Pharmacology (colorectal cancer) PhD Projects, Programmes & Scholarships

We have 5 Pharmacology (colorectal cancer) PhD Projects, Programmes & Scholarships

Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more

Supervisors: Dr S Shnyder, Dr S Kantamneni

Year round applications PhD Research Project Self-Funded PhD Students Only

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Hepatic Models to personalise cancer chemotherapy

University of Liverpool Department of Pharmacology and Therapeutics

The most commonly used chemotherapy regimens for colorectal cancer with liver metastases are oxaliplatin combined with 5-FU and leucovorin, i.e. Read more

Supervisors: Prof C Goldring, Dr A Chadwick, Prof IC Copple, Dr S Pushpakom

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more

Supervisors: Dr S Shnyder, Prof S El-Khamisy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Supervisor: Dr T You

1 August 2024 PhD Research Project Self-Funded PhD Students Only

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Regulation of CaaX protein processing

Queen’s University Belfast School of Pharmacy

USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types, as well as the migration of a range of cancer cells (NSCLC, breast, ovarian, osteosarcoma). . Read more

Supervisor: Dr J Burrows

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 5 Pharmacology (colorectal cancer) PhD Projects, Programmes & Scholarships

Pharmacology (colorectal cancer) PhD Projects, Programmes & Scholarships

We have 5 Pharmacology (colorectal cancer) PhD Projects, Programmes & Scholarships

Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

Hepatic Models to personalise cancer chemotherapy

Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives

Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

Regulation of CaaX protein processing

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