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We have 49 Structural Biology (development) PhD Projects, Programmes & Scholarships

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Structural Biology (development) PhD Projects, Programmes & Scholarships

We have 49 Structural Biology (development) PhD Projects, Programmes & Scholarships

Development of LA1011 for high affinity binding to Hsp90 for use towards healthy ageing in patients showing Alzheimer’s symptoms

  Research Group: Biochemistry
With 50 million global cases of Alzheimer’s disease (AD) and care costs of 1 trillion UK pounds (expected to triple by 2050), there is a pressing need to slow disease progression, sustain productive lives and reduce costs. Read more

Advanced Electron Paramagnetic Resonance (EPR) spectroscopy – method development and applications

Electron Paramagnetic Resonance (EPR) spectroscopy is a magnetic resonance technique that is exclusively and exquisitely sensitive to unpaired electrons that are found in radicals and paramagnetic metal complexes. Read more

Chromatin remodelling complexes in human brain development

Chromatin regulators are a group of proteins that control the way the rest of the genome is opened up and “read” by the cellular machinery, with fundamental roles in development and disease. Read more

Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

Novel glycoprotease discovery and characterisation for enhanced detergent performance

In this exciting joint academia-industry project the student will exploit metagenomes and the huge untapped capacity of the human gut microbiota to breakdown glycoconjugates to discover novel protease enzymes that can potentially increase the performance and environmental sustainability of leading P&G automatic dishwashing brands. Read more

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