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We have 23 Physiology (signalling) PhD Projects, Programmes & Scholarships

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Physiology (signalling) PhD Projects, Programmes & Scholarships

We have 23 Physiology (signalling) PhD Projects, Programmes & Scholarships

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Biomechanical signalling in human heart disease

University of Melbourne Murdoch Childrens Research Institute
About the Project. The human heart undergoes more than 2 billion beats throughout an individual's lifetime, with its rhythm precisely regulated by signalling events that continuously adapt to the biomechanical stress exerted on the ventricular walls. Read more
 Supervisor: Dr J McNamara
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Investigating the roles that G protein coupled receptors play in hypertension

University of Leicester Molecular and Cell Biology
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
 Supervisor: Dr J Willets
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Ion channel signalling in cancer cells

University of York York Biomedical Research Institute
Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing. Read more
 Supervisor: Dr W Brackenbury
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics
Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more
 Supervisor: Dr RB Burton
 1 July 2024  PhD Research Project  Self-Funded PhD Students Only
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Molecular mechanisms of the increase in maximal aerobic capacity (VO2max) with regular exercise

University of Stirling Faculty of Health Sciences and Sport
  Research Group: PENRG - Physiology Exercise and Nutrition Research Group
Performing regular exercise is crucial for good health and wellbeing, whereas failing to perform sufficient exercise increases the risk of diseases such as cardiovascular disease, type 2 diabetes, cancer, etc. Read more
 Supervisors: Dr N Vollaard, Dr ECR Hall
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Targeting the sweet tooth to curb population-wide sugar intake

University of Nottingham School of Medicine
Excess intake of dietary sugars are a major contributor to obesity, and type 2 diabetes and 82% of people state that taste is the major determinant of what they buy and eat. Read more
 Supervisor: Dr P Aldiss
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MScR - Astrocyte mechanisms in depression

University of Bristol School of Physiology, Pharmacology & Neuroscience
Depression is the most common mental health illness affecting about 20% of the population at least once in their lifetime. Depression has been proposed to be a result of a decreased level of brain monoamines such as serotonin. Read more
 Supervisor: Dr V Mosienko
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of Aquaporins in age related diseases

University of Liverpool Institute of Life Course and Medical Sciences
Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more
 Supervisor: Dr C Staunton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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What is the relevance of hormones made in the brain?

University of Reading Department of Biomedical Sciences
Project Overview: . Read more
 Supervisors: Dr N Vasudevan, Prof P G Knight
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Dimensions of motivation to eat, appetite control and obesity management

University of Leeds Faculty of Medicine and Health
This fully funded PhD place provides an exciting opportunity to pursue postgraduate research in appetite, energy balance and obesity research. . Read more
 Supervisors: Prof J Stubbs, Dr M Hopkins, Prof G Finlayson, Dr K Beaulieu
 23 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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The role of extracellular vesicles in lung epithelial cell communication in health and disease

University of Salford School of Science, Engineering and Environment
There is an opportunity to apply for a widening participation scholarship (available to UK candidates or those eligible for UK fees) can be found here. Read more
 Supervisor: Dr P Miklavc
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Hydration, metabolic health and physical function across adulthood (Ref: SSEHS/LJBRC)

Loughborough University School of Sport, Exercise and Health Sciences
This project takes an integrative physiology approach to understand how hydration/24-h water intake influence metabolic health and physical function in young/older adults, particularly in the context of climate change/global warming. . Read more
 Supervisors: Dr L James, Dr N Martin, Dr H Dugdale, Dr J Škarabot
 30 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more
 Supervisors: Dr M Hussain, Dr T Nasim, Prof MR Boyett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MScR - Determining the genetic and circadian basis of bipolar disorder using Drosophila

University of Bristol School of Physiology, Pharmacology & Neuroscience
Circadian rhythms and sleep are evolutionarily conserved from fruit flies (Drosophila) and are fundamental as well as vital to biology and health (Jagannath et al., 2017; Menet and Rosbash, 2011). Read more
 Supervisor: Prof J Hodge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Control of bone shape and function by the extracellular matrix Fibrillin-1

University of Liverpool Institute of Life Course and Medical Sciences
Bones are tightly regulated structures that remodel their structure to adapt to changes in their mechanical environment. With ageing, this mechanical response is often dampened, leading to bone loss and weakness. Read more
 Supervisor: Dr B Poulet
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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