Immunology PhD Research Projects PhD Projects, Programmes & Scholarships in Manchester

We have 20 Immunology PhD Research Projects PhD Projects, Programmes & Scholarships in Manchester

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Mapping CD4+ T cell fate decisions and functional coordination within tissues during infection

The University of Manchester Faculty of Biology, Medicine and Health

CD4+ T cells are essential components of the immune system, orchestrating protection against infection. Read more

Supervisors: Dr K Couper, Prof DD Dyer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Determining how immune responses are regulated in the lung and gut by the local environment

The University of Manchester Faculty of Biology, Medicine and Health

The immune system must respond quickly to infection but must also be tightly regulated so it ignores harmless substances and our own tissues. Read more

Supervisors: Prof M Travis, Prof R K Grencis, Prof D Thornton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding how to target the T cell compartment within related brain tumours

The University of Manchester Faculty of Biology, Medicine and Health

T cell-based immunotherapy has revolutionised the treatment of many different types of cancer. However, to date, these treatments have not been successful or widely used for the treatment of brain tumours. Read more

Supervisors: Dr K Couper, Prof D Brough, Dr OP Pathmanaban

Year round applications PhD Research Project Self-Funded PhD Students Only

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Diagnostics for FMF patients and carrier survival in pandemics

The University of Manchester Faculty of Biology, Medicine and Health

Background. Familial Mediterranean Fever (FMF) is a rare inherited genetic disease where patients acquire a mutation on the pyrin gene leading to excessive inflammasome activation and excessive inflammation. Read more

Supervisors: Dr P Arkwright, Dr G Lopez-Castejon, Dr J Cavet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identification and characterization of disease-specific subsets of antigen-presenting cells (APC) in inflammatory arthritis

The University of Manchester Faculty of Biology, Medicine and Health

Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies. Read more

Supervisors: Dr S Viatte, Prof A Barton, Mr P Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Defining the protective effects of a commensal bacterial strain in skin barrier function and protection from disease

The University of Manchester Faculty of Biology, Medicine and Health

Maintaining a healthy skin barrier is vital for our health. In response to skin wounding, we have a well-orchestrated immune response that heals the breach. Read more

Supervisors: Prof S Cruickshank, Prof A McBain, Dr R Unwin

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

The University of Manchester Faculty of Biology, Medicine and Health

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Supervisors: Prof D Brough, Dr K Couper

13 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Repurposing Treg cells for TIL therapy

The University of Manchester Faculty of Biology, Medicine and Health

Tumour-infiltrating lymphocytes (TIL) therapy is an experimental therapy which uses ex-vivo expanded TIL as a source of living drug to treat cancer. Read more

Supervisors: Dr A Hurlstone, Prof M Travis, Prof R Edmondson, Prof F Thistlethwaite

19 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating the genetic basis of immunological overlap between inflammatory diseases

The University of Manchester Faculty of Biology, Medicine and Health

Genetic studies have identified numerous variants within the human genome associated with susceptibility to common complex inflammatory diseases, such as rheumatoid arthritis (RA) and ulcerative colitis (UC). Read more

Supervisors: Mr P Martin, Prof S Eyre, Prof A Morris

Year round applications PhD Research Project Self-Funded PhD Students Only

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Circadian mechanisms in psoriasis: therapeutic opportunities

The University of Manchester Faculty of Biology, Medicine and Health

Hallmark features of psoriasis symptoms vary through time, suggesting an important role for circadian circuits in driving disease expression, and offering the potential of chronotherapy. Read more

Supervisors: Dr H Young, Dr I Iqbal, Prof D Ray

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) The emerging fungal order Mucorales: species-specific pathogenic strategies and new diagnostics

The University of Manchester Faculty of Biology, Medicine and Health

Mucormycoses are emerging lethal fungal infections, with striking mortality rates of 50-90% depending on the clinical presentation, infection site and underlying host immune status. Read more

Supervisors: Dr M Bertuzzi, Dr N.V.R Van Rhijn

13 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The University of Manchester Faculty of Biology, Medicine and Health

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

Supervisors: Dr MM Mennon, Prof MH Buch

13 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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(MRC DTP CASE) Understanding Disease Management and Outcomes for Myositis Patients: An International Real-World Study Utilising Multiple Data Sources to Investigate Treatment Patterns, Health-Related Quality of Life, Clinical Outcomes, and Burden of Illness for Patients With Rare Autoimmune Disease

The University of Manchester Faculty of Biology, Medicine and Health

Myositis is a group of rare conditions which present with physical symptoms that can significantly impact a patient’s life. Many patients are permanently disabled due to irreversible muscle damage. Read more

Supervisors: Dr H Chinoy, Dr AO Oldroyd

13 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Parasite responses to host immunity

University of Salford School of Science, Engineering and Environment

Information on this PhD research area can be found further down this page under the details about the Widening Participation Scholarship given immediately below. Read more

Supervisor: Prof J.A. Jackson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Host-microbiome interactions in human skin – implications for wound healing in type 2 diabetes

University of Salford School of Science, Engineering and Environment

Information on this PhD research area can be found further down this page under the details about the Widening Participation Scholarship given immediately below. Read more

Supervisors: Dr J Latimer, Dr S Withers

Year round applications PhD Research Project Self-Funded PhD Students Only

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The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

The University of Manchester Faculty of Biology, Medicine and Health

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more

Supervisors: Dr R Hager, Dr M Harte, Dr J Glazier

Year round applications PhD Research Project Self-Funded PhD Students Only

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Dysfunctional antifungal potency of the respiratory mucosa in COPD

The University of Manchester Faculty of Biology, Medicine and Health

Inhalation of Aspergillus fumigatus spores cause >3,000,000 chronic and >200,000 invasive diseases annually worldwide. Invasive aspergillosis carries a 50% mortality rate overall, but mortality rate approaches 100% if diagnosis is delayed or missed and it is >75% in certain cohorts of patients, such as COPD sufferers. Read more

Supervisors: Dr M Bertuzzi, Dr J.H Herbert, Dr S Gago

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating immune contributions to frontotemporal dementia and motor neuron disease

The University of Manchester Faculty of Biology, Medicine and Health

Frontotemporal dementia (FTD) is the 2nd most common form of dementia affecting younger people, with a typical age of onset in the mid-late 50s. Read more

Supervisors: Dr SR Ryan, Prof D Brough

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identifying critical pathways regulating autoimmunity in immuno-oncology and arthritis patients. Short title: IPADS (Immune PAthways for Drug Side-effects)

The University of Manchester Faculty of Biology, Medicine and Health

Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies (inc. Read more

Supervisors: Dr S Viatte, Prof A Barton, Mr P Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni

The University of Manchester Faculty of Biology, Medicine and Health

Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year. Read more

Supervisors: Dr J Cavet, Dr D Linton

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 20 Immunology PhD Research Projects PhD Projects, Programmes & Scholarships in Manchester

Immunology PhD Research Projects PhD Projects, Programmes & Scholarships in Manchester

We have 20 Immunology PhD Research Projects PhD Projects, Programmes & Scholarships in Manchester

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