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We have 23 Structural Biology (design for) PhD Projects, Programmes & Scholarships

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Structural Biology (design for) PhD Projects, Programmes & Scholarships

We have 23 Structural Biology (design for) PhD Projects, Programmes & Scholarships

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A 3D-Printed Blood-Brain-Barrier-on-a-Chip for Agrochemical Permeability Studies – CASE Studentship

University of Liverpool Department of Physics
The blood-brain barrier (BBB) tightly regulates the flow of material between the bloodstream and the brain. One of the big problems faced by a range of sectors, from pharmaceuticals to agrochemicals, is understanding how compounds interact with and cross this barrier. Read more
 Supervisors: Dr J Forth, Dr D Dickens
 1 June 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Development of LA1011 for high affinity binding to Hsp90 for use towards healthy ageing in patients showing Alzheimer’s symptoms

University of Sussex School of Life Sciences
  Research Group: Biochemistry
With 50 million global cases of Alzheimer’s disease (AD) and care costs of 1 trillion UK pounds (expected to triple by 2050), there is a pressing need to slow disease progression, sustain productive lives and reduce costs. Read more
 Supervisor: Dr C Prodromou
 5 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Maastricht University Cardiovascular Research Institute Maastricht (CARIM)
Applications can only be submitted via our website. The specific position for Doctoral Candidate 6 (DC6) in the consortium, which is part of Work Package 2 (WP2), aims. Read more
 Supervisor: Dr G Nicolaes
 30 April 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Sustainable Commodity Chemicals through Enzyme Engineering & Design (SuCCEED) - 4 posts available

The University of Manchester Department of Chemistry
SuCCEED is a BBSRC-funded Prosperity Partnership multi-million project between The University of Manchester and Shell. Commodity chemicals are produced on a global scale and normally derived from finite geological sources. Read more
 Supervisors: Dr N Dixon, Dr J Esteban Serrano, Prof A Green, Prof D Leys, Dr V Spallina, Prof M Turner, Dr J Winterburn
 30 June 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health
We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more
 Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Design and Folding of beta barrel membrane proteins

University of Leeds Faculty of Biological Sciences
The cell walls of Gram negative bacteria are packed with b-barrel outer membrane proteins (OMPs) whose function are essential for bacterial growth and virulence. Read more
 Supervisors: Prof S E Radford, Prof D B Brockwell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design and engineering of peptides and proteins to create artificial metalloenzymes

Cardiff University Cardiff School of Chemistry
The Rhys lab is an exciting new lab looking to recruit new students to design and engineer peptides and proteins for new applications (rhyslab.com). Read more
 Supervisor: Dr G Rhys
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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4-year PhD Studentship: Combatting bacterial zoonoses through multi-disciplinary studies of virulence factors

University of Bristol Bristol Veterinary School
Vector-borne diseases, including bacterial zoonoses, pose a significant threat to human and animal health and to livestock industries, particularly in low and middle-income countries. Read more
 Supervisor: Dr T Cogan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Building new nano-biosensors for healthcare: Linking biology to the world of carbon nanotechnology through synthetic biology

Cardiff University Cardiff School of Biosciences
Project Descriptions. Proteins are nature’s very own molecular machines carrying out functions ranging from catalysis to molecular recognition to energy conversion. Read more
 Supervisors: Prof D Jones, Dr M Palma, Dr WK Kelton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Targeting the mechanism of small GTPase splice variant RAC1B using ligand design

The University of Manchester Faculty of Biology, Medicine and Health
RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more
 Supervisors: Dr RB Bryce, Dr S Butterworth, Dr T Jowitt, Dr A Ucar
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Better together: constructing tuneable fluorescent protein sensors for cellular imaging of protein-protein interactions

Cardiff University Cardiff School of Biosciences
Project Description. Protein-protein interactions (PPIs) commonly occur in biology with ~650,000 contributing to processes critical to human life. Read more
 Supervisors: Prof D Jones, Dr PD Watson, Dr G Menzies, Dr R Clarkson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Glueing proteins together with small molecules

University of Dundee School of Life Sciences
Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more
 Supervisor: Prof A Ciulli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Viral-surface interactions studied by vibrational sum-frequency spectroscopy

The University of Manchester Department of Materials
The recent COVID-19 pandemic, and in particular fomite transmission of the virus, led to a lot of interest in how viral particles attached to surfaces, their survival times on different materials and how they transferred to hosts. Read more
 Supervisors: Dr A Thomas, Dr R Lindsay
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology
What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more
 Supervisors: Dr JF Fox, Dr JH Hodgkinson
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Enhancing Insight into Variations in Virulence Among Avian influenza Viruses Infecting Poultry

The Pirbright Institute Pirbright Laboratory, Surrey, Outer London
This studentship is open to science graduates with, or who anticipate obtaining, at least a 2:1 or equivalent in a relevant biological subject in their undergraduate degree, or a Masters degree - subject to university regulations. Read more
 Supervisors: Prof M Iqbal, Prof J Daly
 30 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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