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We have 13 Pharmaceutical Chemistry (financial) PhD Projects, Programmes & Scholarships

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Pharmaceutical Chemistry (financial) PhD Projects, Programmes & Scholarships

We have 13 Pharmaceutical Chemistry (financial) PhD Projects, Programmes & Scholarships

From bench to pre-clinical evaluation: a novel nucleic acid vaccine targeting tumour-associated antigens

Cancer and the long-term toxicities sustained from treatment remain a public health issue for adult and paediatric patients. The spread of tumour cells is believed to account for up to 90% of cancer-related morbidities. Read more

Mechanistic design of effective pharmaceutical cocrystal formulations

It is estimated that more than 70 percent of the compounds in the pharmaceutical pipeline can be poorly water-soluble. Since solid drug forms must dissolve before absorption can occur, strategies to improve drug solubility and dissolution are a continuous need. Read more

Shared decision making and psychosis – whose voice counts in the conversations about stopping or reducing antipsychotic medication

Prescribing antipsychotics has increased steadily in England over the last decade. For serious mental health conditions like schizophrenia, they are prescribed with the view of keeping the patient on them indefinitely. Read more

Crystal engineering new, more effective medicines.

RESEARCH PROJECT. To uncover pharmaceutical problems, our team collaborates with a wide range of disciplines, including pharmacists, pharmaceutical scientists, chemists and engineers at internationally renowned pharmacy departments and at multinational pharmaceutical companies. Read more

The development of new antiviral agents targeting HIV-1

Even before the current global COVID-19 pandemic, the threat posed to human health by viruses was extensive and although significant progress in targeting some viruses (e.g., HIV-1 and hepatitis C) has been made, challenges remain. Read more

Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

  Research Group: Institute of Cancer Therapeutics
Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

  Research Group: Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Directed Co-Crystallisation of Pharmaceuticals: developing a predictive method for co-crystallisation

  Research Group: Chemistry and Biosciences
In this project, we propose to use a combination of computational and experimental techniques to develop a predictive method for co-crystallisation. Read more

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
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