Genetics (dundee) PhD Projects, Programmes & Scholarships

We have 26 Genetics (dundee) PhD Projects, Programmes & Scholarships

Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Leveraging novel automated diagnostic pathways with augmented precision medicine approaches for the early detection and risk stratification of liver disease

University of Dundee School of Medicine

Liver disease represents one of the fastest-growing causes of morbidity and mortality in the world. The principle aetiological variants are contained within the new nomenclature of steatotic liver disease (SLD). Read more

Supervisors: Dr P Brennan, Prof J F Dillon, Dr M Al-Khairalla

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Using chemical-genetics to inhibit and characterise “undruggable” enzymes

University of Dundee School of Medicine

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Utility of in silico prediction tools to aid variant interpretation

University of Dundee School of Medicine

Accurate variant interpretation represents is essential for the successful implementation of genetic testing in the clinical setting. Read more

Supervisor: Dr P Newey

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Feel the tension – how does S-acylation of OSCA ion channels regulate responses to environmental change in plants?

University of Dundee School of Life Sciences

Plants, being sessile organisms, must sense and respond to environmental change, such as temperature or drought, without being able to move. Read more

Supervisors: Dr P Hemsley, Prof U Zachariae, Prof M Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Targeted protein degradation in plants – developing “Green PROTACs” for functional analysis of lethal genes

University of Dundee School of Life Sciences

Climate change is one of the biggest threats to global food production, leading to unpredictable weather patterns and geographical migration of pathogens. Read more

Supervisor: Dr P Hemsley

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Speeding up the plant microbiota: investigating the impact of speed breeding on host-microbe interactions in the barley rhizosphere

University of Dundee School of Life Sciences

Feeding a growing world population amid climatic modifications and international conflicts represents an unprecedent challenge for crop production. Read more

Supervisors: Dr D Bulgarelli, Dr C Campoli

Year round applications PhD Research Project Self-Funded PhD Students Only

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BARIToNE: Deep Seeded: Improving barley for deeper sowing (Project code 24I)

The James Hutton Institute PhD Opportunities

Supervisors. Lead supervisor - Dr Sarah McKim, University of Dundee. Second supervisor - Dr Chiara Campoli, James Hutton Institute. Read more

Supervisors: Dr S McKim, Dr C Campoli, Dr L Ramsay, Dr D Sparkes

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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BARIToNE: Deep Seeded: Improving barley for deeper sowing (Project code 24I)

University of Dundee School of Life Sciences

Supervisors. Lead supervisor - Dr Sarah McKim, University of Dundee. Second supervisor - Dr Chiara Campoli, James Hutton Institute. Read more

Supervisors: Dr S McKim, Dr C Campoli, Dr L Ramsay, Dr D Sparkes

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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MSc by Research: Signaling pathways controlling epidermal development in cereals

University of Dundee School of Life Sciences

Plants living on land face brutal threats from pests, dehydration and temperature. To survive and thrive, land plants evolved a waxy ‘cuticle’ and distinctive epidermal cells such as gas pores and defensive barbs. Read more

Supervisor: Dr S McKim

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: The Generation Gap – understanding tissue communication during grain development

University of Dundee School of Life Sciences

Cereal grain provides more calories than any other source to our diet, making grain production vital to food security. We study grain development in barley, a globally important cereal, and a powerful genetic model system. Read more

Supervisor: Dr S McKim

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Genetic interactions and novel genes that regulate lignin biosynthesis and straw quality in barley

University of Dundee School of Life Sciences

Lignin is a major component of plant cell walls, and has a significant influence on the digestibility and uses of plant biomass. The lignin biosynthesis pathway has been one of the most intensively studied. Read more

Supervisor: Prof C Halpin

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

University of Dundee School of Life Sciences

T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more

Supervisor: Dr T Ly

Year round applications PhD Research Project Self-Funded PhD Students Only

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