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We have 20 Other (regulation) PhD Projects, Programmes & Scholarships

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Other (regulation) PhD Projects, Programmes & Scholarships

We have 20 Other (regulation) PhD Projects, Programmes & Scholarships

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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School
Genome wide association studies (GWAS) have discovered many genetic associations for traits and diseases. However, most GWAS signals reside in non-coding regions (outside genes), and it is likely that GWAS variants confer their effects through modulating regulatory mechanism. Read more
 Supervisor: Dr J Min
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School
Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more
 Supervisors: Dr J Min, Dr E Hannon, Prof J MIll, Dr GL Leyden
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Characterization of cyclin-dependent kinase 12 (CDK12) substrates and their roles in regulation of transcription and tumorigenesis

Masaryk University Faculty of Medicine
Doctoral study program. Life Sciences. Research area. RNA/nucleic acids research in health, cancer biology. Cdk12 is transcriptional cyclin-dependent kinase (Cdk) found mutated in various cancers. Read more
 Supervisor: Dr D Blažek
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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The regulation of platelet function - towards new strategies to prevent thrombosis

University of Reading Department of Biomedical Sciences
Project Overview. Platelets perform a pivotal role in the regulation of haemostasis, a physiological response to injury that prevents excessive bleeding. Read more
 Supervisor: Prof J M Gibbins
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Regulation of protein palmitoylation in the heart by persulphidation

University of Dundee School of Medicine
Hydrogen sulphide (H2S) is known to have cardioprotective qualities. Persulphidation is a reversible post-translational modification (PTM) in which a persulphide group is formed by the reaction of H2S with the thiol groups of cysteine residues in proteins. Read more
 Supervisors: Dr N Fraser, Dr C Murdoch
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Regulation of virulence and biofilm formation by quorum sensing and the "stress alarmone" ppGpp in gram-negative pathogenic bacteria.

University of Cambridge Department of Biochemistry
We are investigating the complex interplay between cell-cell signalling (quorum sensing), microbial lifestyle (i.e., free-living planktonic cultures vs sessile biofilm communities), growth phase and virulence in gram-negative bacteria. Read more
 Supervisor: Dr M Welch
 Year round applications  PhD Research Project  Awaiting Funding Decision/Possible External Funding
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MSc By Research: Does Rif1 affect meiotic recombination and chromosome segregation in Schizosaccharomyces pombe?

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Dr A Lorenz, Dr H Murakami
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cross-talks of immune checkpoint pathways determine the abilities of human malignant tumours to suppress cytotoxic attacks and escape immune surveillance

University of Greenwich School of Pharmacy (Medway Campus)
Overview. Immune checkpoint pathways determine the abilities of human malignant tumours to escape cytotoxic immune attack and thus progress the disease. Read more
 Supervisor: Dr V Sumbayev
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cross-talks of immune checkpoint pathways determine the abilities of human malignant tumours to suppress cytotoxic attacks and escape immune surveillance

University of Kent Medway School of Pharmacy
Overview. Immune checkpoint pathways determine the abilities of human malignant tumours to escape cytotoxic immune attack and thus progress the disease. Read more
 Supervisor: Dr V Sumbayev
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology
More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more
 Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular Mechanisms of Resolution of Inflammation

University of Birmingham Institute of Inflammation and Ageing
We are seeking talented, motivated students to join the research group led by Professor Andy Clark (https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/clark-andy.aspx), a member of the University of Birmingham’s Rheumatology Research Group (https://www.birmingham.ac.uk/research/inflammation-ageing/research/rheumatology-research-group/index.aspx). Read more
 Supervisor: Prof A Clark
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Sheffield Hallam University - Psychology Demonstratorships: Understanding interpersonal aspects of perimenopause

Sheffield Hallam University Faculty of Social Sciences and Humanities
Applications are invited for Psychology Demonstratorships in the department of Psychology, Sociology, and Politics, commencing October 2024. Read more
 Supervisor: Dr HH Humphreys
 24 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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The role of extracellular vesicles and intercellular signalling in inherited kidney cancer

Cardiff University Cardiff School of Medicine
This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£60,000 total). Read more
 Supervisor: Dr E Dunlop
 31 May 2024  PhD Research Project  Self-Funded PhD Students Only
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Relationship between IFNγ-dependent tumour escape and immunotherapy

University of Oxford Kennedy Institute of Rheumatology
Tumours actively escape the immune system by inducing an immunosuppressive state whereby intra-tumoural CD8 T-cells are “exhausted”, lacking effector functions. Read more
 Supervisors: Dr A Gérard, Dr C Leung
 3 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Novel regulatory pathways leading to Neutrophil Activation

Queen’s University Belfast School of Medicine, Dentistry & Biomedical Sciences
In chronic lung diseases such as Cystic Fibrosis lung disease or Chronic Obstructive Pulmonary Disease, the lung is susceptible to destruction of lung tissue by human cells that normally participate in removing bacteria from the lung. Read more
 Supervisors: Prof C Taggart, Dr R Williams
 17 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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