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We have 12 Pharmacology (control system) PhD Projects, Programmes & Scholarships

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Pharmacology (control system) PhD Projects, Programmes & Scholarships

We have 12 Pharmacology (control system) PhD Projects, Programmes & Scholarships

Using chemical-genetics to inhibit and characterise “undruggable” enzymes

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Lessening Health Inequalities in Type 2 Diabetes Through Innovative Drug Repurposing

Most older type 2 diabetes (T2D) drugs were developed through pre-clinical studies and then trials that model T2D as it is experienced by older white people (1). Read more

Targeting Ras palmitoylation for the treatment of cancer

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Microneedle delivery systems for minimally-invasive patient diagnosis/monitoring

In this project, a novel type of integrated system will be investigated that will by-pass the skin barrier. On its surface will be multiple microscopic needles that pierce the skin without causing any pain – the sensation is said to feel like a cat’s tongue or sharkskin. Read more
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