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We have 20 Synthetic Chemistry (proteins) PhD Projects, Programmes & Scholarships

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Synthetic Chemistry (proteins) PhD Projects, Programmes & Scholarships

We have 20 Synthetic Chemistry (proteins) PhD Projects, Programmes & Scholarships

Chemical modification of proteins via metal-mediated processes

Chemically modified proteins can be used to understand, treat, and diagnose disease. However, relatively few chemical reactions can be used to modify proteins, severely limiting the diversity and applications of new technologies. Read more

Developing novel targeted therapeutic approaches through induced-proximity of proteins

Protein post-translational code is at the heart of protein function and signal transduction in cells. Enzymes catalyse the addition or removal of post-translational modifications (PTM), such as phosphorylation, methylation, acetylation, and ubiquitylation, on proteins. Read more

Wearable Sample Collection for Biosensing

Measurement of low abundance proteins is key for enabling early detection of diseases [1]. A widely used method for the measurement of low abundance proteins is enzyme-linked immunosorbent assay (ELISA) [2]. Read more

Degradable and resorbable polymeric cryoprotectants

Extremophiles have evolved to survive in the world’s coldest environments, through the production of specialised macromolecules, such as antifreeze proteins and ‘ice nucleating proteins. Read more

Novel strategies for the diagnosis and treatment of snakebites

Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more

PhD studentship in Organic/Supramolecular Chemistry

A fully funded PhD position (tuition fees and stipend) is available in the group of Dr James Cooper (https://www.cooperchemistry.com/) at the University of Reading. Read more

Synthesis of Novel Organic Probes for the Study of Lipid-Lipid Interactions

Lipids are diverse and principal components of the cell and are involved in a vast array of processes ranging from their well-known structural importance in cell membranes, through to energy storage and participation in signalling pathways. Read more

An Interdisciplinary Approach to Developing of Macrocyclic Inhibitors of the MAPK Pathway

Supervisory Team: Prof Ali Tavassoli . Project Description. We are seekign an outstanding chemistry student with an interest in chemical biology to work on a project to develop cyclic peptide inhibitors of a protein-protein interaction that is heavily implicated in the development and growth of tumours. . Read more

Glycan sensing technology for early and accurate cancer diagnosis

The Mendes group (https://www.birmingham.ac.uk/research/healthcare-technologies/research/nanoengineering-surface-chemistry/index.aspx) in the School of Chemical Engineering, University of Birmingham welcomes applications from prospective PhD students to conduct work in the area of glycan sensing technology for cancer diagnosis. Read more

Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

Redox properties of metal-containing active sites are critically important to many biocatalytic processes. one third of all proteins contain a redox-active metal, and ca 22% of submissions to the Protein Data Bank contain a transition metal. Read more

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