatment costs the NHS more than £500M each year. Adherence is especially important when treating patients with chronic conditions that require lifetime pharmacological treatment, such as schizophrenia, Parkinson’s disease, HIV and Alzheimer’s disease. Read more
 Supervisors: Dr E Larraneta, Prof R Donnelly
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self-regulating, self-cleaning biomaterials

Queen’s University Belfast School of Pharmacy
A major problem associated with medical devices is infection. With infection rates of approaching 100% in some devices, ways to prevent formation of bacterial biofilm on medical device surfaces are urgently required. Read more
 Supervisors: Prof C McCoy, Dr M Wylie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self-Navigating Nanocarriers for Intracellular Protein Delivery

Queen’s University Belfast School of Pharmacy
Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more
 Supervisor: Dr W Al-Jamal
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self-Navigating Nanocarriers for Intracellular Protein Delivery

Queen’s University Belfast School of Pharmacy
Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more
 Supervisor: Dr W Al-Jamal
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Assessing the molecular mechanisms by which Cathepsin V promotes breast cancer growth and metastasis

Queen’s University Belfast School of Pharmacy
Targeted therapies such as tamoxifen, fulvestrant and anastrozole have exhibited significant clinical success since being introduced as treatments for Estrogen Receptor positive (ER+) breast cancer patients. Read more
 Supervisor: Dr R Burden
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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