The University of Manchester Synthetic Chemistry PhD Projects, Programmes & Scholarships

We have 15 The University of Manchester Synthetic Chemistry PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Targeting the mechanism of small GTPase splice variant RAC1B using ligand design

The University of Manchester Faculty of Biology, Medicine and Health

RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more

Supervisors: Dr RB Bryce, Dr S Butterworth, Dr T Jowitt, Dr A Ucar

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of new retrosynthetic disconnections through radical-nucleophilic substitution

The University of Manchester Department of Chemistry

Background. Nucleophilic substitution is arguably the most important class of reaction in organic synthesis. Indeed, these reactions are used every day to synthesise new pharmaceuticals, agrochemicals, polymers and natural products. Read more

Supervisor: Dr M James

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Mechanochemistry with mechanical bonds

The University of Manchester Department of Chemistry

Any force developed at the macroscopic scale can induce dramatic changes at the molecular scale, even breaking covalent bonds.[1] Indeed, mechanical force is a formidable source of energy that, with its ability to distort, bend and stretch chemical bonds, is unique in its ability to promote reaction pathways that are otherwise inaccessible to traditional methods of activation. Read more

Supervisor: Prof G De Bo

26 April 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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High Entropy 2D Materials for Efficient Water Splitting - Postgraduate Research Teaching Associate (PGRTA) Scholarship

The University of Manchester Department of Materials

We invite applications for a fully-funded Ph.D. position to conduct cutting-edge research in the field of high entropy 2D materials for water splitting, building upon our recent publications in the field (Chemistry of Materials 35 (19), 7904-7914; Advanced Science, 2204488). Read more

Supervisor: Dr D Lewis

3 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Development of advanced scintillation materials for next generation radiation dosimetry and health monitoring

The University of Manchester Department of Chemistry

Ionising radiation is a part and parcel of nuclear energy production, medical radiotherapy and radiography, space exploration and security screening. Read more

Supervisors: Dr A Romanov, Dr A Baidak

30 June 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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EPSRC - Light-coupled NMR to design novel photo-driven chemistry and materials

The University of Manchester Department of Chemistry

Over the last decade, visible light-driven chemistry has come to the forefront of modern organic synthesis, chemical biology, and materials science, providing a powerful platform through which to rapidly construct new and complex molecules. Read more

Supervisors: Dr A Golovanov, Dr L Natrajan, Dr A Trowbridge

1 October 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Cooperative catalysis using iron-based Organometallic frustrated Lewis pairs

The University of Manchester Department of Chemistry

Frustrated Lewis pairs (FLPs) has led to major advances in the field of small molecule activation and catalysis, being considered as one of the most exciting modern-day developments in main group chemistry. Read more

Supervisor: Dr D Willcox

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Targeting glycans on the outside of cells, as new therapeutics

The University of Manchester Department of Chemistry

Most drugs have intracellular targets (proteins etc). This creates a barrier to how to target a cell, and then get the drug inside the cell. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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EPSRC - Synthesis of Supramolecules to Perform Light-Switchable Quantum Gates

The University of Manchester Department of Chemistry

An EPSRC DTG-sponsored PhD studentship is available to undertake research in making supramolecules to perform two-qubit gates by EPR spectroscopy in a collaborative project between three research groups at Manchester Chemistry. Read more

Supervisors: Dr A Bowen, Prof R Winpenny, Prof E McInnes

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Photoredox molecular editing for enhanced drug discovery

The University of Manchester Department of Chemistry

Molecular editing platforms, the process by which single atoms can be inserted or deleted selectively in or around a molecule’s skeleton, are transformative to synthetic chemists across industry and academia for the streamlined development of new drugs. Read more

Supervisor: Dr A Trowbridge

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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A new twist on catalysis: folded oligomers with organometallic termini

The University of Manchester Department of Chemistry

A key feature of biological systems is the storage and transmission of information across multi-nanometre distances, which maintains the complex chemical networks and functions within cells. Read more

Supervisor: Dr S Webb

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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High-throughput biomaterials discovery

The University of Manchester Department of Chemistry

Polymer biomaterials have revolutionised a range of areas from drug delivery, to antimicrobials, to cellular cryopreservation. There are 1000’s of possible monomer combinations, molecular weights and architectures to be explored, and even small differences can dramatically change their properties. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Degradable and resorbable polymeric cryoprotectants

The University of Manchester Department of Chemistry

Extremophiles have evolved to survive in the world’s coldest environments, through the production of specialised macromolecules, such as antifreeze proteins and ‘ice nucleating proteins. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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We have 15 The University of Manchester Synthetic Chemistry PhD Projects, Programmes & Scholarships

The University of Manchester Synthetic Chemistry PhD Projects, Programmes & Scholarships

We have 15 The University of Manchester Synthetic Chemistry PhD Projects, Programmes & Scholarships

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