Structural Biology (synthesis) PhD Projects, Programmes & Scholarships

We have 9 Structural Biology (synthesis) PhD Projects, Programmes & Scholarships

Discovery of novel antibiotics through synthesis of lab-based (biochem/microbio) and computational microbiology (molecular dynamics/deep generative learning/AI)

University of Portsmouth School of Pharmacy and Biomedical Sciences

As stated by the World Health Organisation (WHO), antimicrobial resistance (AMR) is one of the greatest public health threats facing humanity. Read more

Supervisor: Dr R Draheim

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the interaction of La related proteins with colliding ribosomes

The University of Manchester Faculty of Biology, Medicine and Health

Translation of mRNA into proteins is a critical cellular biological process for all life. This requires ribosomes to act with an array of translation factors to decode mRNA sequences. Read more

Supervisors: Prof G D Pavitt, Dr A Roseman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting the mechanism of small GTPase splice variant RAC1B using ligand design

The University of Manchester Faculty of Biology, Medicine and Health

RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more

Supervisors: Dr RB Bryce, Dr S Butterworth, Dr T Jowitt, Dr A Ucar

Year round applications PhD Research Project Self-Funded PhD Students Only

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Revealing Reactivity in Cancer-Associated Heme Proteins: Novel Time-Resolved Structural Approaches

University of Leicester Molecular and Cell Biology

Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme involved in the degradation of tryptophan to kynurenine. Cancer cells upregulate IDO1 to escape normal immune responses and, in many cases, a high expression of IDO1 is connected to poor prognosis. Read more

Supervisors: Dr HK Kwon, Dr P A Ash

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

University of Leicester Department of Chemistry

Redox properties of metal-containing active sites are critically important to many biocatalytic processes. one third of all proteins contain a redox-active metal, and ca 22% of submissions to the Protein Data Bank contain a transition metal. Read more

Supervisors: Dr PA Ash, Dr H Kwon

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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ThAnoS: thiopeptide antibiotics biosynthesis (GHILAROV_J24DTP)

John Innes Centre Graduate Programme

Background. The acute problem of antimicrobial resistance incentivises us to develop innovative approaches to antibiotic discovery & production. Read more

Supervisor: Dr D Ghilarov

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

University of Leicester Department of Chemistry

Graduate Teaching Assistantship. This is a Graduate Training Assistantship (GTA), which means that you will be required to do some teaching, particularly lab demonstrating, as part of your training. Read more

Supervisor: Dr P Ash

22 April 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Design and engineering of peptides and proteins to create artificial metalloenzymes

Cardiff University Cardiff School of Chemistry

The Rhys lab is an exciting new lab looking to recruit new students to design and engineer peptides and proteins for new applications (rhyslab.com). Read more

Supervisor: Dr G Rhys

Year round applications PhD Research Project Self-Funded PhD Students Only

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Overcoming replication stress–defining new mechanism from archaea to human

University of Nottingham School of Life Sciences

How cells respond to DNA replication stresses (e.g., DNA replication collapse, stalling or hyper-activity) is critical for their survival, and is a hallmark of cancers. Read more

Supervisors: Dr E Bolt, Prof T Allers

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 9 Structural Biology (synthesis) PhD Projects, Programmes & Scholarships

Structural Biology (synthesis) PhD Projects, Programmes & Scholarships

We have 9 Structural Biology (synthesis) PhD Projects, Programmes & Scholarships

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