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We have 31 Immunology (protein) PhD Projects, Programmes & Scholarships

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Immunology (protein) PhD Projects, Programmes & Scholarships

We have 31 Immunology (protein) PhD Projects, Programmes & Scholarships

Discovery and functional investigation of the shared molecular mechanisms of host immunoregulation by the pathogens that cause malaria and sepsis.

Infectious diseases cause enormous humanitarian and economic burdens worldwide. Designing interventions that prevent, cure, or control many infections is difficult because pathogens have evolved sophisticated ways of subverting host immunity. Read more

MSc by Research: Protein secretion landscapes in human immune cells

Roughly one third of the human genome encodes secretory and membrane proteins. Following synthesis in the endoplasmic reticulum (ER), these proteins are captured into transport vesicles for delivery within the cell. Read more

NIHR Leeds BRC: An interferon diagnostic to inform early detection and prevention strategies in Ana positive CTDs

Type I interferons (IFN) play a role in a wide range of rheumatic and musculoskeletal diseases (RMDs), and strong evidence suggests that measurement of IFN activity could have clinical value, although testing has not progressed into clinical settings. Read more

Molecular Mechanisms of Receptor and Ion Channel Regulation in Pain and Inflammation

Are you ready to delve into the captivating world of molecular signaling and unravel the mysteries of the cardiovascular and nervous systems? We are thrilled to offer an exhilarating PhD opportunity at the forefront of scientific exploration. Read more

MSc by Research: Resolving immune cell proteomes to subcellular resolution

Immune activation triggers dramatic proteome remodelling. Using high sensitivity mass spectrometry we have mapped immune cell proteomes, providing novel insights into immune cell phenotypes and revealing the metabolic and protein synthesis machinery and environmental sensors that shape cell fate. Read more

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Unlocking immune cells with tick-borne pathogens

In this project we will use tick-borne pathogenic bacteria as a molecular tool-kit for unlocking immune cells. These discoveries will help us combat tick-borne disease and provide a basis for manipulating immune cells, impacting on a wide range of diseases. Read more

Designing novel biotherapeutics for effective and targeted treatment of cancer (SACHDEVAA_U24BIGC)

Primary supervisor - Dr Amit Sachdeva. Secondary supervisor - Prof Andy Cammidge. Over the last decade, several antibody-based biotherapeutics have been developed for treatment of cancer. Read more

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