Toxicology (drug development) PhD Projects, Programmes & Scholarships

We have 14 Toxicology (drug development) PhD Projects, Programmes & Scholarships

Crystal engineering new, more effective medicines.

BACKGROUND. Neglected Tropical Diseases (NTDs) – a diverse group of infectious diseases – continue to thrive across low- income populations. Read more

Supervisor: Dr O Kavanagh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more

Supervisors: Dr S Shnyder, Dr S Kantamneni

Year round applications PhD Research Project Self-Funded PhD Students Only

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Drug metabolism - prediction, detection, and isolation

University of Birmingham School of Pharmacy

Electrosynthesis (ES) is a green methodology for preparing and interpreting drug metabolites linked to toxicology. ES describes the synthesis of chemical compounds in an electrochemical cell. Read more

Supervisor: Dr M Jones

Year round applications PhD Research Project Self-Funded PhD Students Only

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Engineering functional human tissue: Development of a 3D cerebral microvascular model with blood brain barrier function.

University of Strathclyde Department of Biomedical Engineering

There is mounting research interest in tissue engineered models of human blood brain barrier (BBB) due to the prevalence of central nervous system (CNS) disease in modern societies. Read more

Supervisors: Dr J Wu, Prof W Shu

15 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Crystal engineering new, more effective medicines.

Newcastle University Faculty of Medical Sciences Graduate School

RESEARCH PROJECT. To uncover pharmaceutical problems, our team collaborates with a wide range of disciplines, including pharmacists, pharmaceutical scientists, chemists and engineers at internationally renowned pharmacy departments and at multinational pharmaceutical companies. Read more

Supervisor: Dr O Kavanagh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Supervisors: Prof R Falconer, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of a personalized therapy for pulmonary arterial hypertension (PAH)

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Supervisor: Dr T Nasim

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Polysialyltransferases as a target in metastatic cancer

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more

Supervisors: Prof R Falconer, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Supervisor: Dr T You

1 August 2024 PhD Research Project Self-Funded PhD Students Only

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Testing the translational power of zebrafish for studying human heart failure. Ref: 5101

University of Exeter BBSRC South West Doctoral Training Partnership

Supervisors. Dr Matthew Winter, University of Exeter. Dr Yosuke Ono, University of Exeter. Location. Biosciences, Streatham Campus, Exeter. Read more

Supervisors: Dr M Winter, Dr YO Ono

22 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating the impact of galectin-ligand interaction on cancer cell resistance to chemotherapeutic treatment

University of Liverpool Institute of Life Course and Medical Sciences

Galectins are multifunctional carbohydrate-binding proteins that are expressed by many types of human cells. Changes of galectin expression commonly occur in cancer (e.g. Read more

Supervisor: Prof LG Yu

Year round applications PhD Research Project Self-Funded PhD Students Only

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Hepatic Models to personalise cancer chemotherapy

University of Liverpool Department of Pharmacology and Therapeutics

The most commonly used chemotherapy regimens for colorectal cancer with liver metastases are oxaliplatin combined with 5-FU and leucovorin, i.e. Read more

Supervisors: Prof C Goldring, Dr A Chadwick, Prof IC Copple, Dr S Pushpakom

Year round applications PhD Research Project Self-Funded PhD Students Only

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Network-based predictive modelling of cardiovascular disease risk

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The risk of cardiovascular disease (CVD) is orchestrated by multiple factors. QRISK models (currently QRISK3) have been used in the UK to estimate CVD risk within the next 10 years for individuals without CVD. Read more

Supervisor: Dr T You

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 14 Toxicology (drug development) PhD Projects, Programmes & Scholarships

Toxicology (drug development) PhD Projects, Programmes & Scholarships

We have 14 Toxicology (drug development) PhD Projects, Programmes & Scholarships

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