Other (cystic fibrosis) PhD Projects, Programmes & Scholarships

We have 6 Other (cystic fibrosis) PhD Projects, Programmes & Scholarships

Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

University of Leeds Faculty of Medicine and Health

Cystic fibrosis (CF) is associated with an accentuated inflammatory response to bacterial lipopolysaccharides (LPS), increased resting energy expenditure and a higher than expected prevalence of gastrointestinal and other malignancies. Read more

Supervisors: Prof D Peckham, Prof D Jayne, Dr S Savic, Miss LR Caley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy

Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

University of Leeds Faculty of Medicine and Health

Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more

Supervisors: Prof L Houghton, Dr D Peckham

Year round applications PhD Research Project Self-Funded PhD Students Only

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Health and education outcomes of children with Sickle Cell Disease in England

Great Ormond Street Hospital for Children NHS Trust GOSH BRC Applied Child Health Informatics Theme (Non-Clinical) PhD Studentships

SCD is a serious, life-long condition that can cause anaemia, increased infection risk, and pain.1 Around 300 babies are born with SCD annually in the UK. Read more

Supervisors: Dr R Knowles, Prof P Hardelid

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Nanoparticle delivery of antibiotics for treatment of pulmonary infection

Queen’s University Belfast School of Pharmacy

Antimicrobial resistance (AMR) poses a major global risk to human health by causing death, disability, longer hospitalisations, and increased healthcare costs. Read more

Supervisors: Dr V Kett, Prof M Tunney

Year round applications PhD Research Project Self-Funded PhD Students Only

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Regulation of virulence and biofilm formation by quorum sensing and the "stress alarmone" ppGpp in gram-negative pathogenic bacteria.

University of Cambridge Department of Biochemistry

We are investigating the complex interplay between cell-cell signalling (quorum sensing), microbial lifestyle (i.e., free-living planktonic cultures vs sessile biofilm communities), growth phase and virulence in gram-negative bacteria. Read more

Supervisor: Dr M Welch

Year round applications PhD Research Project Awaiting Funding Decision/Possible External Funding

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We have 6 Other (cystic fibrosis) PhD Projects, Programmes & Scholarships

Other (cystic fibrosis) PhD Projects, Programmes & Scholarships

We have 6 Other (cystic fibrosis) PhD Projects, Programmes & Scholarships

Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

Selective targeting of furin for the treatment of fibrotic lung disease.

Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

Health and education outcomes of children with Sickle Cell Disease in England

Nanoparticle delivery of antibiotics for treatment of pulmonary infection

Regulation of virulence and biofilm formation by quorum sensing and the "stress alarmone" ppGpp in gram-negative pathogenic bacteria.

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