Pharmaceutical Chemistry PhD Research Projects PhD Projects, Programmes & Scholarships in Leeds

We have 14 Pharmaceutical Chemistry PhD Research Projects PhD Projects, Programmes & Scholarships in Leeds

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Supervisor: Dr Muhammad Wahajuddin

Year round applications PhD Research Project Self-Funded PhD Students Only

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How to regulate plasticity in the brain

University of Leeds Faculty of Biological Sciences

The Kwok Lab at the School of Biomedical Science invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Dr J. Kwok

Year round applications PhD Research Project Self-Funded PhD Students Only

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Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

University of Leeds Faculty of Biological Sciences

Research Group: Astbury Centre for Structural Molecular Biology

Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more

Supervisors: Prof A O'Neill, Dr M McPhillie, Prof C Fishwick

Year round applications PhD Research Project Self-Funded PhD Students Only

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Particle properties by design

University of Leeds Faculty of Engineering and Physical Sciences

Research Group: School of Chemical and Process Engineering

This interdisciplinary project presents an exciting opportunity for an ambitious scientist or engineer to work across the boundaries of chemistry, physics and engineering, with opportunities to develop a broad portfolio of skills. Read more

Supervisor: Dr A R Pallipurath

17 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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EPSRC Doctoral Training Partnership 2024/25: Chemistry

University of Leeds Faculty of Engineering and Physical Sciences

Research Group: School of Chemistry

Becoming an innovator in the School of Chemistry at the University of Leeds!. For 2024/25 entry, we are offering you the opportunity to join our thriving community of leading researchers within the School of Chemistry. Read more

Supervisor: Ms L Moyles

29 April 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more

Supervisors: Dr T Nasim, Dr M Najafzadeh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identifying cognitive and biochemical changes underlying lifestyle risk factors for dementia

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Dementia describes a group of age-associated conditions of which cognitive decline is a major feature. Alzheimer’s disease (AD) is the most common cause of dementia and is characterised by the onset of a gradual cognitive decline. Read more

Supervisors: Dr S McLean, Dr R Williamson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Directed Co-Crystallisation of Pharmaceuticals: developing a predictive method for co-crystallisation

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

In this project, we propose to use a combination of computational and experimental techniques to develop a predictive method for co-crystallisation. Read more

Supervisor: Dr C Seaton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Supervisors: Prof R Falconer, Prof P Loadman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Supervisors: Prof R Falconer, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Biological rhythms and the dopamine system in cognitive dysfunction

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more

Supervisors: Dr S McLean, Dr G Helfer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Therapeutic resolution of BMPR2-mediated signalling defects in pulmonary arterial hypertension (PAH)

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Pulmonary arterial hypertension (PAH) is an incurable and devastating disease and death occurs within 2.5 years of diagnosis. Read more

Supervisors: Dr T Nasim, Dr R Gopalan

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 14 Pharmaceutical Chemistry PhD Research Projects PhD Projects, Programmes & Scholarships in Leeds

Pharmaceutical Chemistry PhD Research Projects PhD Projects, Programmes & Scholarships in Leeds

We have 14 Pharmaceutical Chemistry PhD Research Projects PhD Projects, Programmes & Scholarships in Leeds

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