Structural Biology (online) PhD Projects, Programmes & Scholarships

We have 46 Structural Biology (online) PhD Projects, Programmes & Scholarships

Biozentrum PhD Fellowships in life sciences

The Biozentrum of the University of Basel, Switzerland, announces the opening of the Winter Call 2023_24 for the Biozentrum PhD Fellowships. Read more

Funded PhD Programme (Students Worldwide) Switzerland PhD Programme

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(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

The University of Manchester Faculty of Biology, Medicine and Health

Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more

Supervisors: Dr A Politis, Dr CP Pliotas

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Targeting the mechanism of small GTPase splice variant RAC1B using ligand design

The University of Manchester Faculty of Biology, Medicine and Health

RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more

Supervisors: Dr RB Bryce, Dr S Butterworth, Dr T Jowitt, Dr A Ucar

Year round applications PhD Research Project Self-Funded PhD Students Only

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4-year PhD Studentship: Combatting bacterial zoonoses through multi-disciplinary studies of virulence factors

University of Bristol Bristol Veterinary School

Vector-borne diseases, including bacterial zoonoses, pose a significant threat to human and animal health and to livestock industries, particularly in low and middle-income countries. Read more

Supervisor: Dr T Cogan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Supervisors: Dr M Young, Dr J Parker

Year round applications PhD Research Project Self-Funded PhD Students Only

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Building new nano-biosensors for healthcare: Linking biology to the world of carbon nanotechnology through synthetic biology

Cardiff University Cardiff School of Biosciences

Project Descriptions. Proteins are nature’s very own molecular machines carrying out functions ranging from catalysis to molecular recognition to energy conversion. Read more

Supervisors: Prof D Jones, Dr M Palma, Dr WK Kelton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Better together: constructing tuneable fluorescent protein sensors for cellular imaging of protein-protein interactions

Cardiff University Cardiff School of Biosciences

Project Description. Protein-protein interactions (PPIs) commonly occur in biology with ~650,000 contributing to processes critical to human life. Read more

Supervisors: Prof D Jones, Dr PD Watson, Dr G Menzies, Dr R Clarkson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the interaction of La related proteins with colliding ribosomes

The University of Manchester Faculty of Biology, Medicine and Health

Translation of mRNA into proteins is a critical cellular biological process for all life. This requires ribosomes to act with an array of translation factors to decode mRNA sequences. Read more

Supervisors: Prof G D Pavitt, Dr A Roseman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Alpha-synuclein amyloid in Parkinson's disease: using Nanoinjection as a tool to study alpha-synuclein amyloid toxicity inside neurons

University of Leeds Faculty of Biological Sciences

Intraneuronal inclusions known as Lewy bodies are a hallmark of Parkinson’s disease. Amyloid fibrils formed by the misfolding of alpha-synuclein are the principal component of Lewy Bodies. Read more

Supervisors: Dr E W Hewitt, Prof S E Radford, Dr P Actis

Year round applications PhD Research Project Self-Funded PhD Students Only

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Control and inhibition of virus replication

University of Leeds Faculty of Biological Sciences

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more

Supervisor: Dr A.K Tuplin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Delivery and misdelivery of outer membrane proteins to the BAM complex using cryoEM

University of Leeds Faculty of Biological Sciences

The BAM complex folds membrane proteins into the outer membrane of Gram-negative bacteria, proteins whose functions are essential for bacterial viability, pathogenicity and virulence. Read more

Supervisors: Prof N A Ranson, Prof S E Radford

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design and Folding of beta barrel membrane proteins

University of Leeds Faculty of Biological Sciences

The cell walls of Gram negative bacteria are packed with b-barrel outer membrane proteins (OMPs) whose function are essential for bacterial growth and virulence. Read more

Supervisors: Prof S E Radford, Prof D B Brockwell

Year round applications PhD Research Project Self-Funded PhD Students Only

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How does myosin 10 contribute to filopodia formation and stability?

University of Leeds Faculty of Biological Sciences

How do cells make filopodia? Filopodia are thin protrusions that act as pathfinders in cell migration, helping cells to sense where to go, and pulling cells through the extracellular matrix, especially important in driving cancer cell metastasis. Read more

Supervisors: Prof M Peckham, Dr D Tomlinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using cryo-electron microscopy to study large protein complexes that mediate the female post-mating response

University of Leeds Faculty of Biological Sciences

In many animals, male seminal fluid alters female physiology and post-mating behaviour to ensure paternity of the offspring. However, how seminal fluid components elicit these post-mating responses is poorly understood. Read more

Supervisors: Dr J.J.B. Cockburn, Prof R E Isaac

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 46 Structural Biology (online) PhD Projects, Programmes & Scholarships

Structural Biology (online) PhD Projects, Programmes & Scholarships

We have 46 Structural Biology (online) PhD Projects, Programmes & Scholarships

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