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We have 29 Genetics PhD Research Projects PhD Projects, Programmes & Scholarships in Bristol

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Genetics PhD Research Projects PhD Projects, Programmes & Scholarships in Bristol

We have 29 Genetics PhD Research Projects PhD Projects, Programmes & Scholarships in Bristol

University of Bristol

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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School
Genome wide association studies (GWAS) have discovered many genetic associations for traits and diseases. However, most GWAS signals reside in non-coding regions (outside genes), and it is likely that GWAS variants confer their effects through modulating regulatory mechanism. Read more
 Supervisor: Dr J Min
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School
Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more
 Supervisors: Dr J Min, Dr E Hannon, Prof J MIll, Dr GL Leyden
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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The genetics of human scarring – cross-cutting approaches to the understanding of human wound repair.

University of Bristol Bristol Medical School
Rationale. Repair of adult tissues involves a complex interplay of several key cell lineages and inevitably leads to formation of a fibrotic collagenous scar. Read more
 Supervisors: Prof N Timpson, Prof P Martin
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Harnessing genetics of DNA methylation to elucidate molecular mechanisms underlying human phenotypes.

University of Bristol Bristol Medical School
Rationale. GWAS studies have discovered many genetic associations for traits and diseases, but it has been difficult to elucidate the functional consequences of these variants. Read more
 Supervisors: Dr J Min, Prof C Relton, Prof J MIll, Dr E Hannon, Dr G Hemani, Prof T Gaunt, Dr B Heijmans, Dr J Bell
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Understanding psychiatric outcomes in children born with cleft lip and/or palate using genetics

University of Bristol Bristol Medical School
Rationale. Cleft of the lip and/or palate is a common birth defect worldwide and occurs at a rate of one in 650 live births in the UK. Read more
 Supervisors: Dr E Stergiakouli, Dr S Lewis, Prof M J Owen, Dr M van den Bree
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Younger, happier and more productive plants: using developmental genetics to improve herb yields and quality

University of Bristol School of Biological Sciences
If you’ve ever grown coriander at home you’ll have noticed that once the plant flowers it no longer produces the leaves used for seasoning. Read more
 Supervisor: Dr J Fouracre
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Funded PhD - Determining the genetic and circadian basis of bipolar disorder

University of Bristol School of Physiology, Pharmacology & Neuroscience
This project will be part of the University of Bristol - University of Kent Cotutelle Programme. It will be jointly supervised by Prof James Hodge (http://www.bristol.ac.uk/phys-pharm-neuro/people-new/hodge/) and Dr Alice French at the University of Bristol, and by Prof Gurprit Lall at University of Kent. Read more
 Supervisors: Prof J Hodge, Dr AF French
 12 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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The genetic map of human molecular phenotypes

University of Bristol Bristol Medical School
Rationale. Genome wide associations studies (GWASs) have discovered many genetic associations with a large range of human traits, but the functional consequences of GWAS signals often remain elusive, as most GWAS signals reside in non-coding genomic regions. Read more
 Supervisors: Dr J Min, Dr G Hemani, Dr JH Hawe
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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An investigation of the causal relationship and genetic overlap between sleep traits and physical and mental health using Mendelian randomization

University of Bristol Bristol Medical School
Rationale. Sleep has long been known to play a role in physical and mental wellbeing and sleep disruption has been observed to co-occur with a number of health conditions including. Read more
 Supervisors: Dr S Lewis, Dr MR Renteria, Dr HJ Jones
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Identifying causal pathways to disease using DNA methylation predicted blood traits.

University of Bristol Bristol Medical School
Project Background. Blood cell types have been implicated in pathogenesis of chronic diseases. Genome wide association studies have identified thousands of variants associated with blood trait variation. Read more
 Supervisors: Dr J Min, Dr E Hannon, Prof J MIll
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Funded PhD - The mechanisms of cognition in bees and flies

University of Bristol School of Physiology, Pharmacology & Neuroscience
This project will be part of the Bristol-Macquarie Cotutelle Programme, funded by EPSRC. Read more
 Supervisor: Prof J Hodge
 1 August 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MScR - Determining the genetic and circadian basis of bipolar disorder using Drosophila

University of Bristol School of Physiology, Pharmacology & Neuroscience
Circadian rhythms and sleep are evolutionarily conserved from fruit flies (Drosophila) and are fundamental as well as vital to biology and health (Jagannath et al., 2017; Menet and Rosbash, 2011). Read more
 Supervisor: Prof J Hodge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MScR - In vivo characterisation of novel risk genes for Alzheimers disease identified by Genome Wide Association Studies

University of Bristol School of Physiology, Pharmacology & Neuroscience
Genome Wide Association Studies (GWAS) for Alzheimer’s disease (AD) have identified a number of genes that are significantly associated with the disease (van der Kant et al., 2019). Read more
 Supervisor: Prof J Hodge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Endothelial glycocalyx damage as a therapeutic target in sepsis-associated Acute Kidney Injury

University of Bristol Bristol Medical School
Sepsis is the leading cause of acute kidney injury (sAKI), associated with high morbidity and mortality.1,2 Unfortunately, there is no treatment for sAKI, current therapies are nonspecific and supportive of the vital organ systems in the hope the kidney will recover. Read more
 Supervisor: Prof S Satchell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Estimating the global cancer burden due to low levels of physical activity

University of Bristol Bristol Medical School
Rationale. Around 40% of all cancers are thought to be avoidable by modification of lifestyle factors. Obesity has been found to be a risk factor for several cancers and was estimated to have caused around 3.6% of all new cancers which occurred in 2012. Read more
 Supervisors: Dr S Lewis, Prof R Martin, Dr R Pulsford, Prof R Jago, Dr FB Bray
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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