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We have 28 Biophysics (molecular interactions) PhD Projects, Programmes & Scholarships

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Biophysics (molecular interactions) PhD Projects, Programmes & Scholarships

We have 28 Biophysics (molecular interactions) PhD Projects, Programmes & Scholarships

Machine Learning and Molecular Modelling in Mass Spectrometry

This PhD project will harness the power of computational modelling and machine learning (A.I.) to analyse data obtained by mass spectrometry experiments and predict structural characteristics of biomolecules and their interactions. Read more

Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

Viruses, these tiny but potent life forms, are all around us, infecting various organisms and directly affecting human health. Although in most cases, viral infection is not life threatening, in the minority of cases it leads to long-term disorders including cancer. Read more

Understanding interactions of proteins with polymer-coated nanoparticles

Introduction. Polymer-coated nanoparticles are promising drug delivery vehicles. Multiple functionalities can be embedded into the nanoparticle structure to enable uptake of the drug-like molecules, their targeted delivery and controlled release. Read more

Discovery and functional investigation of the shared molecular mechanisms of host immunoregulation by the pathogens that cause malaria and sepsis.

Infectious diseases cause enormous humanitarian and economic burdens worldwide. Designing interventions that prevent, cure, or control many infections is difficult because pathogens have evolved sophisticated ways of subverting host immunity. Read more

Self-funded PhD- Understanding the molecular mechanism of a bacterial genome defence system and its synergy with CRISPR-Cas

Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well-studied of which are the Restriction-Modification and the CRISPR-Cas enzymes. Read more

Targeting Ras palmitoylation for the treatment of cancer

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Structural investigation of oncogenic splicing factors

More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more

Probing Death Decisions from Morphogen Gradient Fields

Morphogen gradient scaling is one of the hottest fields in developmental biology at the moment. Scaling is fundamental, explaining how the machinery that controls pattern formation in development (the morphogens) can adapt, so that organs of different sizes show morphological structures which are proportioned. Read more

Biophysical explorations of neural crest cell behaviours in development and cancer

Neural crest cells are highly migratory. These cells travel throughout the developing embryo, eventually contributing to most organ systems, including the peripheral nervous system, pigment cells and craniofacial skeleton. Read more

Faculty of Medicine, Masaryk University

The Biomedical Sciences doctoral degree programme has been created through the merging Medical Biology, Anatomy, Histology, Embryology, and Molecular Medicine, which has been designed in the CEITEC MU research centre to be a robust singular study programme consisting of three disciplines (Cell and Tissue Morphology, Biochemistry and Molecular Biology, and Molecular Medicine). Read more

How do RNA-binding proteins control splice site selection? A multi-disciplinary approach

Almost every protein-coding gene in vertebrates can and does express multiple proteins. This is achieved primarily by RNA splicing, which is an essential step in gene expression in mammals and generates incredible diversity. Read more

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