Genetics (retinal) PhD Projects, Programmes & Scholarships

We have 6 Genetics (retinal) PhD Projects, Programmes & Scholarships

Understanding the role of pigmentation in retinal and vision development

University of Leicester School of Psychology and Vision Sciences

Establishing structure-function correlations in vision development . The aim of this project is to develop methods to study the relationship between pigmentation and vision development in humans and zebrafish. . Read more

Supervisors: Dr M Thomas, Dr W Norton, Dr J McDearmid

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Identifying variants impacting splicing of 5’ and 3’ UTRs and underpinning inherited retinal disease

The University of Manchester Faculty of Biology, Medicine and Health

Genomic variation that impacts splicing is well established as a cause of genomic disorders, but is almost exclusively limited to protein-coding exons and introns intersecting protein-coding exons. Read more

Supervisors: Dr J Ellingford, Prof R O'Keefe

15 June 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Genetics: Unravelling the Norrin/beta-catenin signaling pathway and its role in retinal angiogenesis and blindness

University of Leeds Faculty of Medicine and Health

Our previous work on the genetic analysis of individuals with the inherited retinal disease Familial Exudative Vitreoretinopathy (FEVR), has helped identify a new angiogenesis pathway, the Norrin/beta-catenin pathway. Read more

Supervisors: Dr C Toomes, Dr J Bond, Dr S Bell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Optogenetic sculpting of next-generation organoids for disease modelling of congenital malformations including spina bifida

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

The ability to generate human induced pluripotent stem cells (iPSC) from adult cell types has revolutionised regenerative medicine research. Read more

Supervisors: Dr G Galea, Prof J Sowden

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Common genetic origins of visual and neurocognitive disorders

University of York York Biomedical Research Institute

There is emerging evidence that apparently distinct neurodegenerative diseases have common genetic origins. For example, genes such as ARMS2 and HTRA1, which are fundamental to regulating neuronal health, are implicated in both dementia and diseases of the retina (particularly age-related macular degeneration). Read more

Supervisors: Prof A Wade, Prof A Morland, Dr H Baseler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

University of Leeds Faculty of Medicine and Health

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more

Supervisor: Dr M Ali

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 6 Genetics (retinal) PhD Projects, Programmes & Scholarships

Genetics (retinal) PhD Projects, Programmes & Scholarships

We have 6 Genetics (retinal) PhD Projects, Programmes & Scholarships

Understanding the role of pigmentation in retinal and vision development

Identifying variants impacting splicing of 5’ and 3’ UTRs and underpinning inherited retinal disease

Genetics: Unravelling the Norrin/beta-catenin signaling pathway and its role in retinal angiogenesis and blindness

Optogenetic sculpting of next-generation organoids for disease modelling of congenital malformations including spina bifida

Common genetic origins of visual and neurocognitive disorders

Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

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