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We have 105 Pharmacology (cell) PhD Projects, Programmes & Scholarships

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Pharmacology (cell) PhD Projects, Programmes & Scholarships

We have 105 Pharmacology (cell) PhD Projects, Programmes & Scholarships

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Molecular mechanism of vimentin induced epithelial mesenchymal transition (EMT) and stemness in cancer cells

Queen Mary University of London Institute of Dentistry
Background. Most cancers are epithelial in origin and arise from a single progenitor cell, similar to an embryo, to become a clone of cells. Read more
 Supervisors: Prof A Waseem, Dr H Tummala, Dr F Flores-Borja
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Possible role of mutant vimentin in cancer progression and metastasis

Queen Mary University of London Institute of Dentistry
Background. This project will investigate the role of the cytoskeletal protein vimentin in cancer progression and metastasis using cell and molecular biology approaches. Read more
 Supervisors: Prof A Waseem, Dr F Flores-Borja, Dr H Tummala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Engineering human tissue in vitro: development, characterisation, and application

Durham University Department of Biosciences
Tissues in the human body have a defined structure in that their growth and differentiation have developed in specific ways to create a cellular architecture… Read more
 Supervisor: Prof S Przyborski
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Biological role of neuropeptides and their receptors

University of Reading School of Pharmacy
Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well. Read more
 Supervisor: Dr L Lander
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer

University of Reading School of Pharmacy
Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more
 Supervisor: Prof D Widera
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Greenwich School of Pharmacy (Medway Campus)
Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more
 Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Kent Medway School of Pharmacy
Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more
 Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating how dormant senescent cells can drive drug-resistance following chemotherapy

University of Dundee School of Medicine
Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more
 Supervisors: Dr A Saurin, Dr T Ly
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Targeting Ras palmitoylation for the treatment of cancer

University of Dundee School of Medicine
Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more
 Supervisor: Dr N Fraser
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more
 Supervisors: Dr S Shnyder, Dr S Kantamneni
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the impact of galectin-ligand interaction on cancer cell resistance to chemotherapeutic treatment

University of Liverpool Institute of Life Course and Medical Sciences
Galectins are multifunctional carbohydrate-binding proteins that are expressed by many types of human cells. Changes of galectin expression commonly occur in cancer (e.g. Read more
 Supervisor: Prof LG Yu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of extracellular vesicles in signalling between cardiovascular cell types in metabolic diseases and in cardioprotective therapies

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy
We are to understand how EVs induce and affect cardiovascular diseases. To this end, we investigate its changes in disease models of the cardiovascular system and in its comorbidities, e.g., metabolic diseases. Read more
 Supervisor: Dr Z Giricz
 Year round applications  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Effects of FADS2 single-nucleotide polymorphisms on clathrin-mediated endocytosis in human induced pluripotent stem cell-derived neurons

Cardiff University Cardiff School of Medicine
Hodge Centre for Translational Neuroscience. “Towards innovative treatments for mental illness”. Cardiff University Neuroscience and Mental Health Innovation Institute. Read more
 Supervisor: Prof A Harwood
 7 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Investigating the roles that G protein coupled receptors play in hypertension

University of Leicester Molecular and Cell Biology
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
 Supervisor: Dr J Willets
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

The University of Manchester Faculty of Biology, Medicine and Health
Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more
 Supervisors: Prof D Brough, Dr K Couper
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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