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Structural Biology (it) PhD Projects, Programmes & Scholarships

We have 57 Structural Biology (it) PhD Projects, Programmes & Scholarships

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How does myosin 10 contribute to filopodia formation and stability?

University of Leeds Faculty of Biological Sciences
How do cells make filopodia? Filopodia are thin protrusions that act as pathfinders in cell migration, helping cells to sense where to go, and pulling cells through the extracellular matrix, especially important in driving cancer cell metastasis. Read more
 Supervisors: Prof M Peckham, Dr D Tomlinson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

University of Leeds Faculty of Biological Sciences
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more
 Supervisor: Dr J Boyes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing novel light-induced in-situ Electron Paramagnetic Resonance (EPR) methods

The University of Manchester Department of Chemistry
Light-induced in-situ Electron Paramagnetic Resonance (EPR) studies are a growing field in both continuous wave and pulsed EPR. It can be used to monitor photoactivated chemical and biochemical reactions involving radical reagents, projects or intermediates. Read more
 Supervisors: Dr A Bowen, Prof D Collison, Dr A Golovanov
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

The University of Manchester Faculty of Biology, Medicine and Health
Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more
 Supervisors: Dr A Politis, Dr CP Pliotas
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

University of York York Biomedical Research Institute
Viruses, these tiny but potent life forms, are all around us, infecting various organisms and directly affecting human health. Although in most cases, viral infection is not life threatening, in the minority of cases it leads to long-term disorders including cancer. Read more
 Supervisors: Prof F Antson, Dr J Gordeeva, Dr P Bardy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies

University of Leicester Molecular and Cell Biology
Whether a cell dies or not has profound consequences on health and disease. In healthy tissue, cells that acquire high levels of genetic damage are safely removed via a process of programmed cell death. Read more
 Supervisor: Dr JF Fox
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Join Our Quest to Unravel the Secrets of Eukaryotic Genomes!

University of Leicester Molecular and Cell Biology
We're on the lookout for passionate PhD students who are eager to delve deep into the mysteries of our DNA. Our quest? To understand the subtle changes that determine how our genes function, both in sickness and in health. Read more
 Supervisor: Dr T Schalch
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Taking Light Induced Electron Paramagnetic Resonance In Cell for Biological Structural Determination

The University of Manchester Department of Chemistry
Studying the structure of proteins and other biological systems is an important step in understanding their function. Most structural studies are conducted in environments that are far away from native conditions, such as those found inside a cell. Read more
 Supervisors: Dr A Bowen, Dr J Rowbotham, Dr I Riddell, Dr D Heyes
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Novel strategies for the diagnosis and treatment of snakebites

University of Reading School of Pharmacy
Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more
 Supervisor: Prof SV Vaiyapuri
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Obtaining insights into how a signalling hub protein Ras activates multiple effectors

University of Leicester Molecular and Cell Biology
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more
 Supervisors: Dr K Tanaka , Dr R Mahen
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Molecular Glues as Novel Tools for Tackling Big Challenges in Human Health

University of Leicester Department of Chemistry
Background. The need for new medicines is greater than ever because of an ageing population and the complex clinical challenges brought about by drug resistance and/or side effects. Read more
 Supervisors: Dr RD Doveston, Prof S Macip
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Molecular characterization of Sam68-driven cytoskeletal reorganization

University of Leicester Molecular and Cell Biology
The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more
 Supervisors: Dr C Dominguez, Prof A Fry
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Elucidating the molecular mechanisms of intrinsic antibiotic resistance in bacterial pathogens

University of Leeds Faculty of Biological Sciences
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to the average human lifespan. Read more
 Supervisor: Prof A O'Neill
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Targeting the mechanism of small GTPase splice variant RAC1B using ligand design

The University of Manchester Faculty of Biology, Medicine and Health
RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more
 Supervisors: Dr RB Bryce, Dr S Butterworth, Dr T Jowitt, Dr A Ucar
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Feel the tension – how does S-acylation of OSCA ion channels regulate responses to environmental change in plants?

University of Dundee School of Life Sciences
Plants, being sessile organisms, must sense and respond to environmental change, such as temperature or drought, without being able to move. Read more
 Supervisors: Dr P Hemsley, Prof U Zachariae, Prof M Knight
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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