Pharmacology PhD Research Projects PhD Projects, Programmes & Scholarships in Dundee

We have 11 Pharmacology PhD Research Projects PhD Projects, Programmes & Scholarships in Dundee

Targeting Ras palmitoylation for the treatment of cancer

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Supervisor: Dr N Fraser

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigation of short-term effects of colchicine on blood proteins using proteomics

University of Dundee School of Medicine

The anti-inflammatory medication colchicine has been shown to significantly improve cardiovascular outcomes post heart attack and in chronic heart disease patient groups, suggesting it may be a suitable candidate for repurposing in cardiovascular diseases. Read more

Supervisors: Prof G Rena, Dr I Mordi, Prof C Lang

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Lessening Health Inequalities in Type 2 Diabetes Through Innovative Drug Repurposing

University of Dundee School of Medicine

Most older type 2 diabetes (T2D) drugs were developed through pre-clinical studies and then trials that model T2D as it is experienced by older white people (1). Read more

Supervisor: Prof G Rena

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Vascularisation of tumour organoids for mechanistic and drug development

University of Dundee School of Medicine

Gliomas such as are the most common form of brain tumour, a subset Glioblastoma (GBM) are devastating adult brain cancer with high rates of recurrence and treatment resistance. Read more

Supervisors: Dr C Murdoch, Dr S Banerjee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating how dormant senescent cells can drive drug-resistance following chemotherapy

University of Dundee School of Medicine

Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Using chemical-genetics to inhibit and characterise “undruggable” enzymes

University of Dundee School of Medicine

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigations into the protective actions of CBD in the early synaptic deficits in dementia.

University of Dundee School of Medicine

Accumulation of hyper-phosphorylated tau is a key event in Alzheimer’s disease (AD). Aberrant changes in tau cause synaptic abnormalities and cognitive deficits in early AD. Read more

Supervisor: Prof J Harvey

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Therapeutic potential of neurosteroids in the treatment of anxiety and social avoidance

University of Dundee School of Medicine

Neurosteroids are naturally occurring steroid compounds produced by the brain in response to stressful events. Read more

Supervisors: Dr S Martin, Prof J Lambert

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Evaluating the therapeutic potential of leptin-based hexamers in neurodegenerative disease

University of Dundee School of Medicine

Translation of basic research into Alzheimer’s disease (AD) therapies is hindered by our inability to turn promising lab results into drugs that can be taken by patients. Read more

Supervisors: Prof J Harvey, Dr C Henstridge, Dr A McNeilly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Molecular characterisation of the factors driving lung fibrosis

University of Dundee School of Life Sciences

Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function. At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more

Supervisors: Prof S Arthur, Dr H McSorley

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Glueing proteins together with small molecules

University of Dundee School of Life Sciences

Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more

Supervisor: Prof A Ciulli

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 11 Pharmacology PhD Research Projects PhD Projects, Programmes & Scholarships in Dundee

Pharmacology PhD Research Projects PhD Projects, Programmes & Scholarships in Dundee

We have 11 Pharmacology PhD Research Projects PhD Projects, Programmes & Scholarships in Dundee

University of Dundee

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