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We have 24 Physiology (cancer research) PhD Projects, Programmes & Scholarships

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Physiology (cancer research) PhD Projects, Programmes & Scholarships

We have 24 Physiology (cancer research) PhD Projects, Programmes & Scholarships

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

  Research Group: Chemistry and Biosciences
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

  Research Group: Chemistry and Biosciences
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more

Neuronal control of appetite: investigating the role of the extracellular matrix in controlling neuronal activity in the hypothalamus

  Research Group: Chemistry and Biosciences
Appetite regulation is complex, and its dysregulation has serious implications for health, being observed in multiple conditions e.g., obesity, anorexia, and type 2 diabetes. Read more

Our Mission: to Educate, Nurture and Discover for the benefit of Human Health

Founded in 1784 as the professional body for surgical training in Ireland, RCSI has evolved in the years since to become one of the world's leading health sciences universities. Read more

Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Read more

Ion channel signalling in cancer cells

Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing. Read more

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