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We have 45 Other PhD Projects, Programmes & Scholarships in Dundee

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Medicine

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Dundee  United Kingdom

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Other PhD Projects, Programmes & Scholarships in Dundee

We have 45 Other PhD Projects, Programmes & Scholarships in Dundee

Interdisciplinary investigation of a large effect of sulfasalazine on HbA1c

The anti-inflammatory drug sulfasalazine, which is used in rheumatoid arthritis and inflammatory bowel disease, was reported earlier to suppress HbA1c in a small cohort of patients [1]. Read more

Interdisciplinary investigation of the role of amino acids in immunometabolic responses to metformin in human cells

There is overwhelming evidence that inflammation contributes to the development of cardiovascular disease (CVD) but counterbalancing this is evidence from meta-analysis of randomised control trials that many existing anti-inflammatory drugs, such as COX2 inhibitors and anti-TNF drugs, tend if anything to exacerbate risk of CVD. Read more

Regulation of protein palmitoylation in the heart by persulphidation

Hydrogen sulphide (H2S) is known to have cardioprotective qualities. Persulphidation is a reversible post-translational modification (PTM) in which a persulphide group is formed by the reaction of H2S with the thiol groups of cysteine residues in proteins. Read more

Exploring innovative clinical teaching strategies and their implementation through the use of technology enhanced leaning: A case study of two medical schools, in Dundee and Iraq

Clinical teaching is one of the crucial components in the realm of medical education. It helps students to fill their knowledge gaps between theoretical foundation and practical training (Chapman & Clegg, 2007; Crane, 1991), linking theory to practice. Read more

The impact of social media networking on early career researchers’ wellbeing

Early career researchers’ wellbeing has been addressed by several studies, in terms of what factors could impact their wellbeing, what favoured elements could be present in their work environment to promote their academic progress. Read more

Exploring cardio-renal-metabolic interactions in patients with heart failure

Recent years have highlighted the connections and shared pathophysiology between heart failure, renal impairment, diabetes and obesity, particularly with the evidence of benefit in all of these areas with SGLT2 inhibitors and GLP1-receptor agonists. Read more

Investigation of short-term effects of colchicine on blood proteins using proteomics

The anti-inflammatory medication colchicine has been shown to significantly improve cardiovascular outcomes post heart attack and in chronic heart disease patient groups, suggesting it may be a suitable candidate for repurposing in cardiovascular diseases. Read more

Lessening Health Inequalities in Type 2 Diabetes Through Innovative Drug Repurposing

Most older type 2 diabetes (T2D) drugs were developed through pre-clinical studies and then trials that model T2D as it is experienced by older white people (1). Read more

Learning and Memory in the response to recurrent hypoglycaemia in diabetes

Recurrent hypoglycaemia has both acute and chronic consequences and is greatly feared by people with type 1 diabetes. Work from our laboratory over the last few years has revealed that the brain adaptation to recurrent hypoglycaemia in type 1 diabetes represents a specialised form of memory called habituation. Read more

The effect of early-life stress on cardiac function in later life

Stressful experiences in early childhood can increase the risk of cardiovascular disease (CVD) in later life. How early-life stress (ELS) influences susceptibility to CVD onset remains largely unknown. Read more

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