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We have 20 Pharmacology (immune) PhD Projects, Programmes & Scholarships

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Pharmacology (immune) PhD Projects, Programmes & Scholarships

We have 20 Pharmacology (immune) PhD Projects, Programmes & Scholarships

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(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

The University of Manchester Faculty of Biology, Medicine and Health
Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more
 Supervisors: Prof D Brough, Dr K Couper
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Investigating the neuro-stromal-immune interactions in inflammageing and osteoarthritis.

University of Greenwich School of Pharmacy (Medway Campus)
Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) including osteoarthritis. Age-associated chronic low-grade inflammation (inflammageing) is a hallmark of osteoarthritis. Read more
 Supervisor: Dr S Ashraf
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Interaction between innate immune activation and endothelial cells, linked to adverse cardiovascular events

University of Liverpool Institute of Systems, Molecular and Integrative Biology
The complement system is a key component of the immune response. Maintaining a balance between activation and inhibition of the complement system is key to preserving tissue homeostasis and enabling immune surveillance. Read more
 Supervisors: Dr N Liptrott, Dr R Rainbow, Prof C Dart
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Determining the biocompatibility of, novel, nano-silica coated surfaces on oral and gastrointestinal immune barriers

University of Liverpool Department of Pharmacology and Therapeutics
The interaction of nanoparticles with cells, particularly those that are immune-competent, may affect their biocompatibility, particularly when applied in long-term situations. Read more
 Supervisors: Dr N Liptrott, Prof R Williams
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genetic Engineering of Immune Effector Cells for CAR therapies using a Peptide Technology

Queen’s University Belfast School of Pharmacy
Chimeric antigen receptor (CAR)-T therapies have demonstrated remarkable treatment outcomes and several CAR-T therapies now approved for treatment of haematological malignancies. Read more
 Supervisors: Dr E McErlean, Prof H McCarthy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Virus antigenic evolution under immune pressure

Agency for Science, Technology and Research (A*STAR) A*STAR Infectious Diseases Labs
About the Project. The persistent evasion of COVID-19 from vaccines and monoclonal antibody therapeutics underscores the critical need to comprehend how endemic and zoonotic viruses evolve to counter antibody-mediated immune responses. Read more
 Supervisor: Dr M Tay
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer

University of Reading School of Pharmacy
Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more
 Supervisor: Prof D Widera
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

University of Nottingham School of Medicine
Implanted medical devices are crucial in healthcare, valued at around £400 billion globally, however there is a high failure rate, often due to the foreign body reaction, where a fibrotic capsule forms around the implant with associated inflammation, loosening and infection. Read more
 Supervisors: Prof M Alexander, Prof AG Ghaemmaghami, Dr D H Kim, Prof BO Ollivere
 30 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

The University of Manchester Faculty of Biology, Medicine and Health
A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more
 Supervisors: Dr R Hager, Dr M Harte, Dr J Glazier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Greenwich School of Pharmacy (Medway Campus)
Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more
 Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Kent Medway School of Pharmacy
Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more
 Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Finding new targets for treating gut inflammation

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy
The gastrointestinal (GI) mucosa is constantly exposed to a wide variety of luminal aggressors, including gastric acid, pepsin, bile acids and bacterial components. Read more
 Supervisor: Dr Z Zádori
 Year round applications  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Pharmacological effects of cannabidiol (CBD) on mesenchymal stem cells in endometriosis

University of Reading School of Pharmacy
Endometriosis is a common long-term health condition that affects around 190 million women of reproductive age worldwide. It causes severe pain during periods, sex, going to the toilet, and sometimes just general pelvic discomfort, bloating, and tiredness. Read more
 Supervisors: Prof D Widera, Dr G Cottrell
 31 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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PhD position in antiviral immunity and vaccinology (m/f/d)

University Hospital of Munich Clinical Pharmacology
The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. Read more
 Supervisor: Prof S Rothenfusser
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

Queen’s University Belfast School of Pharmacy
One in two people will develop cancer in their lifetime and it is a leading cause of death.  While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. . Read more
 Supervisor: Dr N Buckley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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