Genetics (cancer drugs) PhD Projects, Programmes & Scholarships

We have 7 Genetics (cancer drugs) PhD Projects, Programmes & Scholarships

Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute

Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more

Supervisors: Dr M Secrier, Dr L Cottone

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Evaluating the role of circulating proteins in cancer risk and progression using genetic and observational approaches

University of Bristol Bristol Medical School

Rationale. Circulating proteins play fundamental roles in biology and disease aetiology, including development of cancer, and are the direct targets of many drugs (1). Read more

Supervisors: Prof R Martin, Dr JY Yarmolinsky, Dr P Haycock

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

University of Leeds Faculty of Medicine and Health

Cystic fibrosis (CF) is associated with an accentuated inflammatory response to bacterial lipopolysaccharides (LPS), increased resting energy expenditure and a higher than expected prevalence of gastrointestinal and other malignancies. Read more

Supervisors: Prof D Peckham, Prof D Jayne, Dr S Savic, Miss LR Caley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Fully funded PhD studentship in mechanisms of cancer heterogeneity and drug sensitivity

Ariel University Department of Molecular Biology

Treatment of cancer with drugs that cause DNA damage often leads to development of the drug tolerance. Recently, we uncovered a novel mechanism of such an adaptation that associates with active generation of hundreds of thousand mutations in chromosomes that prevent drug-triggered DNA damage. Read more

Supervisor: Prof M Sherman

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Using chemical-genetics to inhibit and characterise “undruggable” enzymes

University of Dundee School of Medicine

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more

Supervisors: Dr T Nasim, Dr M Najafzadeh

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 7 Genetics (cancer drugs) PhD Projects, Programmes & Scholarships

Genetics (cancer drugs) PhD Projects, Programmes & Scholarships

We have 7 Genetics (cancer drugs) PhD Projects, Programmes & Scholarships

Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

Evaluating the role of circulating proteins in cancer risk and progression using genetic and observational approaches

Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

Fully funded PhD studentship in mechanisms of cancer heterogeneity and drug sensitivity

Using chemical-genetics to inhibit and characterise “undruggable” enzymes

Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

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