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We have 18 Pharmaceutical Chemistry (medicinal) PhD Projects, Programmes & Scholarships

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Pharmaceutical Chemistry (medicinal) PhD Projects, Programmes & Scholarships

We have 18 Pharmaceutical Chemistry (medicinal) PhD Projects, Programmes & Scholarships

Design and synthesis of chemical tools to interrogate cannabinoid receptors - synthetic, medicinal chemistry

Research project. We are seeking a highly motivated PhD candidate to join an interdisciplinary team at the University of Otago, to undertake research developing chemical probes for the cannabinoid receptor, a type of G protein-coupled receptor (GPCR). Read more

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

  Research Group: Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Design and study of modified peptide foldamers

These projects are open to students worldwide, but have no funding attached. Therefore, the successful applicant will be expected to fund tuition fees at the relevant level (home or international) and any applicable additional research costs. Read more

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

How to regulate plasticity in the brain

The Kwok Lab at the School of Biomedical Science invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Small molecule cancer drug discovery targeting resistant disease.

Despite continuous advances in targeted cancer therapy in recent years, there remains a major challenge to combat drug resistance and poor levels of efficacy in areas of unmet medical need, such as advanced colorectal and breast cancer. Read more

Cardiotoxicity of Anticancer Drugs

Faculty of Pharmacy, Charles University, Department of Biochemical Sciences. The project fits into the field of cardio-oncology, which deals with the detection, prevention and treatment of cardiovascular diseases that occur as a side effect of chemotherapy and radiotherapy. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

MSc by Research: Glueing proteins together with small molecules

Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more

Mining the Hippo signalling pathway for novel anti-cancer therapeutics

Candidates are invited to join the Kadri Lab, where our research focuses on developing innovative chemical approaches for discovering novel therapeutics to address unmet global health needs. Read more

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