Genetics PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

We have 11 Genetics PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

Probing Death Decisions from Morphogen Gradient Fields

University of Liverpool Department of Molecular and Clinical Cancer Medicine

Morphogen gradient scaling is one of the hottest fields in developmental biology at the moment. Scaling is fundamental, explaining how the machinery that controls pattern formation in development (the morphogens) can adapt, so that organs of different sizes show morphological structures which are proportioned. Read more

Supervisor: Dr MM Merino

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

University of Liverpool Institute of Life Course and Medical Sciences

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

Supervisor: Dr VPV Pekovic-Vaughan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Why do cancers cells re-express meiotic SYCP1 protein?

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The aim of meiosis is to generate gametes by recombining the chromosomes and reducing the genome from diploid to haploid. However, in mitosis haploid genome and recombination have catastrophic, oncogenic outcomes. Read more

Supervisor: Dr U McClurg

Year round applications PhD Research Project Self-Funded PhD Students Only

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The Role of Nutrition and Exercise in Physical and Cognitive Function (such as sarcopenia and frailty), utilizing clinical, metabolomic, proteomic, and gut microbiota data

University of Liverpool Institute of Life Course and Medical Sciences

Physical frailty is a result of hallmarks of aging, where gut microbiome (GM) dysbiosis and dietary pattern play a significant role. Read more

Supervisor: Dr M Isanejad

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using single cell transcriptomic and blood proteomic data to understand how pancreatic cancer causes diabetes and to find ways to detect the cancer earlier

University of Liverpool Department of Molecular and Clinical Cancer Medicine

Pancreatic cancer is the deadliest of the common cancers. Five-year survival remains low at 12%. Sadly for 80% of patients, by the time their cancer is diagnosed it has spread to distant organs making them ineligible for potentially curative surgery. Read more

Supervisor: Prof E Costello

23 May 2024 PhD Research Project Self-Funded PhD Students Only

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Chromatin regulation of oncogenic transcription and replication stress: mechanism and functional implications in acute myeloid leukemia

University of Liverpool Institute of Systems, Molecular and Integrative Biology

This project focuses on the molecular mechanisms promoting acute myeloid leukaemia (AML), a disease of great unmet need. AML is an aggressive blood and bone marrow cancer characterized by abnormal proliferation and differentiation of myeloid cells. Read more

Supervisors: Dr M Papamichos Chronakis, Prof D MacEwan, Dr A Kanhere

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the impact of galectin-ligand interaction on cancer cell resistance to chemotherapeutic treatment

University of Liverpool Institute of Life Course and Medical Sciences

Galectins are multifunctional carbohydrate-binding proteins that are expressed by many types of human cells. Changes of galectin expression commonly occur in cancer (e.g. Read more

Supervisor: Prof LG Yu

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using pre-clinical models of disease to define new targets to slow joint degeneration in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences

The main overall aim of this project is to understand mechanisms of joint degeneration during osteoarthritis progression in order to define new targets for therapy. Read more

Supervisor: Dr B Poulet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the cellular functions of Trappc9 in brain development and microcephaly

University of Liverpool Institute of Systems, Molecular and Integrative Biology

This PhD project will investigate the cellular functions of the Trafficking protein particle complex subunit 9 (Trappc9) and its roles in brain development. Read more

Supervisors: Dr A Plagge, Dr T Zech

Year round applications PhD Research Project Self-Funded PhD Students Only

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Engineering more water-use efficient crops: functional genomics of CO2 fixation during Crassulacean acid metabolism

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The world is getting hotter and drier due to climate change, and the human population is growing rapidly. Furthermore, it has been predicted that we will need to increase crop yields by 50 - 70 % by 2050 in order to feed the predicted 9 - 10 billion people. Read more

Supervisors: Dr J Hartwell, Dr P Walley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Mechanisms controlling gene expression in hypoxia and inflammation

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Oxygen is one of the most important molecules for life. Every member of the animal kingdom depends on oxygen to help metabolize its food and drive many critical processes in metabolism. Read more

Supervisor: Prof S Rocha

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 11 Genetics PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

Genetics PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

We have 11 Genetics PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

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