Pharmacy (therapy) PhD Projects, Programmes & Scholarships

Year round applications PhD Research Project Self-Funded PhD Students Only

Research Group: Pharmacology and Experimental Therapeutics

Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Supervisor: Dr T Nasim

Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

Supervisor: Dr Muhammad Wahajuddin

Research Group: Institute of Cancer Therapeutics

Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Freeze-dried bacteriophage formulations against antibiotic-resistant bacteria

Supervisors: Dr T Skvortsov, Prof K Malcolm, Dr V Kett

Antimicrobial resistance (AMR) presents a significant global public health issue. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

The University of Manchester Department of Physics and Astronomy

How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Supervisor: Prof J Lu

28 June 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Cardiff University Cardiff School of Pharmacy and Pharmaceutical Sciences

Small molecule cancer drug discovery targeting resistant disease.

Despite continuous advances in targeted cancer therapy in recent years, there remains a major challenge to combat drug resistance and poor levels of efficacy in areas of unmet medical need, such as advanced colorectal and breast cancer. Read more

Supervisor: Prof A Westwell

17 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

Supervisors: Dr T Nasim, Dr M Najafzadeh

Research Group: Pharmacology and Experimental Therapeutics

Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Development of antibody-drug conjugates (ADCs) for oncology indications

Supervisors: Prof K Pors, Dr Muhammad Wahajuddin, Prof R Falconer

Research Group: Institute of Cancer Therapeutics

A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

Supervisors: Prof R Falconer, Prof P Loadman

Research Group: Institute of Cancer Therapeutics

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Therapeutic resolution of BMPR2-mediated signalling defects in pulmonary arterial hypertension (PAH)

Supervisors: Dr T Nasim, Dr R Gopalan

Research Group: Pharmacology and Experimental Therapeutics

Pulmonary arterial hypertension (PAH) is an incurable and devastating disease and death occurs within 2.5 years of diagnosis. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Supervisor: Prof L Martin

Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Peptide-based nanoparticles for brain targeted gene delivery.

Supervisors: Dr E McErlean, Prof H McCarthy

Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Genetic Engineering of Immune Effector Cells for CAR therapies using a Peptide Technology

Supervisors: Dr E McErlean, Prof H McCarthy

Chimeric antigen receptor (CAR)-T therapies have demonstrated remarkable treatment outcomes and several CAR-T therapies now approved for treatment of haematological malignancies. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

Year round applications PhD Research Project Self-Funded PhD Students Only

One in two people will develop cancer in their lifetime and it is a leading cause of death. While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. . Read more

Supervisor: Dr N Buckley

Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

Year round applications PhD Research Project Self-Funded PhD Students Only

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

Supervisor: Dr G Laverty

University of Portsmouth School of Pharmacy and Biomedical Sciences

Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

Applications are invited for a self-funded, 3 year full-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. Read more

Supervisors: Dr R Hadianamrei, Dr S Hafizi

Year round applications PhD Research Project Self-Funded PhD Students Only