Genetics (mass spectrometry) PhD Projects, Programmes & Scholarships

We have 6 Genetics (mass spectrometry) PhD Projects, Programmes & Scholarships

Using single cell transcriptomic and blood proteomic data to understand how pancreatic cancer causes diabetes and to find ways to detect the cancer earlier

University of Liverpool Department of Molecular and Clinical Cancer Medicine

Pancreatic cancer is the deadliest of the common cancers. Five-year survival remains low at 12%. Sadly for 80% of patients, by the time their cancer is diagnosed it has spread to distant organs making them ineligible for potentially curative surgery. Read more

Supervisor: Prof E Costello

23 May 2024 PhD Research Project Self-Funded PhD Students Only

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Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Manganese is essential to human health and development. However, excess manganese is neurotoxic causing manganism, a neurodegenerative disorder characterised by dystonia-parkinsonism. Read more

Supervisors: Dr K Tuschl, Dr P Mills, Dr WH Heywood

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Glycosylation in Microalgal Host Cells

University of Sheffield Department of Chemical & Biological Engineering

Microalgae have generated increasing interest as microbial cell factories to produce therapeutics proteins. This is because they can grow on very cheap media and their GRAS (generally regarded as safe) status means they are a fantastic option for the production of therapeutics that can be administered orally. Read more

Supervisors: Dr J Pandhal, Dr C Evans

Year round applications PhD Research Project Self-Funded PhD Students Only

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Chromatin remodelling complexes in human brain development

King’s College London Faculty of Life Sciences & Medicine

Chromatin regulators are a group of proteins that control the way the rest of the genome is opened up and “read” by the cellular machinery, with fundamental roles in development and disease. Read more

Supervisors: Dr CD Dias, Dr JA Atherton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating monogenic disorders of the protein synthesis machinery

The University of Manchester Faculty of Biology, Medicine and Health

Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more

Supervisors: Dr P Kasher, Dr S Banka, Prof G D Pavitt

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using chemical-genetics to inhibit and characterise “undruggable” enzymes

University of Dundee School of Medicine

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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We have 6 Genetics (mass spectrometry) PhD Projects, Programmes & Scholarships

Genetics (mass spectrometry) PhD Projects, Programmes & Scholarships

We have 6 Genetics (mass spectrometry) PhD Projects, Programmes & Scholarships

Using single cell transcriptomic and blood proteomic data to understand how pancreatic cancer causes diabetes and to find ways to detect the cancer earlier

Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Glycosylation in Microalgal Host Cells

Chromatin remodelling complexes in human brain development

Investigating monogenic disorders of the protein synthesis machinery

Using chemical-genetics to inhibit and characterise “undruggable” enzymes

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