Pharmacology (breast) PhD Projects, Programmes & Scholarships

We have 8 Pharmacology (breast) PhD Projects, Programmes & Scholarships

Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

Queen’s University Belfast School of Pharmacy

One in two people will develop cancer in their lifetime and it is a leading cause of death. While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. . Read more

Supervisor: Dr N Buckley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Regulation of CaaX protein processing

Queen’s University Belfast School of Pharmacy

USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types, as well as the migration of a range of cancer cells (NSCLC, breast, ovarian, osteosarcoma). . Read more

Supervisor: Dr J Burrows

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer Neuroscience: Investigating the impact of non-CNS tumours on neuronal plasticity in the brain

University of Nottingham School of Life Sciences

Cancer is one of the leading causes of death worldwide, resulting in approximately 18 million new cases and 10 million deaths each year. Read more

Supervisor: Dr G Sheridan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the impact of galectin-ligand interaction on cancer cell resistance to chemotherapeutic treatment

University of Liverpool Institute of Life Course and Medical Sciences

Galectins are multifunctional carbohydrate-binding proteins that are expressed by many types of human cells. Changes of galectin expression commonly occur in cancer (e.g. Read more

Supervisor: Prof LG Yu

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Analysing the role of statins in cardiovascular protection

University of Liverpool Department of Pharmacology and Therapeutics

Drug-induced cardiovascular toxicity is a major problem affecting a number of cancer chemotherapy drugs (Cross et al., 2015). Read more

Supervisors: Dr M Cross, Dr B Wilm, Dr AM Mondru

Year round applications PhD Research Project Self-Funded PhD Students Only

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Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

University of Liverpool Department of Pharmacology and Therapeutics

Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Read more

Supervisors: Dr M Cross, Prof C Goldring

Year round applications PhD Research Project Self-Funded PhD Students Only

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Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Supervisor: Dr T You

1 August 2024 PhD Research Project Self-Funded PhD Students Only

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We have 8 Pharmacology (breast) PhD Projects, Programmes & Scholarships

Pharmacology (breast) PhD Projects, Programmes & Scholarships

We have 8 Pharmacology (breast) PhD Projects, Programmes & Scholarships

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