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We have 35 Pharmaceutical Chemistry (biology) PhD Projects, Programmes & Scholarships

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Pharmaceutical Chemistry (biology) PhD Projects, Programmes & Scholarships

We have 35 Pharmaceutical Chemistry (biology) PhD Projects, Programmes & Scholarships

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Does one size fit all for antimicrobial delivery via nanoparticles

Queen’s University Belfast School of Pharmacy
Antimicrobial resistant bacteria are a growing problem and new ways are needed to target bacterial infections more efficiently. One way in which bacteria can avoid therapeutics is via intracellular infection, where they hide within our own cells. Read more
 Supervisors: Dr J Burrows, Prof B Gilmore
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Targeting the mechanism of small GTPase splice variant RAC1B using ligand design

The University of Manchester Faculty of Biology, Medicine and Health
RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more
 Supervisors: Dr RB Bryce, Dr S Butterworth, Dr T Jowitt, Dr A Ucar
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Fluorinated tools for chemical biology

University of Edinburgh School of Chemistry
A PhD studentship is available in the group of Dr Chris Coxon, School of Chemistry, University of Edinburgh, https://www.chem.ed.ac.uk/staff/academic-staff/dr-christopher-r-coxon. Read more
 Supervisor: Dr C Coxon
 31 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry
Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more
 Supervisors: Prof E Takano, Prof H Oguri
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Studying of cancer biology with doped magnetic nanomaterials to unravelling their thermal therapeutic potentials

University College London Department of Physics and Astronomy
Cancer has a major impact on society, this is reflected by the large number of newly diagnosed cases (375,400 annually for the years 2015-2018 in the UK, i.e. Read more
 Supervisor: Prof N T K Thanh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Disrupting Oral Biofilm Formation & Maturation: Covalently Inhibiting Glucan Sucrases from Streptococci

University of Southampton Faculty of Engineering and Physical Sciences
Supervisory Team: Dr Seung Lee (School of Chemistry), Prof. Jeremy Webb (School of Biological Sciences and National Biofilms Innovation Centre), Prof. Read more
 Supervisor: Dr SS Lee
 31 August 2024  PhD Research Project  Competition Funded PhD Project (European/UK Students Only)
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MSc by Research: Glueing proteins together with small molecules

University of Dundee School of Life Sciences
Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more
 Supervisor: Prof A Ciulli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

The University of Manchester Faculty of Biology, Medicine and Health
Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more
 Supervisors: Dr A Politis, Dr CP Pliotas
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

University of Leeds Faculty of Biological Sciences
  Research Group: Astbury Centre for Structural Molecular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more
 Supervisors: Prof A O'Neill, Dr M McPhillie, Prof C Fishwick
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology
What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more
 Supervisors: Dr JF Fox, Dr JH Hodgkinson
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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High-throughput characterization and engineering of nucleotide synthases for production of nucleoside analogues

The University of Manchester Department of Chemistry
Nucleotides are the building blocks of life, modulating diverse processes from protein production to cell signalling. It is therefore unsurprising that synthetic nucleoside analogues have been developed as therapeutics for the treatment of a wide range of diseases including cancers and viral infections. Read more
 Supervisors: Dr S Lovelock, Dr C Markin
 31 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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From bench to pre-clinical evaluation: a novel nucleic acid vaccine targeting tumour-associated antigens

Royal College of Surgeons in Ireland Molecular and Cellular Therapeutics
Cancer and the long-term toxicities sustained from treatment remain a public health issue for adult and paediatric patients. The spread of tumour cells is believed to account for up to 90% of cancer-related morbidities. Read more
 Supervisor: Dr O Piskareva
 1 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Breaking the resistance: alternative approaches to antibiotics discovery

Queen’s University Belfast School of Pharmacy
The World Health Organisation (WHO) identifies antimicrobial resistance (AMR) as one of the top 10 global threats to human health (http://www.who.int/). Read more
 Supervisor: Prof G Wagner
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Breaking the resistance: alternative approaches to antibiotics discovery

Queen’s University Belfast School of Pharmacy
The World Health Organisation (WHO) identifies antimicrobial resistance (AMR) as one of the top 10 global threats to human health (http://www.who.int/). Read more
 Supervisor: Prof G Wagner
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Harnessing Breast Cancer Therapy: Innovative Formulation Strategies for Repurposing Medicines to Overcome Resistance

Kingston University Faculty of Health, Science, Social Care and Education
Background. Research in the Kadri group focuses on developing innovative chemical approaches for the discovery of novel therapeutics to address unmet global health needs. Read more
 Supervisor: Dr H Kadri
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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