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We have 19 The University of Manchester Organic Chemistry PhD Projects, Programmes & Scholarships

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Chemistry

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The University of Manchester

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The University of Manchester Organic Chemistry PhD Projects, Programmes & Scholarships

We have 19 The University of Manchester Organic Chemistry PhD Projects, Programmes & Scholarships

Developing novel light-induced in-situ Electron Paramagnetic Resonance (EPR) methods

Light-induced in-situ Electron Paramagnetic Resonance (EPR) studies are a growing field in both continuous wave and pulsed EPR. It can be used to monitor photoactivated chemical and biochemical reactions involving radical reagents, projects or intermediates. Read more

Development of new retrosynthetic disconnections through radical-nucleophilic substitution

Background. Nucleophilic substitution is arguably the most important class of reaction in organic synthesis. Indeed, these reactions are used every day to synthesise new pharmaceuticals, agrochemicals, polymers and natural products. Read more
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Mechanochemistry with mechanical bonds

Any force developed at the macroscopic scale can induce dramatic changes at the molecular scale, even breaking covalent bonds.[1] Indeed, mechanical force is a formidable source of energy that, with its ability to distort, bend and stretch chemical bonds, is unique in its ability to promote reaction pathways that are otherwise inaccessible to traditional methods of activation. Read more

EPSRC - Light-coupled NMR to design novel photo-driven chemistry and materials

Over the last decade, visible light-driven chemistry has come to the forefront of modern organic synthesis, chemical biology, and materials science, providing a powerful platform through which to rapidly construct new and complex molecules. Read more

Cooperative catalysis using iron-based Organometallic frustrated Lewis pairs

Frustrated Lewis pairs (FLPs) has led to major advances in the field of small molecule activation and catalysis, being considered as one of the most exciting modern-day developments in main group chemistry. Read more

Photoredox molecular editing for enhanced drug discovery

Molecular editing platforms, the process by which single atoms can be inserted or deleted selectively in or around a molecule’s skeleton, are transformative to synthetic chemists across industry and academia for the streamlined development of new drugs. Read more

Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

Plastics are a broad range of solid polymeric materials that have found widespread application globally. However, there has been a steady accumulation of discarded plastics and there is now growing awareness that they present a significant hazard to the natural environment and human health. Read more

A new twist on catalysis: folded oligomers with organometallic termini

A key feature of biological systems is the storage and transmission of information across multi-nanometre distances, which maintains the complex chemical networks and functions within cells. Read more

Degradable and resorbable polymeric cryoprotectants

Extremophiles have evolved to survive in the world’s coldest environments, through the production of specialised macromolecules, such as antifreeze proteins and ‘ice nucleating proteins. Read more

Taking Light Induced Electron Paramagnetic Resonance In Cell for Biological Structural Determination

Studying the structure of proteins and other biological systems is an important step in understanding their function. Most structural studies are conducted in environments that are far away from native conditions, such as those found inside a cell. Read more

Ion irradiation of advanced nuclear fuels

Nuclear fission power currently accounts for 20% of UK energy production, making it a key low-carbon energy source for reducing greenhouse gases and meeting the governments New-Zero target by 2050. Read more
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